OBJECTIVETo explore the influence of positional change speed on the recovery rate and discomfort degree of the patients with benign paroxysmal positional vertigo.METHODSPatients with detailed records from September 2012 to September 2015 were reviewed. 358 patients were divided into quick maneuver (<2s) and slow maneuver (5-10 s) groups randomly based on the time of changing position. The maneuver was done by the same doctor. The discomfort degree during the maneuver was assessed by the visual analog scale.RESULTSThe effective rate of the quick and slow maneuver group is 97.7% and 97.2% respectively, there is no significant differences between the groups (P>0.05). The VAS is 7.70±3.95 and 5.18±3.56 respectively in the quick and slow maneuver group, there is significant differences between the groups (t=3.38,P<0.05).CONCLUSION Positional changing speed does not influence the recovery rate of the BPPV, while the slow maneuver can reduce the discomfort degree.

Humans ; Otolaryngology ; Tinnitus

The obstruction of OSAHS patient is not limited to a single level. These blockages of multiple sites trend to influence each other and participate in a complex process. To date, the determination of obstruction is often depends on empirical judgment of clinician. However, it is a key issue to find out which level of obstruction is most significant. The article will focus on the commonly used values in laboratory examinations and their relationship with AHI. Based on the existing work, we decide to make a comprehensive analysis of their predictive value.
Humans ; Predictive Value of Tests ; Sleep Apnea, Obstructive ; diagnosis

OBJECTIVE To investigate the incidence rate of nasal septum fracture and it's influence on the effect of nasal bone reduction. METHODS Retrospective analysis of 212 cases of nasal fracture compared with nasal septum deviation were carried out. Among these cases 112 treated with nasal bone reduction only was called group A; the other cases were treated with nasal reduction concomitantly with septoplasty. Among them 58 cases were diagnosed with nasal septum fracture, it was called group B; 42 cases were diagnosed with nasal septum deviation, it was called group C. The postoperative nasal deformity rate was assessed, and the intraoperative findings of nasal septum contrast with preoperative CT diagnosis was analysed. RESULTS Three months after the operation, 27 cases (24.1%) of nasal deformity were found in group A; 9(9.0%) cases of nasal deformity were found in group B+C; septum fracture was found in 58 cases (100%) in group B and 30(71.8%) cases in group C introperatively. The diagnosis rate of nasal septum fracture by CT was 58.0%, while it's incidence rate was 88.0%. CONCLUSION More nasal septum fractures were observed introperatively than CT findings, and septoplasty concomitantly with nasal bone reduction can obviously reduce the rate of nasal deformity.

OBJECTIVE: To report the experience of canalplasty in treatment of stenosis or atresia of the external auditory canal. METHOD: A retrospective review was performed on 10 patients (10 ears) that underwent canalplasty. The lesions located in bony segment in 1 case, cartilaginous segment in 3 cases, both in cartilaginous and bony segments in 6 cases, in which 4 cases accompanied with the middle ear diseases. All patients received the canalplasty surgery, and tympanoplasty was applied simultaneously if the patient had otitis media. RESULT: Follow-up was conducted for 8-50 months respectively, 8 of the external auditory canal was wide and tympanic membrane gained a good shape, 2 case had stenosis or atresia reoccurrence after the operation. CONCLUSION Appropriate approach and elimination of the lesions thoroughly are key points for the canalplasty.
Adult ; Aged ; Constriction, Pathologic ; surgery ; Ear Canal ; abnormalities ; surgery ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Treatment Outcome ; Young Adult

OBJECTIVE: To assess the treatment outcome after endoscopic sinus surgery (ESS) in patients with recurrent sinusitis and to research which factors could influence the clinical outcome. METHOD: Endoscopic sinus surgery was performed in 55 patients. The clinical outcome and epithelization of mucosa after ESS were evaluated by Chinese ENT Association criteria. RESULT: The total cure rate was 81.82%, effective rate was 92.73%. The mean period of epithelization after operation was 13.2 weeks. No serious complication occurred. CONCLUTION The treatment efficacy can be greatly improved by the normative combined therapy which include the standard and orderly perioperative treatment ,the overall shape and nasalization of nasal cavity, postoperative follow-up and clearing cav ity after ESS.
Adult ; Aged ; Combined Modality Therapy ; Endoscopy ; Female ; Humans ; Male ; Middle Aged ; Recurrence ; Retrospective Studies ; Sinusitis ; therapy ; Treatment Outcome ; Young Adult

OBJECTIVETo investigate and arrange the ethno-pharmacological information of Schisandraceae plants in China.

