Introduction: Last Decades, Date by date medical developments providing friendly, high-efficiency treatment equipment and services in developed countries are working toward an advanced, as our country medical services are trying to that country’s technology has been introduced. In our country every day there is only surgical care necessary to endocrine gland disorders, including most common thyroid surgery. It is open and robotic assistant endoscopic surgery in the world. But robotic assistant endoscopic surgery is too expensive and impossible in our country. Thus we chose Thunderbeat for open thyroid surgery in especially huge enlarged goiter and vascularized goiter to try prevent bleeding, recurrent laryngeal nerve palsy and post operation hematoma and other complications Thunderbeat is new generation instrument combines an advanced bipolar clamp to the existing ultrasonic cutter. Materials and Methods: M 51-years-oldwoman was admitted to Mongol Hyundae hospital because of front of neck pain, multi nodular goiter, tachycardia, sweaty and not controlling emotion. Anamnesis: She diagnosed to Thyrotoxicosis in 2005 and she took medicine last ten years but not controlling that poisoning. Status locals: Huge enlarged goiter in front of her neck Treatment plan: 1. Preoperative Preparation 2. Operation: Open total thyroidectomy 3. Medicine 4. Wound dressing 5. Observation We did operation after day of admission day, Patient is placed in a Semi erect position with a folded sheet underneath the shoulders so that the head is sharply angulated backward on the multifunctional surgical table under general anesthesia. We used thunderbeat from muscular to all procedures, dissection both thyroid gland and isthmus after Kocher skin incision and sub skin tissue dissected. There is no complication while procedure and post operation days Result: Nodular hyperplasia of thyroid gland with focci of micro adenomatous change Conclusion: Thunderbeat in use open thyroid surgery first outcomes blood loss than 30ml, no injury of recurrent laryngeal nerve and no penetration ligament of Berry while procedure, second outcomes no hematoma, painless, wound healing process faster and short time hospitalization.

Introduction: Last Decades, Date by datemedical developments providing friendly,high-efficiency treatment equipment andservices in developed countries are workingtoward an advanced, as our country medicalservices are trying to that country’s technologyhas been introduced. In our country everyday there is only surgical care necessary toendocrine gland disorders, including mostcommon thyroid surgery. It is open androbotic assistant endoscopic surgery in theworld. But robotic assistant endoscopicsurgery is too expensive and impossible inour country. Thus we chose Thunderbeatfor open thyroid surgery in especially hugeenlarged goiter and vascularized goiter to tryprevent bleeding, recurrent laryngeal nervepalsy and post operation hematoma andother complicationsThunderbeat is new generation instrumentcombines an advanced bipolar clamp to theexisting ultrasonic cutter.Materials and Methods: M 51-years-oldwomanwas admitted to Mongol Hyundaehospital because of front of neck pain, multinodular goiter, tachycardia, sweaty and notcontrolling emotion.Anamnesis: She diagnosed toThyrotoxicosis in 2005 and she tookmedicine last ten years but not controllingthat poisoning. Status locals: Huge enlargedgoiter in front of her neckTreatment plan:1. Preoperative Preparation2. Operation: Open total thyroidectomy3. Medicine4. Wound dressing5. ObservationWe did operation after day of admissionday, Patient is placed in a Semi erect positionwith a folded sheet underneath the shouldersso that the head is sharply angulated backwardon the multifunctional surgical table undergeneral anesthesia. We used thunderbeatfrom muscular to all procedures, dissectionboth thyroid gland and isthmus after Kocherskin incision and sub skin tissue dissected.There is no complication while procedureand post operation daysResult: Nodular hyperplasia of thyroidgland with focci of micro adenomatouschangeConclusion: Thunderbeat in use openthyroid surgery first outcomes blood lossthan 30ml, no injury of recurrent laryngealnerve and no penetration ligament of Berrywhile procedure, second outcomes nohematoma, painless, wound healing processfaster and short time hospitalization.

