Objective To determine the association between homocysteine and severity of large cerebral artery atherosclerosis.Methods Total 152 ischemic stroke patients were evaluated using transcranial Doppler(TCD),magnetic resonance angiography(MRA) or digital substraction angiography(DSA).Severity of cerebral artery atherosclerosis was scaled by number of stenosed or occluded artery.Results There were 83 patients in low level homocysteine group with mean Hcy level(15.31?3.08)?mol/L,while 69 patients in high level homocysteine group with mean Hcy(34.47?21.38)?mol/L.Number of abnormal intra-and extra-artery was 1.86?1.51 and 1.52?1.46 respectively.No significant difference was demonstrated in the number of abnormal artery between two groups.No correlation was noted between Hcy and number of abnormal artery.Conclusion There is no relationship between high homocysteine and severity of large cerebral artery atherosclerosis in ischemic stroke patients.Homocysteine might be the marker of the disease.

Objective To investigate the MRI features of peliosis hepatis (PH).Methods Nine patients with pathologically proven PH were retrospectively included.Plain scan and contrast-enhanced MRI of the abdomen were performed on all patients before operation.All clinical,pathological and MR imaging data of patients were collected.The MR image analysis of the lesion included the number,location,size,shape,lesion margins,signal intensity,and enhancement pattern.Results Eleven lesions were detected in 9 patients,with 10 lesions in the right lobe of the liver and 1 lesion in the left lobe.The maximum diameter of the 11 lesions was 0.7 cm to 8.8 cm (mean 3.7 cm).All 11 lesions were round or oval in the shape.Seven lesions had clear boundaries and 4 lesions had blurred boundaries.Signal intensity of 2 lesions were homogeneous,while 9 lesions had heterogenous signal intensity on plain san.Ten lesions showed slightly hypointense on T1WI,slightly hyperintense on T2WI and mildly progressive enhancement.These lesions were weakly enhanced and showed slight cluster-like mild enhancement in the arterial phase.The enhancement scope of the lesions gradually filled into the interior in the portal vein phase and the signal intensity was slightly higher than liver in delay phase.One lesion showed hypointense on T1WI and hyperintensity on T2WI.After the enhancement,the lesion was evenly enhanced and showed continuous enhancement.On DWI,11 lesions were slightly hyperintense.The signal intensity of 9 lesions were equal to that of the liver,and the signal intensity of the 2 lesions was slightly higher than that of the liver on the ADC map.Conclusion MRI signs of PH have certain characteristics,which can help diagnosis and differential diagnosis.