1.The Value of MRI in the Diagnosis of Subarachnoid Hemorrhage
Suijie LIU ; Yuechun LI ; Baojun WANG
International Journal of Cerebrovascular Diseases 2008;16(5):336-341
According to the traditional point of view,CT and lumabar puncture are the main means in the diagnosis of subarachnoid hemorrhage(SAH).The values of conventional MRI T1-weighted imaging(T1WI)and T2 weighted imaging(T2WI)are very little in the diagnosis of SAH.With the development of MRI technique and the research and application of novel MRI sequences,the value of MRI are gradually recognized and affirmed in the diagnosis of SAH.and has shown its superiority.MRI isn't inferior to CT in the diagnosis of acute SAH.evidently superior to CT in the diagnosis of subacute,chronic and atypical SAHs and superior to CT in the diagnosis of the complications of SAH.MRI is valuable in screening for intraeranial aneurysms and postoperative follow-up.
2.Application of proximal femoral nail in the treatment of femoral intertr ochanteric fracture
Zongren WANG ; Changgui LIU ; Baojun WANG
Chinese Journal of Orthopaedic Trauma 2002;0(03):-
Objective To evaluate the clinical effects in t he treatment of femoral peritrochan teric frac-tures by PFN(proximal femoral nail).Methods A retrospective analysis was done in the treatment of femoral peritrochanteric fractures(72cases).38cases were male and 44cases female.Their age ranged 64~96years old with the average age being 78years old.70cases were intertrochanteric f ractures(EvensⅠtype 16,Ⅱtype 31,ⅢA type 14,ⅢB type 6,Ⅳtype 3),and 2cases subtrochanteric fractu res.Results65patients were followed up for over 6months.All fractures healed and all patients could take care of themselves and were satisfied with t he clinical curative effect except one patient who had the lag screw pulled o ut and coxa vara because of serious os-teoporosis.Conclusion PFNis a better way to cure femoral peritrochanteric fractures because of few complications and simple surgical procedure.Bein g a micro-trauma technique,it is worthy of wide application in clinic.[
3.The Expression of c-erbB-1 and c-erbB-2 Oncoproteins in Basal Cell Carcinoma and Squamous Cell Carcinoma of Skin
Baojun LIU ; Haitao ZHANG ; Suqin LI
Chinese Journal of Dermatology 1995;0(04):-
The expression of c-erbB-1 and c-erbB-2 oncoproteins were investigated by immunohistochemical technique using monoclonal antibodies to c-erbB-1 and c-erbB-2 oncoproteins in 43 cases of hasal cell carcinoma (BCC) and 26 cases of squamous cell carcinoma (SCC). The results showed that: ① The expression of c-erbB-1 oncoprotein in BCC increased; the expression of c-erbB-2 oncoprotein in BCC reduced significantly, and lost in 16 cases (16/43). ② The intensities of c-erbB-1 and c-erbB-2 oncoprorein expression had negative and positive correlations to the degrees of SCC differentiation respectively. It is suggested that the abnormal expression of c-erbB-1 and c-erbB-2 oncoprotein in BCC and SCC may play a role in the development of skin tumors.
4.Magnetic resonance imaging of carotid atherosclerotic plaque components
Yanan ZHENG ; Guorong LIU ; Baojun WANG
International Journal of Cerebrovascular Diseases 2013;(1):51-54
Ischemic stroke is closely associated with carotid atherosclerosis.Detecting carotid plaque components (including fibrous Cap,lipid core,hemorrhage,and calcification) using high-resolution 3.0T magnetic resonance imaging contributes to evaluate the risk of ischemic stroke and guide treatment.This article reviews the research status of magnetic resonance imaging of carotid atherosclerotic plaque components.
5.Tube feeding methods in the prevention of stroke-associated pneumonia
Guoqiang CHEN ; Guorong LIU ; Baojun WANG
International Journal of Cerebrovascular Diseases 2013;21(5):389-391
Stroke-associated pneumonia (SAP) refers to the stroke patients suffering from infectious lung parenchyma (including the alveolar wall,i.e.the general pulmonary interstitial) inflammation without previous pulmonary infection.It is one of the most common major complications resulting in death and affecting functional recovery in patients with stroke.Dysphagia resulting in aspiration is the main reason of SAP.Therefore,avoiding aspiration and preventing SAP have important significance for patients with stroke through early correct tube feeding.This article reviews the tube feeding methods of preventing SAP.
