OBJECTIVE To investigate the distribution characteristic and drug resistance status in pathogens isolated from infected urinary tract and offer the scientific evidence for reasonable usage of antibiotics.METHODS Totally 257 strains of pathogens isolated from infected urinary tract were identified by auto-microbiological assay and antibiotic susceptibility test was performed by K-B method.RESULTS Among 257 strains,Escherichia coli accounted for 60.3%,ranking the first.Enterococci ranked the second,accounting for 10.5%.Except for 100% sensitivity to imipenem,meropenem,vancomycin and teicoplanin,the pathogens were resistant to the other antibiotics in different degrees.The detection rate of extended-spectrum beta-lactamases(ESBLs) producers in E.coli and Klebsiella pneumoniae were 40.0% and 37.5%,respectively.CONCLUSIONS The drug resistance of pathogens from infected urinary tract is on the rise.We should strengthen monitoring and controlling of it.

OBJECTIVE To investigate drug-resistance status and changing tendency of Escherichia coli inducing hospital infection to provide the evidence for reasonable use of antibiotics. METHODS Pathogenic bacteria were isolated and identified according to the National Clinical Laboratory Manipulation Rules. Drug resistance profile was analyzed by K-B methods. RESULTS In the four years, the resistance to seventeen common antibiotics in E. coli was on the rise. The resistance rate to ampicillin was the most highest, 90.8-94.2%. There was no strain that was resistant to imipenem and meropenem. Detection rate of extended spectrum ?-lactamases (ESBLs) producing E. coli increased from 13.2% to 32.0%. CONCLUSIONS Drug-resistance status of E. coli inducing hospital infection is very serious. We should strengthen the management of antibiotic use and control the spread and prevalence of the drug-resistant bacteria.

ObjectiveTo observe the curative effect of intensive regulating lipid by atorvastatin in the treatment of unstable angina and its influence on serum high sensitive C-reactive protein(hs-CRP).Methods60 patients with unstable angina were randomly divided into two groups:the routine treatment group( basic treatment plus atorvastatin 10mg/d),the atorvastatin intensive treatment group( basic treatment plus atorvastatin 40mg/d.)The courses of treatment were both 8 weeks.The differences in the amount of serum hs-CRP,blood fat,the effect of electrocardiogram and the use of glyceryl trinitrate before and after the treatment were observed and compared.Results The differences in the angina curative effect and the amount of serum hs-CRP between the two groups were statistically sig nificant( all P ＜0.05 ).ConclusionShort-term intensive regulating lipid by statins was effective in treating unstable angina,and could quickly relieve the phlogosis in the vessels,prevent the unstable plaque from breaking and the thrombopoiesis,and thus prevent the occurrence of cardiovascular disease.

Objective To investigate the characteristics of clinical course in elderly patients and young-mid-dle-aged patients with upper gastrointestinal hemorrhage. Methods 417 hospitalized patients were divided into eld-edy group (≥60 yrs,198 cases) and young-middle-aged( <60 yrs,219 cases). All patients were diagnosed upper gastrointestinal hemorrhage by endoscopy. Results Endoscopy diagnosis included the first common cause to upper gastrointestinal hemorrhage was peptic ulcer, whereas more gastric ulcer were seen in elderly patients and more duo-denal ulcer were seen in young-middle-aged patients(23.7% vs 12.8%, 39.7% vs 21.7%, P <0.01). More eld-erly patients had a history of using Aspirin or NSMDs (17.1% vs 5.0%, P <0.01). The number of circulatory fail-ure and blood transfusion necessary were significantly increased, the mean duration of hospital stay was longer in eld-erly group than in young-middle-aged group(P<0.05). Conclusion The elderly patients have a more complicated clinical course than those young-mlddle-aged patients. Endoscopy is a necessary and effective method for both diagno-sis and treatment.

