Objective To explore the psychological behavior features between different sexual children with oppositional defiant disorder(ODD).Methods The subjects were sampled from grade 1 to 5 in a primary school in Ji-nan,Shandong Province.According to the diagnosed criteria,42 pupils were diagnosed ODD,which was the study group,and 556 pupils without ODD became the control group.The pupils and their families were investigated and as-sessed by using Achenbach Child Behavior Checklist (CBCL).Results According to CBCL,there was extremely sig-nificantly higher score of depression,obsessive -compulsive,hyperactive,aggressive,interpersonal behaviors in ODD boys [(5.00 ±3.73)scores,(4.88 ±3.65)scores,(5.21 ±3.49)scores,(1 0.1 0 ±6.85)scores,(2.88 ±1 .99) scores]than those in healthy control group [(1 .65 ±2.61 )scores,(1 .91 ±2.65)scores,(2.46 ±2.63)scores, (3.95 ±4.52)scores,(1 .34 ±1 .61 )scores](t =4.31 ,3.90,4.76,4.33,4.40;P =0.000,0.000,0.001 ,0.000, 0.000).There was significantly higher score of symptoms of somatization,indiscipline,schizoid -like behaviors in ODD boys with [(2.38 ±2.50)scores,(2.63 ±2.70)scores,(3.1 7 ±2.35)scores]than those in healthy control group [(0.85 ±1 .63)scores,(0.1 3 ±1 .76)scores,(1 .51 ±1 .72)scores](t =2.94,2.85,3.37;P =0.007,0.009, 0.002).There was extremely significantly higher score of depression,communication disorder behaviors in ODD girls [(5.44 ±4.1 2)scores,(3.1 1 ±2.93)scores]than those in healthy control group with [(2.50 ±3.34)scores, (1 .36 ±2.08)scores](t =3.57,3.38;P =0.000,0.001 ).A significantly higher score of hyperactive,aggression, cruelty behaviors in ODD girls [(4.67 ±4.41 )scores,(9.33 ±7.82)scores,(1 .1 7 ±1 .79)scores]than those in healthy control group [(1 .87 ±2.38)scores,(3.1 9 ±4.08)scores,(0.24 ±0.66)scores](t =2.67,3.30,2.1 8;P =0.01 6,0.004,0.043).Conclusions According to CBCL,there were more psychological behavior problems in ODD children than healthy children.A significantly higher difference was found in different gender.

Objective: To clinically evaluate the efficacy of electrolyzed oxidizing water (EOW) as a root canal irrigation solution on disinfecting bacteria and removing the smear-layer to keep the non-bacterium state in the root canal. Methods: In the first experiment, 108 single-rooted teeth that needed root canal treatment were randomly divided into two groups. EOW was used as the root canal irrigation solution in the experimental group while 30 ml/L H2O2, saline solution, and 75 g/L EDTA solution were used as controls. Bacteriological examinations were conducted from each tooth before and after treatment with the root canal irrigation solutions. In the second experiment, the 20 fresh human extracted teeth were divided into two groups and treated as same as the first experiment in root canal preparation and irrigation. After irrigation, the apical canal wall was observed using SEM. Results: There was no significant difference in bacterial growth and removing the smear layer between the group using EOW and that using saline solution, 30 ml/L H2O2 and 75 g/L EDTA solution. Conclusion:The results indicate EOW is useful as a clinical root canal irrigation solution.

Objective To observe the influence of Cichorii extract on uric acid and lipid metabolic disorder and discuss the mechanism. Methods Quails were divided randomly into 5 groups by weight:normal group,model group,positive control group and Cichorii extract high and low dosage group,15 quails in each group. The normal group was fed with the common feeder,and the other groups were fed with the yeast powder. Positive control group was given Benzbromarone 20 mg/(kg?d). Cichorii extract high and low dosage group were given Cichorii extract 15,10 g/(kg?d) respectively. Normal and model group were given distilled water. UA,TG,FFA,TC,HDL,LDL level and XOD,ADA,GD activity related to uric acid metabolism were determined after 7 days. Results Compared with normal group,UA,TG,FFA of model group was significantly higher and HDL was significantly lower. Compared with model,Cichorii extract decreased UA,TG,FFA significantly. GD activity in model group increased significantly. Cichorii extract decreased GD activity. There was no significant variance of XOD and ADA activity in each group. Conclusion Cichorii extract had obvious effect in adjusting uric acid and lipid metabolic disorder. The possible mechanism was by decreasing GD activity and decreasing UA,FFA level.

