Objective To study the therapeutic effect and complication of external beam radiotherapy (EBR) plus intracavitary brachytherapy (IB) on nasopharyngeal carcinoma(NPC). Methods 52 patients with stage T 1,T 2 NPC were divided into two groups, 26 patients treated by EBR and the other 26 patients treated by EBR plus IB (combined radiotherapy group). IB was given to the patients of combined radiotherapy group when the external radiotherapy dose amounted to 40Gy,50Gy and 60Gy, respectively. Results The 3-year local control rates of combined radiotherapy group and EBR group were 100% and 73.08%, respectively (P0.05). Conclusions External beam radiotherapy combined with intacavitary brachytherapy for stage T 1, T 2 NPC may rise the local control rates, and reduce the exteral beam radiation dose and the complication.