Objective: To observe the anemia situation and pregnancy outcome of pregnant women with iron deficiency anemia ( IDA) treated with polysaccharide iron complex. Methods:Totally 102 patients with IDA were randomly divided into the control group (51 cases) and the study group (51 cases). The control group was treated with iron dextran tablets orally, and the study group re-ceived polysaccharide iron complex. The improvement of anemia and the pregnancy outcome were compared, and the adverse reactions were recorded. Results:After the treatment, hemoglobin ( Hb) , serum iron ( SI) , serum ferritin ( SF) and serum transferrin receptor ( sTfR) at 24-week pregnancy and before the delivery, the red cell count ( RBC) and mean corpuscular hemoglobin ( MCH) before the delivery in the study group were all better than those in the control group (P<0. 05). The incidence of adverse reactions in the two groups was similar. Conclusion:Polysaccharide iron complex can improve anemia status of pregnant women with IDA, which is worthy of widely clinical use.