6.Effects of alpha-1-adrenergic receptor subtype-selective antagonists on lower urinary tract function in rats with bladder outlet obstruction
Baojun GU ; Feng LIU ; Yuemin XU
Chinese Journal of Urology 2006;0(S1):-
500 mg,frequency was reduced in rats treated with tamsulosin (P500 mg,and the combined ?1a/?1dAR antagonist tamsulosin reduces urinary frequency more than the ?1aAR selective antagonist 5MU.This finding supports the hypothesis that the ?1dAR is important in mediating irritative symptoms.
7.Effect of tumor chemotherapy on cellular immune system
Rui MA ; Xing LIU ; Baojun SAN
Chinese Journal of Practical Internal Medicine 2001;0(06):-
0 05.Only the level of TNF ? decreased obviously at the later stage of chemotherapy,P
8.Diffusion-weighted imaging in transient ischemic attack
Tianming LU ; Guorong LIU ; Baojun WANG
International Journal of Cerebrovascular Diseases 2009;17(6):448-451
Transient ischemic attack (TIA) traditionally refers to temporary brain dysfunction lasting no longer than 24 hours due to a shortage of blood and oxygen, without any residual neurological deficit. In recent years, the development of imaging technology enables us to have a new awareness about TIA. This article reviews the effects of MRI, especially diffusion-weighted imaging, in the diagnosis and prognostic prediction of TIA.
9.The differences in clinical characteristics between health care associated pneumonia and community acquired pneumonia in elderly patients
Geping QU ; Changting LIU ; Baojun SUN ; Xiangqun FANG
Chinese Journal of Geriatrics 2013;(2):149-153
Objective To reveal the differences in clinical characteristics between health care associated pneumonia (HCAP) and community acquired pneumonia (CAP) in elderly patients.Methods A total of 282 elderly patients were evaluated,including 69 patients with HCAP (25.5%) and 213 with CAP (75.5%).A retrospective observational study was conducted.The baseline characteristics,comorbidities,pathogen distribution,antibiotics,and clinical outcomes between HCAP and CAP patients were compared.Results The incidence of chronic obstructive pulmonary diseases and cerebrovascular diseases were higher in HCAP group (49 cases,71.0%; 36 cases,52.2%) than in CAP group (93 cases,43.7%; 57 cases,26.8%) (x2 =15.598,15.229,all P<0.001).The infection of Pseudomonas aeruginosa (29 cases,51.8%),Staphylococcus aureus (19cases,34.0%) and Acinetobacter baumannii (18 cases,32.1%) in HCAP group were more than in CAP group [(26 cases,27.7%),(12 cases,2.8%),(8 cases,8.5%),(x2 =8.796,9.586,13.678,all P<0.05)],respectively.While the infection of Streptococcus pneumoniae (38 cases,40.4%) in CAP group was much more than in HCAP group (4 cases,7.1%)(x2 =19.283,P<0.001).Initial inappropriate antibiotics treatment failure was more frequent in HCAP group (24 cases,34.8%) than in CAP group (37 cases,17.3%)(x2=9.321,P<0.05).The mortality was higher in HCAP group (19 cases,27.5%) than in CAP group (29 cases,13.6%)(x2 =7.151,P<0.05).Conclusions HCAP should be distinguished from CAP in elderly,which is helpful to choose appropriate empirical anti-infective regimen and improve the effect of HCAP treatment.
10.Oxidative stress, oxidized low density lipoprotein, lipoprotein-associated phospholipase A2 and atherosclerosis
Jie YAN ; Guorong LIU ; Yuechun LI ; Baojun WANG
International Journal of Cerebrovascular Diseases 2011;19(3):237-240
Oxidative stress is 811 important risk factor for premature athcrosclcrosis.Itis involved in a variety of pathophysiological processes,including mitochondrial damage,freeradical release,lipid peroxidation,phospholipase activation,and infl~niatory modiator release.A growing body of research suggests that oxidative stress,oxidized low density hpoprotein,andlipoprotein-associated phospholipase A2 Play important roles in the occurrence and developmentof athcrosclcrosis.Therefore,investigating their relationship contributes to deepen theunderstanding of athcrosclerosis and take appropriate preventive measures.