0.05).Conclusion IPAT sequence can gain super images in less time with more coils.IPAT sequence needs the distance between coil and checkpoint larger than 5 mm.MRI scan for vertebra just fit it.We think cutting scan time is a direct and effective method to decrease constructed defect.

Objective To explore the influence of positive psychological quality on the quality of life of rural left behind elderly. Meth-ods 356 rural left behind elderly in Bengbu and Huaibei cities of Anhui province were investigated with WHO Quality of Life-BREF (WHO-QOL-BREF), Chinese version of the Meaning in Life Questionnaire (C-MLQ), Purpose-in-Life Test (PIL) and Index of Well-Being (IWB). Results The scores of WHOQOL-BREF in physical, psychological, social relations and environment are significantly lower in the rural left behind elderly than in the norm in China (t>3.105, P<0.001). The scores of WHOQOL-BREF of the left behind elderly in rural areas signifi-cantly correlated with the sense of life meaning, life objective and subjective well being (P<0.05). The quality of life of left behind elderly in rural areas was analyzed by regression analysis, age, health status, education and other demographic variables and life goals, life sense, sense of autonomy, etc. entered the regression equation (P<0.05). The structure model analysis showed that the life meaning and purpose of life were the important factors that affected the quality of life of rural left behind old people, in which the subjective well-being played a meditational role. Conclusion The positive psychological quality of life meaning, life purpose and other positive psychological qualities sig-nificantly impact the quality of life of rural left behind elderly, and should carry out targeted mental health guidance.

Objective To explore the effect of psychological intervention on the rehabilitation of depressive patients.Methods 183 depressive patients were randomly divided into study group (n=93) and control group (n=90). The study group was given systemic psychological intervention additional to routine medicine for 12 weeks and the control group was given only medication. The efficacy was measured by Brief Psychiatric Rating Scale (BPRS), Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS).Results There is no significant difference in SDS, SAS and BPRS ratings between two groups before the intervention (P>0.05). The scores of anxiety-depression, lacking-activity, thinking-disturbance, SAS and SDS were significantly lower in the study group than in the control group 12 weeks after the intervention(P<0.05). Conclusion Psychological intervention can positively improve the rehabilitation of depressive patients.

Objective: To investigate the effects of total paeony glucoside on brain Notch signaling pathway in focal cerebral infarction rats. Methods: Stroke rats were prepared and divided into 5 groups: model group, low dosetotal peony glucoside group, medium dosetotal peony glucoside group, and high dosetotal paeony glucoside group, with 20 rats in each group. All groups received the medication for 20 days. The body weight, brain water content, cerebral infarction size, brain tissue NICD, Hes1 and Hes5 proteins and Hes1 and Hes5 mRNA expressions were measured in each group. Results: There was no significant difference in body weight before administration within these groups (P>0.05). After treatment, compared with those in the control group, the body weight significantly decreased (P<0.05); NICD, Hes1 and Hes5 significantly increased; Hes1 and Hes5mRNA significantly increased in the model group (P<0.05). Compared with those in the model group, the body weight significantly increased (P<0.05); the NICD, Hes1 and Hes5 significantly decreased; Hes1 and Hes5mRNA significantly decreased (P<0.05) in a dose-dependent manner. Conclusion: Total peony glucoside can treat focal cerebral infarction by inhibiting Notch signaling pathway in rat brain tissue.

Objective:To investigate the influential factors of mental health in rural high-school students by structural equation modeling.Methods:447 rural high-school students were tested by Mental Health test,Adolescent Self-rating Life Events Check list,Social Support Scale and Trait Coping Style questionnaire,then theoretical model were established and confirmed for the relationships of life events,social support,coping styles and mental health of rural high-school students.Results:The structural equation modeling fitted the data very well(?2/df=3.56,GFI=0.940,AGFI=0.902,NFI= 0.913,CFI=0.901,RMSEA=0.048),the theoretical model suppose was supported by the use of structural equation modeling.Conclusion:Social supports and coping styles have direct influence on mental health of rural high-school students.Life events have indirect influence on mental health through social supports and coping styles.

Animals ; Humans ; Ischemic Preconditioning, Myocardial ; MicroRNAs ; Myocardial Ischemia ; genetics ; prevention & control

Objective To explore the optimal method of qualitative and quantitative assessment of retinal neovascularization(RNV),choroidal neovascularization(CNV) and leakage from CNV. Methods Thirteen mice were randomly divided into RNV assessment group(n=7)and CNV assessment group(n=6).For RNV assessment, 3 mice were served as normal controls,and the other 4 were made into models of retinopathy of prematurity(ROP).At postnatal d16,mice in normal control group and 3 ROP model mice received intraocular injection with FITC labeled or unlabeled antibody and were sacrificed 12 h later.The retinas were flat mounted(FITC labeled antibody) or incubated with secondary antibody(unlabeled antibody) and then flat mounted.The other ROP model mouse was served as blank control.For assessment of CNV and leakage from CNV,6 mice(12 eyes) were induced into models of CNV,and were randomly divided into two groups.Seven and 14d after model establishment,mice were intraocularly injected with unlabeled antibody,and fluorescein sodium were intraperitoneally injected 12 h later.The area of CNV and that of CNV leakage were calculated. ResultsRetinas from eyes injected with FITC labeled antibody exhibited good resolution of ultrastructure of RNV,while retinas from eyes injected with unlabeled antibody showed selective staining of RNV with no background,greatly facilitating identification and quantification of RNV.Merging images of stained CNV with images of fluorescein sodium leakage from CNV revealed double labeled CNV surrounded by fluorescein that had leaked into surrounding tissues.The mean area of CNV and its leakage of d14 were significantly different from those of d 7(P

Certification ; China ; Humans ; Occupational Health Physicians

Certification ; Humans ; Occupational Health Physicians

Objective To investigate the genetic damage of human bronchial epithelial cells (HBE) caused by cigarette smoke combined with nano-TiO2.Methods 16-HBE cells were exposed to cigarette smoke extract (CSE) and nano-TiO2(mg/L) at the doses of 0 mg/L CSE+0 mg/L nano-TiO2,50 mg/L CSE+0 mg/L nano-TiO2,75 mg/L CSE+0 mg/L nano-TiO2,100 mg/L CSE+0 mg/L nano-TiO2,0 mg/L CSE+10 mg/L nano-TiO2,50 mg/L CSE+10 mg/L nano-TiO2,75 mg/L CSE+10 mg/L nano-TiO2,100 mg/L CSE+10 mg/L nano-TiO2. After 24 h exposure,HBE viability was evaluated by the methyl thiazolyl tetrazolium (MTT) assay,single cell gel electrophoresis (SCGE,comet assay) was employed to assess DNA damage,chromosomal aberration was measured by micronucleus test. Results Except the group exposed to 10 mg/L nano-TiO2,HBE viability of the other treatment groups were lower than that of the control group and Comet % of the other treatment groups were higher than that of the control group (P