METHODThe information was obtained by literature search, specimen inspection, field resource investigation and samples collection.

RESULTTwenty-six Schisandraece plants (inlcuding 4 varieties) have been used as folk medicines in different regions of China, the identical medicinal parts of different species in one genus show the similar usage, action and indications, and different medicinal parts with different administrated ways show different action and indications.

CONCLUSIONThe results provide reliable information for resource development and comprehensive utilization of Schisandraece plant resource in China.

China ; Drugs, Chinese Herbal ; pharmacology ; Ethnopharmacology ; Schisandraceae

OBJECTIVE: To report the experience with canalplasty during the operation of overlay tympanoplasty. METHOD: A retrospective review was performed on 56 patients (59 ears) that underwent tympanoplasty and canalplasty (part with intact canal wall mastoidectomy). Transcanal and postauricular incisions were made, and the posterior canal skin flap was elevated and fixed with retractor, while the anterior flap was freed. A drill was used to remove the anterior and inferior bone bulges and the adjacent bone to expose the tympanic sulcus and annulus adequately, and the epithelium of tympanic membrane remnant was removed thoroughly. After the eradication of the middle ear disease, temporal fascia was used as an overlay graft and the canal skin was replaced, and the gel-foam soaked in antibiotic and Dexamethasone solution was used to compress the canal. The patients began to use ear drops 1 week after surgery, and the gelfoam in canal lasted for 4-6 weeks. RESULT: Follow-up was conducted for 0.5-3.5 years respectively, all patients gained stage I incision cure, the external auditory canal was wide and tympanic membrane gained a good shape, the complications of skin flap necrosis, external canal stenosis and cholesteatoma pearl were not occurred. CONCLUSION Canalplasty was the necessary procedure in the operation of overlay tympanoplasty which could conduce to de-epithelization of the membrane, placement of fascia and prevention of the occurrence of cholesteatoma pearl.
Adolescent ; Adult ; Aged ; Child ; Cholesteatoma, Middle Ear ; surgery ; Ear Canal ; surgery ; Ear, External ; surgery ; Ear, Middle ; surgery ; Fascia ; transplantation ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Surgical Flaps ; Treatment Outcome ; Tympanoplasty ; methods ; Young Adult

OBJECTIVETo study the chemical constituents in the fruits of Schisandra sphenanthera.

METHODThe constituents were isolated by their silica gel column, Sephadex LH-20 gel column, and their structures were elucidated by their chemical properties and spectroscopic analyses.

RESULTTwelve compounds were isolated and identified as (+)-anwulignan (1), deoxyschizandrin (2), interiotherin A (3), schisantherin A (4), beta-sitosterol (5), schisantherin D (6), 4-hydroxybenzaldehyde (7), 6-O-benzoylgomisin O (8), schizandronic acid (9), schisanlactone D (10), schisanlactone B (11), kadsulactone A (12).

CONCLUSIONCompounds 3, 7, 10-12 were obtained from this plant for the first time.

Alkanes ; chemistry ; Drugs, Chinese Herbal ; chemistry ; Fruit ; chemistry ; Organic Chemicals ; analysis ; chemistry ; isolation & purification ; Schisandra ; chemistry

OBJECTIVE To compare the influence of age on the recovery of sudden sensorineural hearing loss.METHODS Detailed medical data of patients were reviewed.The patients were diagnosed as sudden sensorineural hearing loss from Jan 2010 to June 2018 and accepted treatments with neurotrophic drugs,steroid or hyperbaric oxygen.Age grouping was performed by every 5 years'interval.The treatment efficacy and hearing improvement were compared according to the age.RESULTS There were one hundred and sixty-three patients in this study.The majority of patients had moderate or above hearing loss,and most of the hearing curve was flat and profound type.The overall recovery rate was 56.44%,hearing gain was averaged 21.88 dB.55-60 years group had largest number of patients in the 11 age groups.Even with different treatment,the patients aged 57-66 years had the bad recovery,including the hearing gain data and total effective rate.CONCLUSION Ages has influence on the recovery of sudden sensorineural hearing loss,it maybe correlated with the etiology and patients'condition.