1.Assessment of renal function in chronic hepatitis C patients
Gantogtokh D ; Batsukh B ; Batbold B ; Burmaajav B
Mongolian Medical Sciences 2023;204(2):3-13
Background:
The association between hepatitis C virus (HCV) infection and chronic kidney disease (CKD) still
remains controversial. We aimed to investigate whether HCV really affects renal function, and to
analyze the association between clinical effects of CHC and decreased kidney function (assessed by
glomerular filtration rate (eGFR) level).
Aim:
Study of renal dysfunction in chronic hepatitis C virus infection
Materials and Methods:
An estimated 222 patients with HCV infection and 222 age- and sex-matched community-based
control individuals without HCV were enrolled (1:1, case and control ratio) in this study between from
June 2022 to March 2023. We used the modification of diet in renal diseases to calculate eGFR.
This study was approved by the review board of the Ethics Subcommittee of Ach Medical University
and followed the Declaration of Helsinki. All statistical analysis was performed with SPSS version
26.0 software (SPSS Inc., Chicago, IL, USA), and a P value < 0.05 was considered statistically
significant. Continuous variebles were presented as mean ± standard deviation, while categorical
data was represented as numbers and percentages. Independent t-tests were used to compare the
differences in parametric variables. The Mann-Whitney U test was performed to compare the follow-up
period. Pearson’s chi-squared and Fisher’s exact tests were used to compare categorical variables.
Multivariate logistic regression was used to identify the risk factors associated with recurrence.
Results:
The median age of the respondents was 40 (range 21-70). In the case group, the speed of hanging
judgment was 105.3±24.5, and in the control group, it was 118.7±18.5, which was a statistically
significant difference (p<0.05, p<0.05). It was observed that the rate of filtration of the renal is below
90 or the loss of renal function increases with age (47.50±9.3 vs 40.21±11.1; p<0.01). In order to
reduce the effect of age, when evaluating the renal function of participants over 45 years of age
in the case-control group, the HCV was 99.69 in the case group and 111.05 in the control group,
although there was an age effect on the decline in HCV in both groups, but it decreased more in the
HCV-infected group. When comparing two groups (<3.25, >3.25) with liver fibrosis degree above
and below 3.25, the higher degree of fibrosis affects the decrease in the rate of hepatic filtration (112.92±19.8 vs 105.23±27.1; p<0.01). The proportion of cryoglobulinemia was high when renal
dysfunction was beginning or when the GFR was below 90 (<90). Logistic regression analysis showed
that cryoglobulinemia had the greatest influence on the decrease in glomerular filtration rate (OR
4.22, 95% CI 1.97-9.00, p<0.05). The relationship between age and the decline in hanging judgment
speed was statistically significant and directly moderate (r=0.95, p=0.009). On the other hand, there
is a statistical relationship between gender and the decrease in the speed of hanging judgment, with
a probable and weak correlation (r=0.07, p=0.01).
Conclusion
Our study found that the patients with HCV infection are associated with a low
eGFR compared with non-HCV–infected patients. This association is consistent in age, gender,
cryoglobulinemia and liver fibrosis patients.
2.STUDY ON CHILDREN WITH CLEFTS, VISITED SPEECH THERAPY SESSIONS BETWEEN 2007-2012
Delgerbaigal M ; Bulgan B ; Ayanga G ; Batsukh Sh ; Bat-Erdene M ; Otgonbayar B ; Ariuntuul G
Innovation 2018;12(4):33-39
BACKGROUND. Congenital Cleft Lip and/or Palate (CL/P) is a common craniofacial birth defect and occurs 1 per 500-700 live births in average. Children with CL/P at a higher risk for speech/language problems due to the anatomical and structural differences in the oral and nasal cavities, Velopharyngeal Insufficiency causing speech disorders with articulation, phonation, and resonance, respectively. It leads to long-lasting adverse outcomes, influencing quality of life and causes obstacles in child’s socialization. Speech in 2007 Therapy team of School of Dentistry ( G. Ariuntuul , B. Bulgan, U. Azzaya, B. Batsukh, M. Bat-Erdene), Mongolian National University of Medical Sciences (MNUMS) (former Health Sciences University of Mongolia) established and successfully conducted a first clinical speech therapy sessions for children with clefts in Mongolia based on the Department of Oral and Maxillofacial Surgery (G. Ayanga et al.) of National Maternal and Children’s Health Center (NMCHC). Since 2012 the speech therapy team of School of Dentistry, officially transferred the equipped operating speech room to NMCHC and speech pathologist B. Bulgan, supervised and trained by Ariuntuul G. recruited by NMCHC for a full time position and working as a member of multidisciplinary team till present.
