AIM. To present a case of Horner's syndrome which developped after neck surgery.METHODS: The patient was admitted to our clinic with the complaint of droop of right eye's upper lid which appeared after having a neck surgery for cervical radiculopathy. Full ophthalmologic examination was done, including pharmachological tests to confirm the diagnosis.RESULTS: The right upper eyelid was 1.5mm ptotic.Right pupil was miotic. There was a lag of dilation in the right pupil in the dark. Facial anhidrosis was present at the right side of the face. Right pupil dilated and upper eyelid ptosis improved with apraclonidine 5g/L application.CONCLUSION: Sympathetic denervation of the eye (Homer's syndrome (HS)) usually presents as a triad of ptosis of upper eyelid, miosis and facial anhydrosis. We present a case of HS after anterior cervical discectomy operation which is an unusual and rare cause of persistant HS.