Objective To analyze the use of serum pepsinogen(PG) and Helicobacter pylori(Hp)-IgG antibody in the screening of atrophic gastritis.Methods A total of 222 patients were divided into two groups according to the gastroscopy results:159 cases in observation group(atrophic gastritis) and 63 cases in control group(non-atrophic gastritis).Patients in observation group were divided into gastric antrum group(50cases),gastric body group (71 cases) and full stomach multifocal group (3 8 cases) according to shrinking parts.The serum PG Ⅰ and PG Ⅱ was determined by enzyme linked immunosorbent assay method,and PGR (PG Ⅰ / PG Ⅱ) was calculated.The serum Hp-IgG antibody was examined by qualitative analysis.Results The serum PG Ⅰ and PGR was (57.82 ± 23.15) μ g/L,4.41 ± 1.82 in observation group,which was lower than that in control group[(125.04 ± 29.36) μ g/L,10.10 ± 2.01],and there was significant difference (P ＜0.01).The positive rate of the serum Hp-IgG antibody was 86.16％(137/159) in observation group,which was higher than that in control group [53.97％ (34/63)],and there was significant difference (P ＜ 0.01).There was significant difference in the serum PG Ⅰ and PGR between gastric antrum group and gastric body group,full stomach multifocal group (P ＜ 0.01).There was no significant difference in the serum PG Ⅰ and PGR among different atrophy degree in gastric antrum group(P＞ 0.05),but there was significant difference in the serum PG Ⅰ and PGR among different atrophy degree in gastric body group and full stomach multifocal group (P ＜ 0.01).Conclusions The serum PG Ⅰ and PGR and Hp-IgG antibody is related to atrophic gastritis.They are helpful to the screening of atrophic gastritis.

Objective To study the risk factors of preschool recurrent wheezing in Anhui area. Methods The clinical data from 816 children were collected through a questionnaire. The risk factors of preschool recurrent wheezing were investigated by logistic regression analysis. Results Preschool recurrent wheezing was associated with premature delivery, caesarean section, early weight gain(0 ~ 3 m), food allergy, allergic rhinitis, eczema, asthma or allergic rhinitis history of parents, passive smoking, viral infection and mycoplasma infection. The logis-tic regression analysis showed that premature delivery, early weight gain(0 - 3m), eczema, asthma or allergic rhi-nitis history of parents, passive smoking, viral infection and mycoplasma infection were the risk factors of preschool recurrent wheezing(P < 0. 05). Conclusion Premature delivery, early weight gain(0 - 3m), eczema, asthma or allergic rhinitis history of parents, passive smoking, viral infection and mycoplasma infection are the risk factors of preschool recurrent wheezing.

Streptococcus pneumoniae( SP) is the leading pathogenic bacteria of invasive bacterial infec-tions in children. It can cause some life-threatening diseases such as pneumonia,meningitis and sepsis. Strepto-coccus pneumoniae frequently colonizes the upper respiratory tract. It is essential to know the host immune re-sponse during the infection. This paper reviews antigenic structure of SP,pneumococcal conjugate vaccine and pneumococcal virulence factors,especially focuses on the immune response including the effect of innate immu-nity,macrophage,neutrophil and T-cell.

Velocity vector imaging (VVI) is a promising and relatively new noninvasive method of assessing wall movement and flexible features of vessels,being able to qualitatively, quantitatively, accurately and intuitively assess mechanical characteristics of vascular wall movement. VVI can reflect changes of characteristics of flexibility and movement of carotid artery in early atherosclerosis and plaque rotation angle. It provides a new way for the study of unstable plaque. The research and current status of clinical application of VVI were reviewed in this article.

