ObjectiveTo study the effect of three-level monitoring mode in reducing complications of pediatric PICC catheter tube and improving the quality of care for children. Methods64 cases of children with PICC catheter in our hospital from September 2009 to August 2011 receiving three-level monitoring modes were set as the experimental group.67 patients with conventional care from September 2007 to August 2009 were set as the control group.The incidence of catheter complications in children,success rate of catheter puncture and tube indwelling time for the two groups were observed. Results The complications occurred in 9 cases,accounting for 14.06％ in the experimental group.The complications occurred in 25 cases in the control group,accounting for 37.31％.The puncture success rate was 89.06％ in the experimental group,and the control group was 79.10％.The average time of tube indwelling in the experimental group was higher than the control group.The difference was significant. ConclusionsThe effect of three-level monitoring modes to reduce pediatric PICC catheter complications and improve quality of care in children with catheter is significant,it can increase the success rate of puncture and prolong tube in-dwelling time.

Objective To explore the anti- inflammatory of pricking blood therapy in acute gouty arthritis rats. Methods 60 Sprague-Dawley rats were equally divided into normal group, bloodletting normal group, sham group, arthritis group, bloodletting group and ibuprofen group. The acute gouty arthritis model was established with injecting uric acid sodium salt into the right ankle joint cavity. The ibuprofen group was administrated with ibuprofen intragastrically, the bloodletting normal group and bloodletting group were pricked the right Kunlun (BL60) acupoint. The cross section diameter of the right ankle joint were measured before and after treatment. Levels of mRNA and protein of interleukin (IL)-10 and IL-4 expressed in ankle were determined with RT-PCR and Western blotting Results The cross section diameter increased in the bloodletting group compared with the normal group after treatment (P<0.05), and decreased (P<0.05) compared with the arthritis group and the ibuprofen group, while the expression of IL-10 mRNA increased (P<0.05) compared with the normal group, the arthritis group and the ibuprofen group, as well as the IL-10 protein compared with the normal group and the arthritis group (P< 0.05). The expression of IL-4 mRNA and protein increased without significance (P>0.05) in the bloodletting group compared with the normal group. Conclusion IL-10 may play a role of anti-inflammatory in pricking bloodletting therapy for acute gouty arthritis.