Background: Globally, researchers have found that while the use of synthetic drugs worldwide has increased by 2.1 2.5%, the use of natural medicines has grown by 3.5-4.8%. In modern times, the pharmaceutical industry has become more advanced, and the use of plant-based medicines is increasing. As a result, there is a growing need to identify biologically active compounds in medicinal plants and produce domestic pharmaceutical products to replace imported medicines. Due to the limited research on evaluating the quality of the raw materials of the Asian globeflower(Тrollius asiaticus L.) this study serves as a basis for assessing the quality of that flowers Aim: Determining the quality parameters of flower of Trollius asiaticus L. Materials and Methods: The research work was carried out with the support of the “Quality Control Laboratory for Medicine” of the School of Pharmacy, MNUMS. The quality assessment of flower of Trollius asiaticus L. was conducted according to established parameters outlined in the National Pharmacopoeia of Mongolia and Russian pharmacopeia and Chinese pharmacopeia methods. Parameters such as appearance, and microbiological purity were evaluated. Statistical analysis of research data was performed using Microsoft Excel and SPSS 25 software to calculate the mean, standard deviation, and percentage. Results: The flower of Trollius asiaticus L. is orange red or orange, plant does not contain organic and mineral impurities, the quality analysis of flavonoid compounds by the thin layer chromatography, a spot with RF=0.5125 was detected at the same level as orientin as a standard substance, and a spot with RF=0.875 was detected at the same level as gallic acid as a standard substance when analyzing the quality of polyphenolic compounds, moisture contain is 5.52%, sulfated ash contain is 9.12%, acid insoluble ash contain is 3.39%, water soluble extract contained 36.21%, the total polyphenolic compound contained 5.37±0.22%, total flavonoid compound contained 0.0399±0.013%. Conclusion The quality parameters of flower of Trollius asiaticus L. have been determined by the Mongolia National of Pharmacopoeia, the Pharmacopoeia of Russian and China.

Purpose:To identify theeffect of Antacid calcium-preparation on gastroeosophageal reflux disease by using pH meterfor 24 hour monitoring analysis. Study methodology:A randomly controlled test was used for the study. Study objects were administered Antacid calcium-6 preparation and their gastric acidity level was identified by pH monitoring analysis for 24 hours. Theimpact of preparation in regards with before and after treatment and their relationship were analysed by t-test. Results:The 24-hour pH meter analysis of Antacid calcium-6 preparation indicated that before administration of preparation the gastroeosophageal pH=5,75±0,14, which has increased after the administration to pH=9,7±0,02 and the average duration was 7,8±0,09 days. In other words, the alkalinizing effect was statistically significant (p<0.001). Also, According to the criteria developed by the DeMeester, the daily prevalence of reflux, the prevalence of reflux that continued for more than five minutes and the DeMeester index indicated that the preparation was significantly efficient (p=0.041). The neutrialising effect of the preparation was established by using the criteria method developed by G.A. Agafonova and A.P. Kholopov (1984), and after administering the preparation, the gastric level was pH=4,6±1,5 indicating that the preparation had a neutralising effect. The average duration for neutralization was 19,3±0,9 hours. Conclusion: Аntacid calcium-6 preparation was effective in neutralising the gastric acidity and it was appropriate for treatment of GERD, chronic gastritis.

The study’s goal was to determine efficiency of the Antacide Calcium-6 to Gastroeosophageal reflux disease (GERD) by radiological study. The material and methods are experimental study and we collected occasionally participants. The study was 2 stages. In the first stage, participants are given Antacide Calcium-6 p.o, and then monitored gastric acidity by pH monitoring for 24 hours. We evaluated how to effect to reflux condition in before and after treatment by relational groups t score. Also we determinate efficient to GERD by DeMeester score, G.A. Agafanova, A.P.Kholopov scores, time to neutralize gastric acidity by time to gastric acidity return normal. First stages results are this preparation alkalified eosophagus (р<0,001). The second stage: Participants are given Antacide calcium-6 for 21 days p.o (1 times per day, in 10 A.M, 1.5g) after collected GerdQ questions and did gastroeosophageal flexible endoscopy. Treatments results evaluated by GerdQ and Antacide calcium-6 decreased to gastro- eosophageal reflux by 72.1% (р<0,001). Eosophageal mucous membrande changes were 86.11% (n=31), gastric inflammation’s actitity was decreased 72.22% (n=26) by endoscopic examination. In conclusion, Antacid calcium-6 biological preparation has neutralizing actions to gastric acidity. Therefore this preparation is comfortable to treat GERD and chronic gastritis.