1.TLC-scanning Determination of Astragaloside Ⅳ
Jing LU ; Baoqin WANG ;
Chinese Traditional Patent Medicine 1992;0(06):-
Astragaloside Ⅳ content in species of Radix Astragali seu Hedysari of Chinese materia mediea has been determined with dual wavelength,reflect zig-zag scanning,external-standard dual-point methods. The average recovery and coefficient of variation(CV)are 99.15% and 3.71%(n=6),respective- ly.
2.HPLC Determination of Schizandrin A and B in Gengnianan and Fructus Schisandrae
Chinese Traditional Patent Medicine 1992;0(09):-
The content of schizandrin, A and B in Fructus Schisandrae and its preparation——Gengnianan has been determined by HPLC on YWG C_(18) column. Mobile phase consists of acetonitrile and water (70:50). Detection is at 254nm with the UV detector.
3.TLC-scanning Determination of Geniposide in Compound Zhizi Granules(Gardenia Jasminoides Ellis, Radix Scutellariae, etc.)
Chinese Traditional Patent Medicine 1992;0(01):-
The content of geniposide in Compound Zhizi Granules was determined With TLC-scanner. The optimum experiment design obtained with orthogonal test could eliminate the disturbance of other components. The result was satisfactory.
4.Early identification and intervention of cerebral palsy
Lei WANG ; Chunmei YAO ; Baoqin GAO
Chinese Journal of Applied Clinical Pediatrics 2016;31(14):1116-1118
Cerebral palsy (CP) describes a group of disorders of the development of movement and posture,causing activity limitation attributed to disturbances,which occurred in the fetal or infant brain.Early identification and intervention of CP has always been a difficult topic in the research of neuroscience.The intervention should be focused on infants showing early signs of CP.Such signs may be efficiently detected by a combination of neuroimaging and the General Movements Assessment.Besides movements,enriched environments,active participation,parental coaching have benefits to early intervention.In this investigation,the early identification and intervention in cerebral palsy were focused.
5.Vocational Safety Protection for Clinical Nurses
Baoqin CHEN ; Jianguo FU ; Xiaoyan WANG
Chinese Journal of Nosocomiology 2009;0(17):-
OBJECTIVE To investigate the vocational safety protection in nurses in the clinic work,then to enhance the protection consciousness of nurse,and the usage of protection.METHODS The relative questions on the vocational protection were investigated in the nurses from one tiatiary care level hospital in China by the Questionnaire designed by ourselves.RESULTS Among the one hundred and fifty nurses investigated,one hundred and one(67.5%)of them just knew little about the vocational exposure,and one hundred and four thought they just accepted little education of vocational exposure.The average score of the usage of protection appliance was 54.89?14.70.The average score was increasing with the higher degree of the study and with the length of service.CONCLUSIONS The vocational safety protection should be emphasized,the protection appliance should be provided comprehensively,and clinic protection system of full efficiency with long time and ensuring system should be founded.
6.Studies on the Quality standard of Multicomponent Dibiling
Shujie ZHAO ; Lingling LI ; Baoqin WANG
Chinese Traditional and Herbal Drugs 1994;0(10):-
The Quality Standard of Multicomponent Dibiling, a nose drop for nasitis was studied.The presence of garlic, cassia and ephedra were demonstrated by TLC and the amouns of Allicin in the preparation was determined by HPLC. The method is simple, rapid and accurate.Average recoyery (n = 6 ) was 101.41 %and CV%was1 .76.
7.Preparation and properties of carboxymethyl chitosan calcium
Wendi CAI ; Jinxin CHU ; Baoqin HAN ; Changhong WANG ; Wanshun LIU
Chinese Journal of Tissue Engineering Research 2010;14(3):567-570
BACKGROUND: Carboxymethyl chitosan is a water-soluble derivate modified from chitosan, with various biological activities. It is a good ligand of metal ion and can integrate Ca~(2+) to prepare a novel biological material. OBJECTIVE: To explore a method for preparing carboxymethyl chitosan calcium (CCC) and analyze its properties and structure. METHODS: CCC was produced by carboxymethyl ohitosan reacting with solution of calcium chloride. The solubility, carboxymethylation degree, rotational viscosity, and calcium content of CCC were determined, and infrared and ultraviolet spectral analyses were performed.RESULTS AND CONCLUSION: The calcium content of CCC was approximately 15%. Compared with carboxymethyl chitosan, infrared spectrum and ultraviolet spectrum of CCC were changed. The prepared CCC is a new calcium compound through property and structural analysis.
8.Neuroprotective effect of cerebrolysin in ophthalmology
Mingqian ZHAO ; Yongyao MAI ; Baoqin LIN ; Xueting LUO ; Ting WANG
Chinese Journal of Biochemical Pharmaceutics 2016;36(12):196-199
Cerebrolysin is an aqueous mixture of amino acids extracted from porcine brain.Cerebrolysin, contains a variety of amino acids and low molecular weight peptides, are permeable to the blood-brain barrier and blood-ocular barrier and can directly act on neurons in the CNS.As amino acid-based neuroprotective reagents, cerebrolysin can improve the neuronal metabolism, promote synapse formation and induce neuronal differentiation, and thus elicit neuroprotective efffectagainst insults such as ischemia , neurotoxins and so on.Cerebrolysin is clinicly used to treat eye diseases such as traumatic eye damage, glaucoma, optic atrophy ect.This paper systematically summarizes the studies on preclinical and clinical application of cerebrolysin in ophthalmology.
9.Study on lead expelling effect of carboxymethyl chitosan calcium in lead poisoned mice
Jinxin CHU ; Baoqin HAN ; Wendi CAI ; Changhong WANG ; Wanshun LIU
Chinese Journal of Marine Drugs 1994;0(01):-
Objective To observe the effect of carboxymethyl chitosan calcium(CCC) on the concentration of lead,calcium,and liver antioxidative capacity in lead poisoned mice.Methods mice were randomly divided into 6 groups.Three test groups were treated with CCC at three doses.The lead poisoned mice model was established by giving water containing lead acetate,and then CCC was administered to mice once a day.After 30 days,the mice were killed and the content of lead in blood,liver,brain and femur were determined by atomic absorption spectrophotometer,and antioxidative capacity in liver was measured using assay kit.Results CCC could reduce the contents of lead in blood,brain,liver and femur significantly,decrease the level of maleicdialdehyde(MDA),increase activities of superoxide dismutase(SOD),glutathione peroxidase(GSH-Px)and total antioxidative capacity(T-AOC) in liver markedly. Conclusion CCC can promote the excretion of lead,increase the content of calcium in femur and antioxidative capacity in lead poisened mice.
10.Screening of alginate producing strain and optimization of fermentation condition
Min PANG ; Changhong WANG ; Baoqin HAN ; Wanshun LIU
Chinese Journal of Marine Drugs 1994;0(03):-
Objective A strain with high alginase activity was screened and isolated by decomposing sodium alginate from the decaying parts of brown alga Laminaria japonica and Undaria pinnatifida,in order to produce alginase.Methods The strain s4 with high alginase activity was chosen by filtration.The alginase producing media was optimized and the alginase was produced and its characterization was investigated.Results The optimum fermentation conditions for alginate lyase producing as follows: media AlgNa 1.2%,NH4Cl 0.9%,NaCl 1.5%,pH=7.5,and temperature 25℃.Conclusion The alginase produced by strain s4 showed high alginase activity and good stability.