Objective To observe the effect of the emodin thermosensitive hydrogel on collagenase in gingival crevicular fluid of patients with chronic periodontitis and to evaluate the clinical efficacy.Methods Forty patients with chronic periodontitis were selected.For each patient after scaring and root planning,the one teeth on one side in a person was assigned at the test group and treated with the emodin thermosensitive hydrogel in the pocket once a week for four weeks.The teeth on the other side were assigned as the control group,just with the primary periodontal treatment.The PLI、SBI、PD、AL、MD and content of collagenase in gingival crevicular fluid were examined at baseline,before administration and after administration four weeks.The COL-II level in GCF was detected using ELISA method.Results There were no significant differences in PLI、SBI、PD、AL、MD and content of collagenase in gingival crevicular fluid before the treatment(P ＞ 0.05).While there are some evidences that periodontal indexes dropped down and the type Ⅱ collagenase level in gingival crevicular fluid also declined after using the emodin thermosensitive hydrogel than the control group(t =3.46,4.02,4.18,3.03,2.79,4.29,all P ＜ 0.05).Conclusion Ultrasonic scaling using the emodin thermosensitive hydrogelas was more effective in reducing the type Ⅱ collagenase level in gingival crevicular fluid.And improving clinical parameters associated with periodontal health in patients with chronic periodontitis.

Adolescent ; Adult ; Antineoplastic Combined Chemotherapy Protocols ; therapeutic use ; Cytarabine ; administration & dosage ; therapeutic use ; Female ; Humans ; Leukemia, Myeloid, Acute ; drug therapy ; Male ; Middle Aged ; Prognosis ; Treatment Outcome ; Young Adult

AIM: To investigate the therapeutic effect of a new warm moist air device assisted with eyelid massage in the treatment of office dry eye (ODE).METHODS: Sixty ODE patients were recruited,and these patients were randomly divided into two groups.One group received artificial tear treatment,and the other group received a new eyelid warm moist air device combined with eyelid massage treatment.Subjects completed the ocular surface disease index (OSDI),which was followed by fluorescein tear breakup time (BUT),corneal fluorescein staining (CFS),Schirmer I test (SⅠt) and meibomian gland secretion function evaluation at baseline,and 2 and 4wk after treatment.RESULTS: In these 60 patients,48 patients(23 in artificial tear treated group and 25 in the new warm moist air device assisted with eyelid massage treated group)were positive for meibomian gland dysfunction (MGD).Compared to artificial tear treatment,the new warm moist air device assisted with eyelid massage treatment showed favorable therapeutic effect on OSDI (FGroup=41.63,P<0.01),BUT (FGroup=60.47,P<0.01) and the grade of meibum quality (FGroup=12.12,P<0.01) during 4wk treatment in this study.No significant difference was found in SIT (FGroup=0.17,P>0.05),CFS (FGroup=1.79,P>0.05) and meibomian gland expressibility (FGroup=0.68,P>0.05) between the two groups during 4wk treatment.CONCLUSION: This new eyelid warm moist air device assisted with eyelid massage has favorable therapeutic effect over artificial tear in ODE treatment.

Objective: To evaluate 2D CDUS ultrasound in estimating lesions of carotid and femoral arteries in diabetes mellitus. Methods: Forty patients were divided into 3 groups by age. We detected their carotid and femoral arteries using two dimensional and PW Doppler ultrasonography. The lesions degree were assessed according to U B 6 classification. Results: Higher incidence and more serious degree of arteries lesions occurred in diabetes mellitus than those in control group ( P 40 years old than in group ≤40 years old in diabetes mellitus ( P

Epilepsy is a group of chronic diseases characterized by recurrent and transient brain dysfunction induced by abrupt and intermittent abnormal discharge of neurons in the brain, which is difficult to be cured. Thee auricular concha are is he zone of visera in TCM auricular points, but also the innervating area of the auricular brach of the vagus nerve. Auricular acupuncture, as a special treatment, has superior therapeutic effect for epilepsy. In recent years, remarkable progress has been made in the theoretical basis and clinic application of auricular acupuncture for epilepsy, and the ear-vagus percutaneous electrical stimulation apparatus (auricular acupuncture apparatus) is developed for clinical trial researches. From the basic study to clinical research of auricular acupuncture for epilepsy, the epilepsy pathogenesis as well as the intervention pathway and clinical efficacy of auricular: experimental support and rich clinical experience for auricular acupuncture apparatus.
Acupuncture Points ; Acupuncture, Ear ; instrumentation ; methods ; Ear ; innervation ; Epilepsy ; therapy ; Humans

Female ; Humans ; Myocardial Infarction ; surgery ; Myocardial Revascularization