1.The application of color Doppler flow imaging examination in diagnosis of liver tumor
China Medical Equipment 2016;13(5):90-92
Objective:To investigate the diagnostic value of color Doppler flow imaging(CDFI) in the diagnosis of liver tumors.Methods: UE, CEUS, and CDFI were performed in 104 patients with liver cancer who were admitted to our hospital from January 2013 to December 2014, in order to analyze the diagnostic value of three methods for liver tumor compared with the pathological results.Results: The 115 masses of the group included 97 malignant masses(84.34%) and 18 benign masses(15.66%). The diagnostic accuracy of CDFI for benign and malignant liver tumors was 55.56% and 74.23%. There was no significant difference between UE and CDFI in the diagnosis of benign liver tumors and CEUS was higher than that of CDFI and UE in the diagnosis of benign and malignant liver tumors. There was no statistical difference in the diagnostic accuracy of CDFI combined with UE and CEUS(x2=2.20, P=0.138).Conclusion: CDFI is a basic method for the diagnosis of liver tumors. The CEUS or UE can be used to improve the accuracy of diagnosis for the liver which is not typical or small lesions.
2.Th17 cell and CD4 + CD25 + Treg in iathogenesis of asthma
International Journal of Pediatrics 2012;39(2):196-198,202
Many studies have suggested that pathogenesis of asthma could no longer be interpreted merely by “Th1/Th2 balance” theory.CD4 + CD25 + Treg and Th17 cells,as well as their cytokines such as IL-10,transforming growth factor-β,and IL-17,account for asthma.CD4 + CD25 + Treg and Th17 are functionally antagonistic to each other,and also go with each other during their differentiation.Therefore,immunity-unbalance of CD4 + CD25 + Treg and Th17 is one of the most important factors that triggers asthma.Glucocorticoid has been shown to down regulate IL-17 expression by retinoic acid receptors γt signaling pathway,and regulate differentiation and function of CD4 + CD25 + Treg by inducing expression of transcription factor Foxp3,all of these are immuno-mechanisms of glucocorticoid in asthma treatment.
3.The clinical probation of new type oral MRI contrast agent D98A
Chinese Journal of Radiology 1994;0(06):-
Objective To evaluate the efficacy of D98A,a newly developed superparamagnetic oral MRI contrast agent,in the diagnosis of abdomen.Methods Plain and contrast MRI after taking 500~1000 ml D98Ain 80 patients were performed by using different field strength MR scanners,and the sequences included T 1WI,T 2WI,and fat suppressed sequences.The contrast effect,distribution,influence on demonstration of contours of abdominal organs,and side effects were studied concerning this suspension.Results It showed that this oral contrast agent had good security character,wide consideration area,low cost,good contrast effect,and high value of clinical application.The gastrointestinal tracts appeared as hypointensity on various MR sequences,and thus,made them easy to be identified.The margins of abdominal organs were easier to be located after taking the contrast,and the distinction had statistical denotation.The demonstration rate of gastrointestinal tracts was raised from 10% to 89% after using D98A.There were no side-effects in all patients. Conclusion D98A is safe and effective in facilitating the localization of the abdominal organs.It can improve the accuracy in delineating the gastrointestinal tracts and in diagnosing the lesions of abdominal organs.
4.The effect of coix seed oil on lung cancer
Journal of International Oncology 2011;38(2):139-141
Coix seed has anti-tumor effect and the anti-tumor activity composition is coix seed oil. Researches show that inducing cancer cell apoptosis and angiogenesis inhibition and regulation of the immune and analgesic function are the major roles of coix seed oil. Clinical researches prove that the effect can be increased and the life quality of lung cancer patients can be improved and the survival time can be prolonged when coix seed oil is used to treating lung cancer combined with Chemotherapy and Radiotherapy. So it is widely used in the treatment of lung cancer.
5.Clinical study of tirofiban in treatment of high-risk non-ST elevation acute coronary syndrome around perioperative period intervention
Chinese Journal of Biochemical Pharmaceutics 2014;(3):105-107
Objective To explore the clinical efficacy of tirofiban in treatment of patients with high-risk non-ST-segment elevation of acute coronary syndrome (NSTE ACS),in order to improve the level of treatment effect. Methods 90 cases with high-risk NSTE ACS from January 2011 to April 2013 were randomly divided into control group and observation group. The control group were received treatments of conventional aspirin,clopidogrel, anticoagulation,coronary angiography (CAG)and percutaneous coronary intervention (PCI),while the observation group were added tirofiban therapy an the basis of control group. After the treatment,the differences of cardiovascular adverse events,thrombolysis in myocardial infarction (TIMI)flow grade and complications in both two group were observed and compared. Results There were significant differences in major adverse cardiovascular events in the distal vascular blockage,surgery without reflux,recurrent angina and myocardial infarction and post-PCI TIMI flow grade 2 and 3 (P<0.05),but not in bleeding complications,TIMI flow grade 0 and 1 before and after PCI treatment. Conclusion Tirofiban is safe and effective in treatment of high-risk NSTE ACS in interventional procedures. It can improve TIMI flow, increase tissue perfusion and reduce postoperative complications.
