BACKGROUNDS: Abdominal X-ray findings of destructive acute pancreatitis are usually similar with intestinal obstruction x-ray sign. GOAL: The main goal of this study is detecting X-ray findings of pancreatitis depend on type of pancreatitis and location of the pathological abnormality. OBJECTIVES: 1. Determining pancreatitis x-ray findings depend on types of pancreatitis and pathologic abnormalities location. 2. Determining radiologic features of chronic pancreatitis MATERIALS AND METHODS: From2012 to 2014, 45 patients’ x-ray finding of pancreatitis have been analysed (31 patients with acute pancreatitis and 14 patients with chronic pancreatitis). All patients have diagnosis by clinical symptom, laboratory tests, ultrasound, celiacography, CT, MRI, ERCP, MRCP,citology and biopsy. RESULTS: X-ray findings of pancreatitis are associated with type of acute pancreatitis and location of pathologic abnormalities in the pancreas. CONCLUSION: 1. Patients with pancreatic tail swelling and deformity (acute pancreatitis), whose chest radiograph shows elevation of left hemi-diaphragm. Arka signs are seen level of L2 ,right side of the L2-L3, and stomach and upper part of the small intestine filled with gas, these recognized radiographic signs are associated with head of the pancreas destruction, which is caused by acute pancreatitis. 2. In our study, commonly recognized radiographic signs associated with chronic pancreatitis include with ascending colon and hepatic flexure are filled with gas, right part of transverse colon spasms, stomach and upper part of the small intestine filled with gas and small calcification in the pancreas

Background Abdominal ultrasonography assesses the size, echotexture, shape, contour and adjacent structures of pancreas. Goal The goal of our study is to determining ultrasonography criteria of acute and chronic pancreatitis and developing algorithm of differential diagnosis. Objectives 1. To determine ultrasonography criteria of acute and chronic pancreatitis 2. To develop algorithms of differential diagnosis of acute and chronic pancreatitis Material and Method During the study period, 81 patients with acute pancreatitis, 66 patients with chronic pancreatitis has examined byultrasonography in Reference centre on Diagnostic Imaging named after R. Purev state laureate, people’s physician,hoporary professor of the State III nd Central Hospital,AchtanClinicalHospi tal,Central Clinic of Ulaanbaatar railway and Hepatological clinic centre of traditional medicine Result 48 (59.3%±5.5) patients with acute pancreatitis had reported pancreatic swelling /Exudative pancreatitis/, 18 (22.2%±466) had acute hemorrhagic pancreatitis, 15 (18.5%±463) had necrotizing pancreatitis. Conclusions 1. Determined ultrasonographic criteria of acute and chronic pancreatitis 2. Acute and chronic pancreatitis has diagnosed by ultrasonographic criteria and developed differential diagnosis algorithm.

The age of 12 permanent molars 6 source formation, teeth grow footnote rows of teeth to catch various dental routine dental transferred under the grip. Operations and development perspective 6th gear teeth with dental row a key role to ensure a balance between teeth. This is the dental caries and other reasons deviations in adjacent teeth, jaw bones flaw, merge lengthen teeth, chewing on a toothpick footnote central line switch the arc fault is the key basic conditions.We study in MNUMS Dental school 2013-2014 customers in 1:1 ratio unfolded taken x-ray studied biological life in a sample of pictures of children over the age of 12 . Picture Image J 1.49b measurement statistics into the application development with SPSS 17.0.Biological age of 12 years old 6th gear teeth grow reach during our study involved 56 children , 18 ( 32.14 %) were taken in 6th gear teeth .Therefore, the 6th gear to be controlled from the start grow regular dental caries prevention laces jaw bone and teeth abnormalities shows the importance of the development.

Introduction: Hepatocellular carcinoma(HCC) is the 6th most common cancer inthe world, but the first most commoncause of cancer death in Mongolia. Thereis no universally accepted consensuspractice guidelines for HCC owing to rapiddevelopments in new treatment modalities,the heterogeneous epidemiology and clinicalpresentation of HCC worldwide.Methods and Materials: This study wasconducted in the department of generalsurgery of Second Central Hospital ofMongolia between 2015 and 2016 on a totalof 36 patients with hepatocellular carcinoma.Results: The average of operationtime is a 132.2 min, the hospital stay 18.2days. Postoperative bleeding was 2.7% (1),encephalopathy 5.4% (2), wound infection5.4% (2), and incisional hernia 8.1% (3).There were not bile leak during 30 dayspostoperative day.Conclusion: Postoperative complicationis a comparable to different researcher.There were no death within first month.

