1.Chinical effects of three kinds of active IUD inserted immediately after induced abortion
Chinese Journal of Primary Medicine and Pharmacy 2012;(24):3697-3698
Objective To compare the effects of three types intrauterine device(IUD)insertion immediately after vacuum aspiration.Methods 120 cases of artificial abortion immediately placed IUD women were selected.According to the IUD type,the patients were divided into the TCu3s0AIUD group 40 cases,active gamma type 40 cases in group IUD,palace copper 40 cases in ZooIUD group,followed up for 12 months.Results All of the subjects were not with IUD pregnancy.The termiration rate was Palace copper ZooIUD group 27.5%,active gamma type IUD group7.5% TCu3s0AIUD 15.0%,three groups of termination rate had a significant difference(F=5.88,P<0.05);threegroup IUD complications had no statistical difference(all P>0.05).Follow-up for 12 months,palace copper group ZooIUD menstruation increase incidence rate of 42.5%,significantly higher than the other two groups 15.0%,20.0%(F=8.96,P<0.05);the difference between the three groups in irregular bleeding was significant(F=17.77,P<0.01).Conclusion The three kinds of IUD has good contraception effect,wherein the active gamma IUD has smaller adverse reaction,continue to use rate is high,so it is worthy of clinical application.
2.The clinical effect and safety of the combination treatment of lamivudine and adefovir dipivoxil in decompeusated hepatitis B cirrhosis
Lefeng DONG ; Baokun BU ; Yanfeng YIN
Chinese Journal of Postgraduates of Medicine 2011;34(19):27-29
Objective To study the clinical effect and complication of the combination treatment of lamivudine and adeforvir dipivoxil in decompeasated hepatitis B cirrhosis. Methods Eighty-six cases of decompensated hepatitis B cirrhosis were divided into the observation group and the control group with 43 eases each by random digits table. The control group was treated with routine treatment and lamivudine, and the observation group was added with adefovir dipivoxil on the base of the treatment in the control group. The clinical effect after 12 months' treatment was evaluated. Results After 12 months'treatment, the level of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBil), albumin ( ALB ) and Child-Pugh grade had significant improvement than that before the treatment in two groups(P < 0.05 ), and in the observation group they improved more obvious (P <0.05). The frequence of seroconversion of HBeAg/HBeAb and HBV DNA in the observation group was higher than that in the control group [86.05%(37/43) vs. 65.12%(28/43),79.07% (34/43) vs. 55.81%(24/43)], and the difference between the two groups was significant (P < 0.05 ). Seven cases of times complications happened in the control group and 8 cases of times complications happened in the observation group and the difference between the two groups was not significant (P > 0.05 ). Conclusion The effect of lamivudine and adefovir dipivoxil in the treatment of decompensated hepatitis B cirrhosis is superior to the only lamivudine.