1.Comparison of the karyote detection results of automatic blood analyzer and manual method in special body fluids
Qun CHEN ; Shuping NIE ; Zhicheng ZHANG ; Baojia DENG
International Journal of Laboratory Medicine 2014;(21):2949-2950
Objective To compare the karyote counting and classification results of Sysmex XE-5000 automatic blood analyzer (XE-5000) and manual method in special body fluids .Methods 100 cases of special body fluid specimens (including cerebrospinal fluid and serous cavity effusion) were analyzed ,and the the karyote counting and classification were respectively detected by XE-5000 and the traditional manual method of microscope .Results When the karyote counts were 31-1 000/μL ,there was no signifi-cant difference between XE-5000 and manual method (P>0 .05) .And the karyote counting and classification results of XE-5000 correlated with those of manual method (r=0 .981 ,0 .991 ,P<0 .05) .Conclusion When the karyote counts are 31-1 000/μL ,XE-5000 has good accuracy and high precision in karyote detection in special body fluids .
2.The determination and analysis of CRP and PLT for patients with acute myocardium infarction
Hongmei LIANG ; Hua HUANG ; Baojia DENG ; Zhengwan GUO ; Wei ZHANG
International Journal of Laboratory Medicine 2015;(14):1982-1983
Objective Testing the CRP and PLT for patients with acute myocardium infarction(AMI) .Analysising the relation‐ship between AMI and CPR or PLT .Methods We chose 60 patients with AMI who treat in our hospital during 2012/11 and 2014/10 as an observation group .As the same time ,we also chose 60 healthy person as a comparison group .Testing the CRP and PLT of the two groups with the same method ,and then we compare and analysis the results .Results The observation group's concentration of CRP is (22 .13 ± 4 .71)mg/L ,level of PLT is (241 ± 33)× 109/L .The comparison group's concentration of CRP is(2 .74 ± 0 .49) mg/L ,level of PLT is(162 ± 26) × 109/L .The result of the observation group is obvious higher than the comparison group ,and the difference is significance(P<0 .05) .The observation group's positive rate of CRP is 73 .33% ,increase of PLT is 38 .33% .The comparison group's positive rate of CRP is 3 .33% ,increase of PLT is 5 .00% .The result of the observation group is obvious higher than the comparison group ,and the difference is significance(P<0 .05) .Conclusion To the clinical diagnosis of AMI ,testing the CRP concentration and the PLT level is useful to understand the patient's host defenses and inflammation condition .It has clinical value to AM I's prevent ,diagnosis and prognosis .
3.Clinical significance of changes of platelet parameters and aggregation rate in patients with acute cerebral infarction
Hongmei LIANG ; Hua HUANG ; Baojia DENG ; Zhengwan GUO ; Wanbing TANG ; Zhibiao GAN
International Journal of Laboratory Medicine 2014;(13):1694-1695,1698
Objective To investigate the relationship between platelet maximum aggregation rate(MAR),platelet thrombocyt-ocrit(PCT),platelet count(PLT),platelet distribution width(PDW)and mean platelet volume(MPV)with the course of acute cere-bral infarction(ACI)to provide the basis for its clinical early diagnosis and treatment.Methods 107 patients with ACI in our hospi-tal were selected and divided into the great infarction group(infarction size >10 cm3 ),middle infarction group(infarction size 4-10 cm3 )and small infarction group(infarction size<4 cm3 )according to the infarction lesion size by head CT or MRI and the infarction volume calculated by the Pullicino formula(length×width×layer number/2),40 healthy individuals were selected as the healthy control group.MAR,PLT,PDW,MPV and PCT were detected before and after the induction by PLR-06.Results (1 )Compared with the control group,PLT,PCT,PDW and MPV before the induction by PLR-06 in the great infarction group were obviously in-creased(P <0.01);PLT,PCT,PDW and MPV in the middle and small infarction groups were increased(P <0.05).(2)Compared with the control group,MAR after the induction by PLR-06 in each infarction group was increased(P <0.05);PLT had no statisti-cal difference among the groups(P >0.05 );PCT,PDW and MPV in the great and middle infarction groups were increased(P <0.05);PCT,PDW and MPV in the small infarction group had no statistical differences(P >0.05).Conclusion The change of the platelet aggregation rate,number and volume is closely related with the occurrence and development of ACI,monitoring their change has important clinical significance to prevention and treat ACI.