Background and Aims: Hepatocellular carcinoma (HCC) is a common cause of cancer related death in Mongolia. Early diagnosis is the very important management to increase successful treatment and survival rate. Glypican-3 (GPC3) protein is highly expressed in hepatocellular carcinoma (HCC) tissue and in serum of HCC patients. Recent studies have been conducted and suggested as a diagnostic biomarker for detecting HCC in the early stage. Therefore, we investigated the diagnostic value of the serum GPC3 level and compared it to the alpha-fetoprotein (AFP) level as a diagnostic biomarker of HCC. Methods: We enrolled a total of 90 participants and divided into 3 groups with HCC (30), with liver cirrhosis (LC/30) and healthy (30) as the control group (30). GPC3 and AFP serum (sGPC-3, sAFP) levels were measured using commercially available enzyme-linked immunosorbent assay kits. The diagnostic accuracy was analyzed using the receiver operating characteristics (ROC) curve and estimated sensitivity and specificity of each biomarker. Results: sGPC3 was significantly elevated in the HCC group as compared to liver cirrhosis and healthy subjects (658±138.2 pg/ml, 378±25.5 pg/ml, 356.3±29 pg/ml) respectively. sGPC-3 sensitivity was 96.6% and specificity was 100%. The area under the ROC curve (AUC) for GPC3 was 0.999 (0.996- 1.0).
In comparison, the mean of AFP was significantly higher in HCC (16.9±11.7 ng/ml) than in LC (6.7±7.6 ng/ml) and in healthy subject (3.3±2.1 ng/ml) and AFP sensitivity was 43,3 %, specificity was 95 % with an AUC of 0.808 (0.696- 0.921).
The combination of GPC-3 with AFP achieved the highest sensitivity (97.1%) and specificity (97%). Conclusion Serum GPC3 has a higher sensitivity than AFP for the early diagnosis of HCC. Combination of two markers showed greatest diagnostic accuracy.

Research of function of vitamin D on immune system has been studying since the study revealed that vitamin D receptor is expressed on the surface of the immune cells. 1,2-dihydroxyvitamin D3 [1,25(OH)2D], physiologically active form, can be generated through hydroxylation of 25-hydroxyvitamin D3 [25(OH)D], inactive form of vitamin D, in a liver, connecting with specific VDR make biological action. Vitamin D make different biological actions depends on connecting with different immunological cells. Some studies indicated that Vitamin D plays pivotal role in antibacterial innate immune responses through regulating reaction of the main cells as macrophages and dendritic cells. Moreover, calcitriol, the active form of vitamin D, is connected with VDRE, modulates the innate immune response through directly inducing expression of catelicithin and β-defensin as antimicrobial peptides, reducing secretion of IL-1b, IL-6, TNF-a, RANKL, COX-2 as proinflammatory cytokines and increasing production of IL-10, an anti-inflammatory cytokine. Vitamin D plays in proliferation and differentiation of T and B cells and regulates the activities of over 500 genes. Vitamin D differently impacts on per se stages of T cells’ proliferation. Vitamin D indirectly mitigates the differentiation from immature B cells to plasma B cells while it directly impacts on regulation of overloaded production of antibodies in plasma B cells. In conclusion, vitamin D modulates the innate- and adaptive immune response through regulation on activation of APCells, proliferation and differentiation of immune cells, secretion of some antibacterial peptides.

Introduction: Air pollution has become one of the major problems in socio-economic and health issues in Mongolia. Among the various hazards of particulate matter (PM) pollutants, microorganisms in PM2.5 and PM10 are thought to be responsible for various allergies and for the spread of respiratory diseases. Recent studies have shown that PM2.5 particles can cause chronic heart failure, heart arrhythmias, and strokes, as well as lung damage, cirrhosis, inflammation, cancer, cardiovascular disease, and metabolic disorders. Furthermore, some studies have concluded that PM2.5 particles in the environment are a risk factor for gastrointestinal, liver, colon, and lung cancer as well as it affects the growth and metastasis of various cancer cells caused by other factors. In our country, the health effects of air pollution and the relationship between the pathogenesis of cancer research are scarce. Therefore, the study of the effects of PM2.5 particles on cancer cell proliferation, migration (metastasis) can provide a significant role for cancer treatment, diagnosis, and prevention. Purpose: Determining the effects of PM2.5 particles on cancer cell proliferation, migration (metastasis) in in-vitro Material and Methods: A human liver cancer cell line (HepG2), human gastric cancer cell line (AGS) were obtained from the central scientific research laboratory in the Institute of medical sciences. HepG2, AGS cells were seeded at a concentration of 1*105 cells/mL in a culture flask and cultured in RPMI-1640 medium supplemented with 10% FBS, 1% antibiotic mix (penicillin, streptomycin) in a humidified atmosphere of 5% CO2 at 37 °C. The cytotoxic effect of PM 2.5 in AGS, HepG2 cells were evaluated by MTT, CCK8 assays. AGS, HepG2 cells were incubated in 96 well plates for 24h then treated with different concentrations (0, 5, 10, 25, 50 and 100 μg ) of Bayankhoshuu, Buhiin urguu, and Zaisan samples for 24h, respectively. Results: Concentrations of 10, 25, and 50 μg/ml of samples collected from the Bukhiin urguu and Zaisan in March increased HepG2 cell growth, while doses of 25, 50 μg/ml of samples collected from Bayankhoshuu in March and December increased HepG2 cell growth. Therefore, concentrations of 25 and 50 μg/ml of samples collected from Bayankhoshuu in March increased AGS cell growth, while concentrations of 25, 100 and μg/ml of samples collected in December increased AGS cell growth. However, no cytotoxic effect was observed in the sample collected from Zaisan in March, whereas the PM2.5 sample enhanced AGS cell growth in dose dependent manner in December.(p <0.05) Conclusion High levels of heavy metals were detected in samples collected in December from Bayankhoshuu, Bukhiin urguu and Zaisan of Ulaanbaatar. Concentration of 25 μg/ml of samples collected from the Bukhiin urguu and Zaisan in March increased HepG2 cell growth. Concentrations of 25 μg/ml of PM2.5 collected from three regions around Ulaanbaatar increased HepG2 and AGS cell migration.