50% cases of risk class Ⅱhad the history of hospitalization due to pneumonia. Conclusions The important risk factors of CAP are the history of hospitalization due to pneumonia, except the aged and concomitant disease. In more than half of CAP cases of the pathogens can not be separated. It is importants to facilitate and promote the experience initial therapy in CAP management.

Objective:To explore the relationship among biochemical indexes and ECG features in patients with unsta‐ble angina pectoris (UAP) .Methods:A total of 130 UAP patients treated in our hospital from Jan 2014 to Jun 2014 were selected .According to presence of inverted T wave or not ,patients were divided into normal T wave group (n =53) and inverted T wave group (n=77);according to presence of elevated ST segment or not ,patients were di‐vided into normal ST segment group (n=66) and ST elevation group (n=64) .Levels of C reactive protein (CRP) , white blood cell count (WBC) ,cardiac troponin T (cTnT) ,creatine kinase isoenzyme MB (CK-MB) ,low density lipoprotein cholesterol (LDL‐C) ,blood uric acid (UA) and TIMI score were compared among all groups .Results:Compared with normal T wave group ,there were significant rise in levels of CRP [ (5.34 ± 1.02) mg/L vs .(9.79 ± 3.18) mg/L] ,WBC [ (8.42 ± 3.19) 109/L vs .(10.34 ± 2.46) 109/L] ,cTnT [ (0.11 ± 0.02)μg/L vs .(0.21 ± 0.04)μg/L] ,blood UA [ (3.98 ± 0.57)μmol/L vs .(4.72 ± 0.86)μmol/L] ,LDL‐C [ (321.52 ± 12.79) mmol/L vs .(357.83 ± 12.14) mmol/L] and TIMI score [ (2.66 ± 1.62) scores vs .(4.58 ± 2.31) scores] in inverted T wave group , P<0.01 all;compared with normal ST segment group ,there were significant rise in levels of CRP [ (6.38 ± 1.77) mg/L vs .(9.75 ± 2.56) mg/L] ,WBC [ (7.59 ± 2.08) 109/L vs .(9.43 ± 2.74) 109/L] ,cTnT [ (0.14 ± 0.03)μg/L vs .(0.23 ± 0.05) μg/L] ,blood UA [ (3.54 ± 0.52) μmol/L vs .(4.71 ± 0.76) μmol/L] ,LDL‐C [ (341.05 ± 12.01) mmol/L vs .(369.23 ± 11.57) mmol/L] and TIMI score [(2.78 ± 1.58) scores vs .(3.92 ± 2.14) scores] in ST elevation group , P<0.01 all .Conclusion:Inverted T wave and ST elevation on ECG are related to status of UAP .Evaluation of patient′s ECG can provide evidence for treatment .

Objective To evaluate the analgesic effect of oxycodone hydrochloride and morphine in preemptive analgesia for abdominal surgery.Methods The 200 patients who received abdominal operation were randomly divided into the oxycodone hydrochloride group (group O) and the morphine group(group M) with 100 patients in each group,and patients of the two groups were given oxycodone hydrochloride and morphine in preemptive analgesia respectively .The VAS, OAA/S and BCS 48 hours after surgery , the frequency of the use of PCIA in 24 hours,the satisfaction of patients ,and the occurrence rate of complications were compared between the two groups .Results There was no significant difference between the two groups in VAS ,BCS,OAA/S,frequency of the use of PCIA and patients satisfaction (P>0.05).The occurrence rate of nausea,vomit,and itch in group O were much lower than that in group M (P<0.05).The occurrence rate of drowsiness in group O was higher than that of group M(P<0.05).Conclusion Compared with morphine,oxycodone hydrochloride has the same analgesia efficiency and less side effect occurrence rate for patients with abdominal operation .

