1.Application of Alternate Electroacupuncture Waveforms in Treatment of Peripheral Facial Paralysis
Chinese Journal of Rehabilitation Theory and Practice 2007;13(7):655-656
Objective To study the application of waveforms in treatment of peripheral facial paralysis with electroacupuncture. Methods 66 patients with peripheral facial paralysis were divided into two groups: treatment group (34 cases) and control group(32 cases). All the patients were acupunctured at the similar points with electroacupuncture, while the disperse-dense wave and the discontinuous wave were used successively in the treatment group, and the disperse-dense wave was used alone in the control group. Results There were significant differences between the two groups in the total effective rate and the days for cure (P<0.01). Conclusion The effect of alternate disperse-dense wave and discontinuous wave is superior to that of disperse-dense wave alone in electroacupuncture treatment for peripheral facial paralysis.
2.Effect of Acupoint Injection with Nerve Growth Factor on Ramsay Hunt Syndrome
Chinese Journal of Rehabilitation Theory and Practice 2012;18(6):586-587
Objective To observe the clinical effect and the incidence of neuralgia of acupoint injection with nerve growth factor onRamsay Hunt syndrome. Methods 65 patients with Ramsay Hunt syndrome were divided into treatment group (n=33) and control group(n=32). All the patients were treated with the anti-virus and glucocorticoid medicine, and were acupunctured at the similar points with electroacupuncturewith the disperse dense wave. The treatment group was injected with mouse nerve growth factor at the acupoints. 2 days offevery 5 times, 10 times as a course for 2 courses. The treatment effect and the incidence of sequelae neuralgia after 3 months were compared.Results The total effective rate of treatment group (93.9%) was significantly higher than control group (71.9%) (P<0.01). The incidenceof sequelae neuralgia of the treatment group (6.3%) was significantly lower than the control group (26.7%) (P<0.01). ConclusionAcupoint injection of mouse nerve growth factor can improve the efficacy and reduce the incidence rate of sequelae neuralgia in patientswith Ramsay Hunt syndrome.
3.Study of procalcitonin and C-reactive protein in predicting enterog-enous bacterial infection among diarrheal patients after irinotecan chemotherapy
Chinese Journal of Clinical Oncology 2015;(7):382-385
Objective:To investigate procalcitonin and C-reactive protein levels in diarrheal patients who underwent irinotecan che-motherapy. Methods:Procalcitonin and C-reactive protein were detected among 85 diarrheal and 63 non-diarrheal patients after irinote-can chemotherapy. Results:According to WHO classification, patients without diarrhea are classified as grade 0, whereas patients with diarrhea can be classified as gradesⅠ-Ⅳ. In grades 0,Ⅰ,Ⅱ,Ⅲ, andⅣpatients, the levels of procalcitonin were 0.29 ± 0.17, 0.30 ± 0.18, 0.36 ± 0.20, 1.24 ± 0.22, and 2.15 ± 0.26 ng/mL on the second day, respectively. However, on the fourth day, the procalcitonin lev-els were 0.28 ± 0.15, 0.30 ± 0.14, 0.34 ± 0.18, 2.00 ± 0.22, and 2.40 ± 0.28 ng/mL, respectively. Moreover, in grades 0,Ⅰ,Ⅱ,Ⅲ, andⅣ, the levels of C-reactive protein were 6.06 ± 1.85, 6.12 ± 1.16, 6.20 ± 1.68, 22.62 ± 4.55, and 31.26 ± 5.23 mg/L on the second day, respectively. On the fourth day, the C-reactive protein levels were 5.80 ± 1.82, 5.94 ± 1.14, 6.15 ± 1.55, 30.52 ± 4.74, and 38.67 ± 5.68 mg/L, respectively. No significant difference was found between the procalcitonin and C-reactive protein levels of stagesⅠandⅡpa-tients (P>0.05), but a significant difference was found between stagesⅠ, andⅡpatients and stagesⅢandⅣpatients (P<0.05). Con-clusion: Monitoring levels of procalcitonin and C-reactive protein may be helpful in the early evaluation of the severity of diarrhea. This process has prognostic effect and can be used to assess whether patients have enterogenous bacterial infection. Monitoring the lev-els of these proteins has certain clinical value and can be used to guide early anti-infection therapy.
4.Skeletal myoblast transplantation
Chinese Journal of Tissue Engineering Research 2008;12(18):3597-3600
Myoblast transplantation has been carried out for a certain period,but its efficiency in repairing inherited myopathy or severe muscular injury is not satisfactory.The improvements in myoblast culture,transplantation approach,recipient and cell preparation before transplantation,scaffold material and its selection,and body immunity can positively influence transplantation efficacy,and improve recipient function.In addition,these improvements influence the prospect of myoblast transplantation or cell-mediated gene therapy.
5.Lymph Node-Targeted Chemotherapy for Gastric Carcinoma
Chinese Journal of Bases and Clinics in General Surgery 2003;0(05):-
Objective To introduce the recent studies about the lymph node-targeted chemotherapy for gastric carcinoma. Methods The literatures on the lymph node-targeted chemotherapy for gastric carcinoma in recent years were collected and reviewed. Results The lymph node-targeted chemotherapy for gastric carcinoma was effective because it couled improve the drug concentrations in regional lymph node. Conclusion As a part of multiple treatments for gastric carcinoma, lymph node-targeted chemotherapy will be further developed.
