1.STUDY OF SERUM LIPID PEROXIDE IN CHILDREN WITH PNEUMONIA
Kejun NAN ; Baoyu LU ; Shuner HONG
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(02):-
In order to lind the change of serum lipid peroxide (LPO) we examined 41 children with pncumonia. The results showed that LPO was obviously higher in acute stage than in convalescence.(P
2.Recent research progress on swainsonine
Haiyun QUAN ; Zhenhui REN ; Hao LU ; Shuai WANG ; Ruixu XUE ; Jianguo WANG ; Chenchen WU ; Baoyu ZHAO
Chinese Journal of Veterinary Science 2017;37(8):1633-1640
Locoweeds are presently defined as those species of the genera Oxytropis and Astragalus (family Leguminosae) that specifically contain the key toxic constituent,swainsonine.After ingesting locoweeds,livestock can develop poisoning disease characterized by chronic dysfunction of the nervous system,which causes severe economic losses to the pastoral areas.In addition,swainsonine has attracted a great attention from toxicology and medicine fields,due to its dual role of toxicity and pharmacological activity.This review not only summarizes the latest research progress of toxicity and its poisoning mechanism,pharmacological activity,source,and biosynthesis pathway of swainsonine,but also speculates the possible regulatory enzymes involved in the synthesis pathway.Moreover,the future research on swainsonine is also looked ahead,which provide references for the prevention and treatment of locoism.
3.Effects of madder on bone biomechanical property in rats.
Chenchen WU ; Xiaowen YANG ; Wenlong WANG ; Shanshan WANG ; Dandan CAO ; Feng MA ; Jianguo WANG ; Hao LU ; Baoyu ZHAO
Journal of Biomedical Engineering 2015;32(1):110-115
Bones are stained into red color with feeding madder, but we do not know whether the fed madder can change the bone biomechanical properties and bone mineral contents in animals. In this research, we established a rat model with feeding madder. The bone biomechanical properties were detected by universal material mechanics, bone mineral contents were detected by inductively coupled plasma mass spectrometry and spectrometer, and red color material in bone was analyzed by high performance liquid chromatography. The results showed that bone biomechanical parameters in femur diaphysis in the 10% and 15% group rats were significantly higher than those in the control group after feeding madder for 6 months. The level of calcium, magnesium and zinc in femur diaphysis in 10% and 15% group rats were higher than those in the control group after feeding madder for 6 months. However, it was shown that the kidney congestion and hyperemia and the level of blood urea nitrogen and creatinine in the 15% group rats were significantly different compared to those in the control group rats after feeding madder for 6 months. The red colored material in bone is related to alizarin analyzed with high-performance liquid chromatography. The conclusion could be drawn that feeding 10% madder in diet was not toxic to the rats fed for 6 months, and it could improve bone biomechanical properties and increase bone mineral elements.
Animals
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Anthraquinones
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toxicity
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Biomechanical Phenomena
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Bone Density
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Bone and Bones
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drug effects
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physiology
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Calcium
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Femur
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Magnesium
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Rats
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Zinc
4.Repair of open compound lower extremity wounds
Jingmin ZHU ; Tianzhi HAO ; Gang LU ; Zhi ZHOU ; Zhifu SUI ; Jingjie LIU ; Xiaojun TU ; Jinchao LUO ; Baoyu FAN ; Chuangong CHEN ; Yalin ZHONG
Chinese Journal of Trauma 2008;24(6):415-418
Objective To explore the repair of the open compound wounds in lower extremities caused by multiple factors. Methotis Transplantation of cutaneous.musculo-cutaneous or greater omentum flaps were applied to 155 patients of open compound lower extremity wounds. Results The wound healing rate following first operation was 50% and that following two operations was 14.8%.While the wounds were healed in 7.7% of patients after three operations. Conclusion Transplantations of cutaneous,musculo-cutaneous or greater omentum flaps ale effective to repair and reconstruct the open compound lower extremity wounds.
5.Practice and exploration of high-quality development of residential training bases
Baoyu WANG ; Gang CHEN ; Mengyi ZHOU ; Honghong WU ; Suxiu CHEN ; Zhongqiu LU
Chinese Journal of Hospital Administration 2022;38(8):627-630
In order to promote the connotation construction of the resident standardized training bases and improve the training quality, a tertiary hospital made key breakthroughs against the existing problems in the base under the guidance of national key training base standards in September 2020. Optimization and innovation were explored in terms of residential teaching supervision, performance appraisal system, regular teaching meeting, educational fund management, pilot project of full-time residential teaching secretaries, clinical skill center construction, cultivation of faculty development, and so on. These experiments have paved the way to high quality and sustainable development of residents standardized training. By the end of December 2021, the hospital had achieved significant progress in such aspects as residential teaching atmosphere, resident learning initiative, and training base branding. These achievements improved the quality of resident standardized training of the hospital in general, and provided a reference for promoting the high-quality development of residential training in China.