52 patients (46 males, 6 females) with esophageal varices bleeding, age from 19-84 years, who were treated at the Central Military hospital 108 from September 2002 to September 2003. The level of breakdown via endoscopy and the number of esophageal varices breakdown on 52 patients included: 5 cases with mild level, 13 cases with average and 34 cases with severe level; 7 patients at grade II, 45 grade III; 59.6% of patients in the first time of bleeding, 21.6% secondly and 19.2% ≥3 times. Treatment results: 71.2% patients had a complete hemostasis; recurrent rate was 57.7%, in which the rate was 9.6% during first month. For 2 years of followed up, mortality rates one month and 2 years after were 13.3% of 57.7%, respectively. The results indicated that the endoscopic varices ligation have good effectiveness in urgent hemostatic cases but ineffectiveness in long-term outcome.
Gastrointestinal Hemorrhage ; Esophageal and Gastric Varices ; Therapeutics

Growing increase in resistance of H. pylori strains to antibiotics of choice is identified worldwide, requiring further investigating susceptible characteristics of the germ to these agents. Objectives: To assess the resistance of H. pylori individual colonies from a single biopsy to metronidazole and clarithromycin. Methods: The E - test was used to determine the Minimum Inhibitory Concentrations (MICs) of these two antimicrobial drugs for ten H. pylori colonies isolated from an initial gastric biopsy culture from each of 14 adults and 14 children. Results: Among patients haboring HP strains resistant to these 2 antimicrobials, we observed heterogeneity in metronidazole resistance in 14/22 cases and in clarithromycin resistance in 3/13 cases. The number of resistant individual colonies ranged from 2/10 to 9/10 depending on subjects. Conclusions: In the same biopsy from both adults and children different colonies of H. pylori displayed different antimicrobial susceptibility patterns prior to anti - H. pylori treatment, rendering antibiogram interpretation difficult.
Helicobacter pylori, Adult, Child, Metronidazole

The surveillance of medicinal material market was conducted in NinhHiep market, LanOng street in Hanoi and in LangSon Province showed that the regulation of storage and circulating of medicinal material was not complied with only 9/31 samples (29,03%) met Vietnam PharmacopeaeIII standards. Only 17/39 imported samples met the standards of VN or China Pharmacopeae. Validity date must be standardized completely. The Regulation of Control of Medicinal Materials including periodical regular control must be issued by MOH for the whole country market
Chemistry, Pharmaceutical ; Plants, Medicinal ; Health Care Sector

On experimental model CCl4-induced hepatitis the effect on liver enzyme GPT and bilirubine level of 10 aqueous extracts from traditional medicinal plants was studied in combining with sylymarin extracted from semen of immigrant Cuc Gai (Sylibum marianum Gaertn.). Extracts of Bantron (Hypericum patulum Thunb.ex Murr.),Nhodong (Morinda longissima Y.Z.Ruan),Raudang(Polygonum aviculare),and silymarin with their hepatoprotective effect can be use clinically. Ma De (Plantago asiatica L.) extract can be used to reduced GPT liver enzyme and bilirubine level, its F2C fraction can reduce GPT and bilirubine, similarly with silymarin of CucGai. The combined preparation of Ma De F2C and silymarin can be used as supporting therapeutic for chronic hepatitis
Plants, Medicinal ; liver ; prevention & control ;

Product from Bitter tea collected at Cao Bang was studied on antioxidant activities, as well as anti-hepatitis, anti-cirrhosis effects in vivo in the model of cirrhosis mice. Results showed that total saponin extracted from Bitter tea had antitoxic, hepatoprotective, and anti-hepatitis effects, and cirrhosis inhibition
Medicine, Traditional ; plants, medicinal ; liver ; Tea ; Hepatitis ; Fibrosis

At Bach Mai hospital,on 824 pediatric sutbjects aged 6 months – 15 years, the infuence of previously used antibiotics on serological results of the epidemiological diagnosis of Helicobacter pylory infection was evaluated. Among 731 studied children using antibiotics, there was HP (+) in 34,6%. There was no significant relation between the use/no use of antibiotics and HP infected. serological results.There was no same relation between the moment, the frequency,the duration and the antibiotherapy use with the results of serological diagnosis of HP infection
Helicobacter pylori ; child ; Anti-Bacterial Agents

In this study, fine needle aspiration cytopuncture (FNAC) was done for 220 patients with liver tumors. The findings showed that FNAC was of high value in diagnosis of Hepatocellular Carcinoma (HCC). Successful first time of FNAC was 93.2%. The accurate rate 97.7%, sensitivity 97.3% and specificity 100%. 19.6% patients were in well differentiated; 47.7% average differentiated and 32.7% poor differentiated. 86.7% tumor under 3cm in diameter with well-differentiation and 86.7% tumor over 9cm in diameter with poor-differentiated. The FNAC is simple, easy performing and safe method
Carcinoma, Hepatocellular, Diagnosis

A study on 56 patients with chronic hepatitis B who were divided into 2 groups: study group and control group. The study group including 31 patients was treated with Thymosin-α1 1.6mg/day, twice a week for 6 months. The control group with 25 patients of same clinical data was treated with common liver-protective drugs. Both groups were monitored and assessed after 24 months. The results showed that the study group with treatment of Thymosin-α1 is better than control one in all aspects of ALT normalization, sero-conversion and decrease of HBV-DNA<5 copies/ml
Hepatitis B, Chronic ; Therapeutics

A prospective study on 50 patients with irritable bowel syndrome (IBS) at Gastroenterology Department of Central Military Hospital 108 between June 2003 and June 2005. Results showed that the common clinical features of IBS were: abdominal pain (100%), untaste in abdominal cavity (96%), bowel disturbance (100%), flatulence (72%). The relative factors causing IBS consisted of intellectual work (72%), eating much lipid (36%), stinking food (30%) and smoking (16%). The Rome II criteria were applied effectively in the diagnosis of IBS. Three main criteria with very high rates were: 92% pain relieve of bowel movement, 68% pain related to the change of bowel movement frequency and 96% pain related to the change of faeces shape
Irritable Bowel Syndrome ; Clinical Medicine

In the study, 166 patients (125 men, 41 women) with acute pancreatitis were treated at Central Military Hospital 108 from August 2003 to August 2005. The common clinical symptoms of acute pancreatitis were epigastrium severe pain 100%, continuous or interrupted pain; localize or spread; fever 51.2%; vomiting 35.5%; abdominal gas 92.8%; peritoneal hypersensitive 92.8%. Among the patients, 90.4% were mild and average; 9.6% were severe. Paraclinical features included a high concentrate of serum and urine amylase (96.4 and 94%, respectively) at different levels that was not relative with the severity; 50% of the patients had big pancreas in ultrasonography. The common causes of acute pancreatitis were big meal with drinking 24.1%, bile stones 13.2%, ascarid in bile tract 9.6% and some other causes; unknown causes 38.7%
Pancreatitis ; Clinical Medicine