1.Studies on Narrowleaf Sibiraea(Sibiraea angustata) in Regulating Lipoid Metabolism
Xiaoli WANG ; Jiming GUO ; Bingxun YANG
Chinese Traditional and Herbal Drugs 1994;0(09):-
Liu Tea (Sibiraea angustata) at doses of 8.5 and 15.0g/kg ig coild redice TG, ?-LP, TC and elevate HDL-C levels of normal of normal or hyperlipoidemia rat. In vitro experiments indcated that S.angustata may promote the eatabolism of FFA. The contents of FFA in rat serum showed significant elevation in S. angustata treated groups as compared with the control. In addition, fat cells were smaller in S. angustat treated rats and mucoid changes could be seen under microscope. These results suggested that S. angustat could iegulate the metabolism of lipoid.
2.Impact of miR-873 on human prostate cancer PC3 cells invasion
Tan LI ; Chenguang LI ; Yan LIU ; Bingxun LI ; Xianxu YANG
Military Medical Sciences 2015;(8):610-613
Objective To identify the role of miR-873, which may regulate the expression of survivin,in human pros-tate cancer PC3 cells invasion.Methods PC3 cells were cultured in vitro, and changes of cellular morphology were ob-served by phase contrast microscope.miR-873,which might regulate the expression of survivin,was predicted by bioinforma-tics and identified using dual luciferase report system.Expressions of miR-873 and survivin were determined using real-time quantitative PCR( qRT-PCR) and Western blotting after transfection of miR-873 mimics.The invasion of PC3 cells was de-tected in vitro by Transwell chamber.Results The expression of survivin was positive by immunofluorescence cytochemis-try.Using dual luciferase reporter system, miR-873 could inhibit the expression of survivin by binding to its mRNA 3′UTR.Results of qRT-PCR and Western blotting showed that overexpression of miR-873 down-regulated the expression of survivin.The invasion of PC3 cells was suppressed by over-expression of miR-873.Conclusion MiR-873 may negatively regulate the expression of survivin in human prostate cancer PC3 cells and inhibit cell invasion.
3.Surveillance & management of out-of-plan re-operations
Wanning LIANG ; Dan WANG ; Mo XING ; Ping BAO ; Bingxun HOU ; Jing LIU ; Fengling WANG ; Xu YANG
Chinese Journal of Hospital Administration 2010;26(2):115-117
A series of surveillance and management actions was taken to minimize out-of-plan re-operations. These actions include: 1) Building and completing the surveillance and management mechanism against unplanned re-operations; 2) Building a real-time surveillance and reporting mechanism; 3) Enhancing quality control and continuous improvement at the operating departments; 4) Enhancing the supervision on regulations implementation by quality control departments of the hospital; 5) Enhancing quality control for medical records; 6) Building a feedback mechanism for surveillance results; 7) Building a penalty and reward mechanism. Efforts for one year and a half on such surveillance and management proved successful, as the incidence of out-of-plan re-operations fell from 1.7% before these actions to 1.0% afterwards.