1.Development of Application of Acupuncture and Moxibustion in the Sultanate of Oman
Chinese Journal of Information on Traditional Chinese Medicine 2015;(3):13-15
Acupuncture and moxibustion is classified as category of alternative medicine and has been incorporated into the public medical institution in Oman. There are two public hospitals which have set up acupuncture and moxibustion service at present, but only in outpatient department regions. Private clinics of traditional Chinese medicine are not uncommon, and the local government is constantly improving the management policy on it now. The musculoskeletal system diseases are predominant diseases treated by acupuncture and moxibustion, and obesity female is mostly common. Compared with other Arabian countries, Oman is more inclusive to foreign culture and the local government attaches great importance to acupuncture and moxibustion, so there is much better development space for acupuncture and moxibustion in Oman.
2.Investigation on the distribution of the components of metabolic syndrome in 500 cases of stroke
Jianguo ZHAO ; Xiangyu ZANG ; Bozhen NIU ; Boying TONG ; Xiaoyan DONG ; Shanshan WANG
Clinical Medicine of China 2011;27(1):32-34
Objective To explore the relation of stroke and metabolic syndrome (MS), and provide theoretical evidence for prevention of stroke and MS. Methods Five hundred stroke patients accompanied with MS were enrolled, and divided into different types according to the distribution of the components of metabolic syndrome and abnormal metabolic condition. The systolic blood pressure(SBP) ,diastolic blood pressure( DBP),fasting glycemia ( FPG ), triglycerides ( TG ), total cholesterol ( TC ), low density density lipoprotern-cholesterol (LDL-C), high density density lipoprotern-cholesterol (HDL-C)of each patient were detected and recorded. Results Among these stroke patients with MS, most patients were 60 - 69 years old ( 39.60% ), and there was no significant difference between two gender( P = 0. 545 ). Among each component of MS, hypertension was most related to MS;patients complicated with hypertension + hyperlipidemia + hyperglycemia were the most major proportion of stroke patients with MS(48. 00% ). Conclusion MS and its components are all risk factors for stroke,and the more complication the patients had,the more patients suffered from stroke with MS. Targeted interventions of different type of abnormal condition has important prevention effect on MS and stroke.
3.Recent advance in mechanism of cognitive impairment patients with comorbid metabolic syndrome through PI3K/Akt signaling pathway
Bozhen NIU ; Xiangyu ZHANG ; Yang XU ; Kai TIAN ; Chunyan FENG
Chinese Journal of Neuromedicine 2022;21(1):92-95
Multiple studies has indicated an increased risk of cognitive decline in patients with metabolic syndrome (MetS), and treatments targeting the abnormal metabolic components of MetS are considered to be able to prevent and delay the onset of dementia. Phosphatidylinosito-3 kinase/protein kinase B (PI3K/Akt) signaling pathway plays an important role in peripheral metabolism and brain biological function, and is a common signaling pathway in the pathogenesis of MetS and cognitive impairment. PI3K/Akt signaling pathway has been attempted to use as an entry point for treatment of cognitive impairment related with MetS. In our research, the mechanism of cognitive impairment in MetS through PI3K/Akt signaling pathway is reviewed from aspects of glucose uptake, cholesterol synthesis, acetylcholine level, Aβ aggregation and tau protein phosphorylation in brain, which aims to clarify how PI3K/Akt signaling pathway participates in cognitive impairment related to comorbid MetS, and to find new targets for treating cognitive impairment related to comorbid MetS.