Objective To observe continuous venous-venous hemofiltration (CVVH) for treatments and cares of severe acute pancreatitis(SAP). Methods From August 2004 to August 2006, 15 cases with SAP were in conventional treatment (the control group), from September 2006 to August 2010, 20 cases with SAP were nursed with CVVH(the observation group). We surveyed patients' vital signs (including body temperature, heart rate, breathing and blood pressure),mental symptoms, abdominal signs and monitored liver and kidney functions. Additionally we executed APACHE Ⅱ scores. We analyzed them retrospectively. Results The afore - mentioned indexes of two groups were significant in statistics, the observation group had lower incidence of MODS、MOF than the control group after 10 days caring. Conclusions The CVVH could correct systemic inflammatory reaction of SAP and prevent complications. Standard technical operation and intensive nursing can ensure smooth process of CVVH and decrease complications caused by CVVH.

Objective To know the effects of partial closure combined with MgSO_4 hydropathic com-press for injury because of highly irritating drugs extravasation. Methods Divided 144 patients with injury because of highly irritating drugs extravasation into the treatment group and the control group randomly, there were 72 cases in each group. 50% MgSO_4 was used in the control gnmp, partial closure was used in the treat-ment group in addition. Compared the medical effects between the two groups. Results Compared with the control group, the medical effects of injury because of highly irritating drugs extravasation in the treat-ment group was better. Conclusions Partial closure combined with MgSO_4 hydropathic compress is a kind of effective method for patients with injury because of highly irritating drugs extravasation, which can quickly promote absort by surrounding tissue and release pains.