6.Correlations of Serum Markers of Hepatitis B Virus,HBV DNA Load and Liver Function
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong 2017;46(2):214-219
Objective To investigate the correlations of serum markers of hepatitis B virus,HBV DNA load and liver function indexes[alanine aminotransferase(ALT)and aspartate transaminase(AST)]in the peripheral blood.Methods Clinical data of 483 patients who were diagnosed with chronic hepatitis B and treated between March 2014 and March 2016 in Tongji hospital were retrospectively analyzed.The serum markers of hepatitis B virus were quantitatively detected by chemiluminescent microparticle immunoassay.Serum HBV DNA load was measured by real-time fluorescence quantitative PCR,and ALT and AST by continuous ultraviolet monitoring.Results There was no correlation between the HBsAg content and HBV DNA load or the rates of abnormal ALT(>41 U/L)and abnormal AST(>35 U/L)(P>0.05).The HBeAg content was not correlated with HBV DNA load and the rates of abnormal ALT(P>0.05),but weakly with the rate of abnormal AST(r=0.21,P<0.01).Although the anti-HBe content was not correlated with the rate of abnormal ALT(P>0.05),it was weakly related to HBV DNA load and the rates of abnormal AST(r=0.16,P<0.05;r=0.19,P<0.01).The anti-HBc content had weak correlations with HBV DNA load,the rates of abnormal ALT and abnormal AST(r=0.25,P<0.01;r=0.29,P<0.01;r=0.29,P<0.01).The logarithm value of HBV DNA load was weakly positively correlated with ALT and AST(r=0.24;r=0.29).Conclusion Quantitative detection of both serum markers and the DNA of hepatitis B virus can complement each other,and when combined with detection of liver function indexes,it will help understand the damage of liver tissue.
7.Size changes of erythrocytes infected with Plasmodium malariae in thin pe-ripheral blood smears
Chinese Journal of Schistosomiasis Control 2016;28(5):586-588
Objective To explore the size changes of erythrocytes infected with Plasmodium malariae,so as to improve the basic?level experimenters’microscopy capabilities for P. malariae identification in thin blood smears. Methods The micro?scopic features of erythrocytes infected with P. malariae in thin peripheral blood smears were observed,and a microscope image processing software was used to measure and analyze the diameter changes of the erythrocytes infected with P. malariae. Re?sults The diameter of erythrocytes infected with P. malariae decreased significantly compared with that of the normal erythro?cytes. The three parameters in this study:the diameter of erythrocytes,the value of diameter variation,and the ratio of diameter variation varied at different developmental stages of P. malariae,and the differences were statistically significant(all P<0.01). The variances of the three parameters grouped by different cases or different developmental stages in different cases were ana?lyzed,all showing statistically significant differences(all P<0.01). Conclusion All the developmental stages of P. malariae will cause the decrease of the diameters of infected erythrocytes in peripheral blood smears,but the influence on the diameter of erythrocytes,value of diameter variation,and ratio of diameter variation varies at different developmental stages in different cases.
8.Study Progress on Chronic-toxic Effects of Methyl Parathion
Journal of Environment and Health 1989;0(06):-
Pesticides plays an important role in the history of agricultural development,but the health hazards and environmental pollution problems are attracting increasing attention. Methyl parathion is one of the most widely used pesticides,its threat to human health caused increased emphasis. This paper introduced the chronic toxicity of methyl parathion to various systems such as the nervous system,endocrine system,immune system and reproductive system.
9.Clinical Analysis of Xerostomia in Patients With Head and Neck Cancer After Radiation Therapy
Chinese Medical Equipment Journal 1993;0(06):-
Objective To study the influence on xerostomia of radiotherapy in treatment of head and neck cancer.Methods 82 cases with head and neck cancer from August 2005 to January 2006 were analyzed retrospectively.All patients were asked about their xerostomia at the end of every week.Then xerostomia and xerostomia-related problems were analyzed.Results There were obvious difference in the incidence rate of xerostomia( ?2=26.24,P 0.05).Conclusion During radiotherapy,acute radiation xerostomia may happen.The rate of it is different.depending on the radiation dose to be accepted while not on the age.
10.Various stent materials for intracranial arteriostenosis: Complication prevention and application development
Chinese Journal of Tissue Engineering Research 2010;14(9):1685-1688
OBJECTIVE:To explore the treatment effect and complication prevention of various stent materials for intracranial arteriostenosis.METHODS:A computer-based online search of Science Direct and Ei database (1998-01/2009-10) was performed for English articles with the key words of "intracranial arteriostenosis,stent placement" In addition,CNKI and CBM database (1998-01/2009-10) were searched for related Chinese articles with the same key words in Chinese.Moreover,related works were manually searched.Studies regarding various stent materials for intracranial arteriostenosis were included,including basic and clinical experiments.RESULTS:Multicenter studies of worldwide show that stent implantation displays obvious advantages in treating carotid artery stenosis compared with carotid endarterectomy.Recently,with developing of balloon and stent compliance,as well as stent technology,and application of various novel materials and cerebral protection device,stent has become a safe and effective therapy for intracranial arteriostenosis.However,complications following stent implantation,such as restenosis,ischemic stroke,cerebral hemorrhage hypertransfusion syndrome,and cerebral angiospasm,limit its application.CONCLUSION:The safety and efficacy of intracranial stent implantation remains validation of multicenter and perspective studies.High incidence of restenosis following stent implantation requires further improvement.