This paper reported activation of mice peritoneal macrophages by Sheng Ji Ointment (a Chinese traditional ointment for external application) were markedly inhibited from migrating out of capillary tubes by Sheng Ji Ointment. The source of Elephantine hide(象皮)is in short supply. Whether we Can use Cattlehide (牛皮)instead of the Elephatine hide for the Sheng Ji Ointment,the migrating inhibited effects of both are similar. The experimental results may throw some light on their clinical application.