Adult ; Aged ; Child ; Child, Preschool ; Female ; Gastric Lavage ; Humans ; Male ; Middle Aged ; Mushroom Poisoning ; therapy

OBJECTIVE To investigate the clinical characteristics and the present condition of infective diabetic foot. METHODS A total of 100 cases with infective diabetic foot were classified into the wet gangrene and composite gangrene, and treated by the systemic and local modality in combination. RESULTS The cure rate of the wet gangrene and composite gangrene was 29.5% and 18.2%, respectively and the effective rate was 83.3% and 68.2%, respectively. CONCLUSIONS The combined therapy is effective for the treatment of diabetic foot.

This paper introduces the design and implementation of Bluetooth wireless management and monitoring system. Combined with hospital information system, this system replaces the current monitoring system in hospital, and thus the efficiency of hospital can be improved.

Objective To evaluate the clinical application value of percutaneous lung biopsy by CT fluoroscopy.Methods we analysed 31 cases of percutaneous lung biopsy by CT fluoroscopy which were proved by operation or pathology,with the puncture needle produced by Cook Co..The main point are: choose the best layer,point,angle,depth,draw and obtaining at many points.Results In these 31 cases,accurate diagnosis is 29 cases,include 9 cases of adenocarcinoma,6 cases of SqCa,2 cases of small cell carcinoma,1 case of metastatic carcinoma,1 case of alveolar cell carcinoma,5 cases of TB,4 cases of infection,1 case of inflammatory pseudotumor.The diagnosis accurate rate is 93.5%.2 cases were not diagnosed accurately,2cases of pneumothoras,complication rate is 6.5%.Conclusion The percutaneous lung biopsy by CT fluoroscopy was high diagnosis accurate rate,less of complication,this is a safe,effective,simple and practical way for diagnosing lung diseases.

Objective To study the impact of rehabilitation training combined with low molecular heparin calcium on functional recovery and venous thrombosis of postoperative period of hip fracture in the elderly.Methods 86 elderly patients with hip fracture surgery were divided into the control group(43 cases)and observation group (43 cases)according to random number table method.The control group was given low molecular heparin calcium, and the observation group was given rehabilitation training combined with low molecular heparin calcium.After four weeks,the hip functional recovery and venous thrombosis occurrence were observed in the two groups.The levels of blood rheology indicators such as blood high shear viscosity,shear viscosity,low shear viscosity,erythrocyte aggrega-tion index and coagulant function index of thrombin time and D -dimer were detected.Results The scores of hip joint pain,joint function,joint mobility,deformity and Harris score in the observation group were higher than those in the control group,the differences were statistically significant(t =3.713,3.224,3.345,1.861 and 8.087,all P <0.05).The incidence rate of venous thrombosis in the observation group was 6.89%,which was lower than 23.26%in the control group,the difference was statistically significant (χ2 =4.440,P =0.035).After 4 weeks treatment,the levels of the whole blood high shear viscosity,shear viscosity,low shear viscosity and erythrocyte aggregation index in the observation group were lower than those in the control group,the differences were statistically significant (t =2.092,2.590,1.716 and 2.590,all P <0.05).After treatment,the level of D -dimer in the observation group was lower than that in the control group,and the prothrombin time in the observation group was higher than that in the con-trol group,the differences were statistical significance(t =7.510 and 2.151,all P <0.05).Conclusion The rehabil-itation training combined with low molecular heparin calcium can promote hip joint function recovery of postoperative period of hip fracture in the elderly,reduce the incidence of venous thrombosis,improve blood rheology and blood coagulation function indicators.

Objective To study the adverse effect of omethoate on DNA in mice testicle cells in vivo.Methods 24 mice were randomly divided to 4 groups:control(no omethoate),1,2 and 4 mg/kg.omethoate was given by gavage one time a day for consecutive 7 days.DNA damage was detected by single cell gel electrophoresiss (SCGE).Results At the concentration of 1,2,4 mg/kg,omethoate induced DNA damage in mice testicle cells in vivo with an obvious dose-effect relationship(r=0.969 5).Conclusion Omethoate may cause DNA damage in mice testicle cells.