Objective To study the antagonsim of Chinese medicine herbals on the chromsome breakage induced by Bleomycin(BLM),which was composed of ginseng,cortex acanthopanasia radices(CAR),pachyna cocos Fr.and angelica at certain concentration.Methods The mutagen sensitivety test was used to detect the effect of BLM on chromatid breaks per cell from peripheral blood lymphocytes of 20 healthy subjects.And the infuence of Chinese medical herbals on the stability of chromsome was studied.50 cells per sample were observed under microscope and then the average b/c value(chromatid breaks per cell) of every group was calculated.The all b/c values were analyzed by statistical method.Results There was obvious difference of the b/c value between BLM group and negative group(P

BACKGROUND: Cephalocervical cancer is closely related with genetic factors, but do the first-degree relatives have a higher risk for cancers? Slenderstyle acanthopanax root-bark has an anti-mutation chromosome stabilizer, can it enhance the anticaner ability of the first-degree relatives? OBJECTIVE: To study the genetic factor of cephalocervical cancer and antimutagenic effect of slenderstyle acanthopanax root-bark.DESIGN:A controlled experiment with human peripheral blood as the sample.SETTING: The Department of Medical Genetics of the Basic Medical Science School, and the Department of Otolaryngology of the First Hospital of Jilin University; The University of Warwick, UK.PARTICIPANTS: The subjects were taken during the period of October 2001 to March 2002. The patients with cephalocervical tumor and their first-degree relatives were all from the Department of Otolaryngology,FirstHospital of Jilin University, and healthy group were well-being blood devoting volunteers from Changchun City Central Blood Bank. There were group( n = 50) included 25 males and 25 females who were healthy blood patients group( n =30) were composed of 22 males and 8 females who did first-degree relative group(n=30) consisted of 19 males and 11 females. They were the first-degree relatives of patients with carcinoma of larynx and carcinoma of nasopharynx. Except for the family history of cancer,they themselves were all healthy. Informed consents were obtained from all of them.METHODS: The peripheral blood was collected as the sample and the lymphocyte culturing was performed. The culture cycle was 72 hours and bleomycin(BLM) (15 mL) was added into it at the 67~ hour, also the slenderstyle acanthopanax root-bark(SARB) (800 mg/L) was added into the antimutagenesis experiment. The cells were collected after culturing for another 72 hours. The conventional method was used for slide preparation. The slides were stained with Giemsa solution without banding. Choosing the proper objective and observing the numbers of chromatid breaks. The numbers of chromatid breaks were converted into the numbers of chromatid breaks per cell (b/c value). Namely, b/c value equals to the quotient, the number of chromatid break divided by the number of the cell observed in the slide.MAIN OUTCOME MEASURES: The number of chromatid breaks per cell (b/c value).RESULTS: All the 110 cases in the 3 groups entered the stage of result It was lower in the control group than that in the patients group and first-degree relatives group(0.16 ± 0.06, 0.48 ± 0. 14, 0.42 ± 0. 12, P ＜0.01). There was no significant difference in b/c value between the paparison between b/c value induced by combined SARB with BLM and only BLM was performed: The b/c value of former is significantly lower than the latter (0.48±0.14,0.15 ±0.08,0.42±0.12, 0.17±0.11,P ＜ 0.01).CONCLUSION: The first-degree relatives of the patients with cephalocervical cancers should be classified as tumor high-risk group. SARB as a chromatid stabilizer has an obvious inhibitory effect on b/c value of the patients induced by BLM and that of the first-degree relatives.

Objective To evaluate the diagostic value of hypersensitive C-reactive protein(hs-CRP),β2-microglobulin(β2-MG) and cystatin C(Cys-C)tests in diabetic nephropathy(DN)of early stage.Methods The turbidimetric immunoassay was adopted to determine serum hs-CRP,β2-MG and Cys-C concentrations in type 2 diabetic patients,including 100 cases with DN of early stage (DN group),50 cases without DN(NDN group)and 100 cases healthy controls(control group).Results Serum hs-CRP,β2-MG and Cys-C concentrations in DN group were significantly higher than that in control group and NDN group(P <0.05).Conclusion Hs-CRP,β2-MG and Cys C are sensitive indicators in the diagosis of DN.The combined determination of the three indicators im-proves the sensitivity of early DN diagnosis and is useful for monitoring the development of DN in early stage.

Objective:To study the effects of glucosamine(GlcNH2) on immune function in mice.Method:The effects of GlcNH2 on murine proliferation of splenocytes were carried out in vitro.After feeding mice by GlcNH2,the phagocytotic functions of mononuclear macrophage,murine delayed type hypersensitivity(DTH) caused by sheep red blood cells(SRBC),the ability of antibody production(tested by HC50),and the index of immune organs(thymus and spleen) were deteimined in vivo.Results:GlcNH2 could promote the proliferation of splenocytes,phagocytotic functions of mononuclear macrophage,DTH,the ability of antibody production and the index of immune organs.Conclusion:Glucosamine can enhance immune function in mice such as cellular immunity,humoral immunity and non-specific immunity.