Objectives: To investigate of Lonal praparation for antidiabetic effects in diabetic rats induced by alloxan. Methods: Diabetic animals were randomly divided into 3 groups and treated orally with different doses (100 mg/kg body weight) Lonal extract once a day for 21 days. The body weight of each animal was determined, to assess any possible weight gain or loss in experimental animals compared with control groups. On the 21st day, those administered 100 mg/kg of Lonal showed more promising results with regard to fasting blood glucose (FBG), water intake when compared to those treated with other doses. Therefore, 100 mg/kg dose was used for further biochemical studies. Total cholesterol (TC), triglycerides (TG), Alat, Asat, ALP, low density lipoproteins (LDL) and high density lipoproteins (HDL) levels, on normal and diabetic rats treated with the dose of 100 mg/kg, were evaluated. Results: The flower extract shows a significant (p