OBJECTIVES. To assess and analyze registry data of children with clefts, visited speech therapy sessions of speech pathology team of School of Dentistry, MNUMS during 2007 through 2012.
MATERIAL AND METHODS. Registry based retrospective study was conducted to obtain demographic and speech disorder related data of children with clefts, visited speech therapy sessions between 2012-2017 at the NMCHC.
RESULTS. In total 203 participants are attended the speech therapy sessions: 103 male (51%), 100 female (49%). Out of total 203 children 144 (71%) had Cleft Lip and Palate (CLP), 44 had cleft palate only (22%), 15 had cleft lip (7%), respectively. Average age for primary cleft surgery was 1y13m, where as for secondary was 4y22m.
CONCLUSION. For speech therapy session for children with clefts boys were dominant compared to girls (1:1.03). By the types of clefts children diagnosed with Cleft Lip and Palate was prevalent to attend treatment classes. There is a need in early CL/P diagnosis, using birth screening and furthermore, traning of speech therapists/pathologists are important for development of multidisciplinary team, surgery outcome and improvement of quality of life of children with clefts.
3.Fibular fixation in tibiofibular fractureses
Uranbileg B ; Badamgarav G ; Otgonsaikhan N ; Baasansuren Sh ; Erdenebileg A ; Batsukh O ; Naranbat L ; Sanchin U
Innovation 2020;14(2):72-76
Background:
Treatment of adult tibiofibular fractures, especially severely comminuted
fractures, is technically challenging due to the lack of reduction markers and difficulty in restoring
the alignment. Fixation of the fibula can facilitate reduction of the tibia fracture and restoration
of the lower extremity alignment.
Methods:
Between 2018-2019 we have operated on 50 patients who have lie on the same
plane of tibiafibular fractures. Measures of angulation were obtained from radiographs taken
immediately after the surgery, a second time 3 months later, and at 3-month follow-up. The
analysis was performed with STATA.
Results:
Fixating fractures of tibia and fibula at same level were not shown to have complications
on the development of nonunion including fibular shortening, hindfoot alignment, slow process of
nonunion and unstableness.
Conclusions
We recommend fibular fixation in all 50 distal fractures when both fractures lie on
the same plane and the tibial fracture is relatively stabilized.
4.Open broström-gould repair vs arthroscopic anatomical repair of the anterior talofibular ligament for chronic lateral ankle instability
Amgalankhuu O ; Shiirevnyamba A ; Batsukh S ; Erdenebold B ; Zoljargal S ; Naranbat L ; Munkhsaikhan T
Mongolian Journal of Health Sciences 2025;88(4):221-225
Background:
During inversion injuries of the ankle joint, the anterior talofibular ligament (ATFL) is the most commonly
injured structure. Injuries to the lateral collateral ligaments of the ankle, either in isolation or in combination with injury
to the calcaneofibular ligament (CFL), account for approximately 60-65% of all ankle ligament injuries. In recent years,
several studies have examined the impact of lateral ankle ligament injuries on lifestyle and overall health. Repeated inversion injuries-particularly those occurring three or more times-can lead to chronic ankle instability (CAI). In the treatment
of ankle instability, both open and arthroscopic surgical techniques are widely used internationally. In Mongolia, there is
an increasing clinical need to evaluate and compare the outcomes of arthroscopic versus open surgical repair of lateral
ankle ligament injuries. This need forms the basis of the current study.
Aim:
The comparative studies on open vs arthroscopic anterior talofibular ligament (ATFL) repair are limited. This study
aimed to compare the early therapeutic efficacy and cost between the traditional open Broström-Gould repair and all-arthroscopic anatomical repair of the ATFL for chronic lateral ankle instability.
Materials and Methods:
A total of 40 patients with chronic lateral ankle instability undergoing repair of the ATFL be
tween September 2024 and February 2025 were retrospectively included with a traditional open surgery (n=10) group
and an arthroscopy (n=17) group. The surgery duration, surgical cost, postoperative complications, and the preoperative/postoperative American Orthopaedic Foot & Ankle Society Score (AOFAS) and Karlsson-Peterson score were compared
between groups.
Results:
Compared to the anatomical group, the non-anatomical group had significantly shorter surgery and hospitalization durations. Three months after the operation, the AOFAS and Karlsson scores significantly improved in both groups.
Nevertheless, there was no significant difference in the AOFAS and Karlsson scores between groups at both preoperative
and postoperative assessments. No significant difference was found in the incidence of postoperative complications between the two groups.
Conclusion
1. These results suggest that open Broström-Gould repair and all-arthroscopic anatomical repair of the ATFL have
comparable therapeutic efficacy for chronic lateral ankle instability.
2. The arthroscopic surgery had a smaller incision, while the open Broström-Gould had a shorter surgery duration and
lower cost.