6.Research on College Students' Mental Health Level
Chinese Medical Ethics 2017;30(4):504-508
Objective:To explore the mental health change among college freshmen,taking the age of late 1980,early 1990 and 1995 as the Qividing years.Method:We randomly selected 300 participants (total 900) in each period from the 2006-2015 year coollege freshman newborn psychological assessment data in a university in Xi'an.The data was analyzed by T-test and variance analysis.Results:There were significant differences among gender,family structure and the local institution in both China college students mental health scale (CCMHS) and college students' Psychological Adaptation (CCSAS).The level of mental health and psychological adaptation of college students after 95 is better than the students at the end of 80 and beginning of 90.Conclusion:College students' mental health and psychological adaptation level showed a trend of rising.But it still needs to carry out sexual mental health knowledge lecturer aiming at the existence of psychosexual disorder,continue to strengthen the newborn adaptability education and activities,establish required course of mental health and popularize mental health knowledge.
7.Design and manufacture of a novel orientation device of elbow rotation center
Chinese Journal of Orthopaedic Trauma 2016;18(7):616-620
Objective To report the design and manufacture of a novel orientation device of elbow rotation center.Methods The anatomical data of distal humeral elbow were obtained from 3 reports on the anatomy of the distal humerus retrieved from CNKI from 2004 through 2014.Software UGS.0 NX,CAD/CAM animation and video were used to design the 3D model of our novel orientation device of elbow rotation center.The glass fiber physical model of the device was manufactured using 3D printing technology.Five healthy volunteers were recruited for a simulated surgery experiment to test the efficacy and accuracy of the device,including 4 males and 1 female,from 25 to 36 years of age.Results No change was observed before and after the device was disinfected regarding the length (129 mm),width (116 mm) or height (215 mm),or other shapes.Satisfactory X-ray images of the elbow were obtained in the 5 volunteers.The fluoroscopy frequency required ranged from 6 to 11 times,averaging 8.2 times.The time needed for orientation ranged from 442.2 to 554 seconds,averaging 489.2 seconds.Conclusions Our self-designed orientation device can be used to accurately position and orientate the rotation center of elbow joint,showing its reasonable design.Glass fiber materials can be used to manufacture our orientation device.
8.The Effect of Diabetic Health Education on Improving the Diabetic Knowledge Score and Glucose Metabolism
Bin YAO ; Jianjuan LI ; Guoliang HU
Journal of Chinese Physician 2000;0(12):-
Objective To observe the effects of diabetic health education on improving the diabetic knowledge score(DKS) and glucose metabolism.Methods 119 diabetic patients were randomly divided into two groups,in addition to conventional therapy,the experimental group of 64 cases received one month diabetic health education,however,the control group of 55 cases was only treated with conventional therapy.Drug therapy of all patients was not changed during the observation.The changes of fasting blood glucose(FBG),post-prandial two-hour blood glucose(PBG),glycosylated hemoglobin(HbA 1c),diabetic knowledge score were detected.Results FBG,PGB,diabetic knowledge score were significantly improved after diabetic health education in experimental group(P0 05).Conclusion Diabetic health education can improve the DKS and glucose metabolism in diabetic patients.
9.Comparison of hemodynamics after on-pump and off-pump in the patients undergoing coronary artery bypass graft
Bin YAO ; Shangyi JI ; Zhiyong HUANG
Chinese Journal of Anesthesiology 1996;0(08):-
0.05), while CO, CI in both groups and SVI in OPCAB group increased significantly ( P 0.05). SVRI and PVRI were significantly lower in OPCAB group than those in CABG group (P
10.The comparison among three assays for detection of microalbuminuria
Xiangzhong OU ; Wanping DENG ; Bin YAO
Chinese Journal of Practical Internal Medicine 2006;0(21):-
Objective To evaluate the consistency and diagnosis importance among three assays of Micral-Test strip,DCA 2000 analyzer and radioimmunoassay.Methods A total of 133 random urine samples of patients with diabetes were determined positive or questionable positive by Micral-Test strip,from whom urine samples within 8 hours during the nighttime were also collected.Both the two urine samples were determined by three assays for detection of microalbuminuria.Results(1)The value of Alb and AER determined by radioimmunoassy was significantly lower than that by DCA2000 analyzer,of which the sensitivity and specificity is 100%and 86.2%,?=0.812.(2)According to the reading scales of Micral-Test strip,the area under ROC curve(AUC)of random and 8 h urine samples were 0.900 and 0.934 respectively.(3)The AUC of random ACR and Alb was 0.952 and 0.923.The AUC of 8h urine ACR and Alb were 0.965 and 0.958.Conclusion The diagnosis importance among three assays is all dependable.Micral-Test strip is convenient for screening.ACR cannot substitute for AER as a diagnosis standard.And the value determined by DCA 2000 analyzer is more precise than that of radioimmunoassay.