1.Septal turbinates: An entity with physiological importance.
Mawaddah AZMAN ; Balwant Singh GENDEH
Brunei International Medical Journal 2011;7(3):168-172
Septal turbinate refers to a widened region of the septum located superior to the inferior turbinates and anterior to the middle turbinates. Although a common anatomical variant, its significance is not well reported. We report a 56-year-old Malay man who presented with a three year history of chronic nasal obstruction secondary to septal turbinate and type II deviated nasal septum. His nasal symptoms improved dramatically following commencement of intranasal steroids. He remained free of symptoms during seven years of follow up. The physiologic implication and management of septal turbinates is discussed.
2.Sensitisation to common allergens in children with allergic rhinitis.
Farah Dayana ZAHEDI ; Balwant Singh GENDEH ; Salina HUSAIN
Brunei International Medical Journal 2011;7(4):200-206
Introduction: Allergic rhinitis is common in otorhinolaryngology practice. According to ‘Allergy Rhinitis and its Impact on Asthma (ARIA), Clinical and Experimental Allergy Reviews’ guidelines, the management of allergic rhinitis includes allergen avoidance. Therefore, it is important to know the allergens to which the patient is sensitised. This study was carried out to determine the prevalence of sensitisation to common allergens among children with allergic rhinitis seen in a tertiary referral centre in Malaysia. Materials and Methods: All children aged five to 12 years who had been referred to Otorhinolaryngology clinic Universiti Kebangsaan Malaysia Medical Center (UKMMC) from 2005 to 2010 with symptoms consistent with allergic rhinitis and had a skin prick test (SPT) were included in the study. The common allergens that had been used in the SPT were aeroallergens, food allergens and contact allergens. The database of SPT results was collected and reviewed. Results: A total number of 580 children were included in this study with 69.3% showing positive SPT. From the positive SPT results, a total of 1,515 sensitisations were observed with 60.9% sensitised to aeroallergens, 38.6% sensitised to food allergens and 0.6% sensitised to contact allergens. Among the aeroallergens, the house dust mite accounted for more than half of the sensitisations: Dermatophagoides pteronyssinus (27.9%), Dermatophagoides farinae (26.4%), Blomia tropicalis (26.0%). The most common food allergen sensitisation was seafood – crab (18.5%), prawn (18.0%) and squid (8.7%). Each of the other food allergens tested accounted for less than five percent of the positive SPT result. The contact allergen tested in this study was latex. Conclusion: This data represents a common allergen sensitisation in children with rhinitis symptoms residing in urban areas with house dust mites being the most common allergen sensitised in these children.
3.Endonasal Endoscopic Transsphenoidal Pituitary Surgery for Pituitary Adenoma: A retrospective Analysis Of Surgical Outcome
Mohd Sazafi Mohd Saad ; Balwant Singh Gendeh ; Salina Husain
The Medical Journal of Malaysia 2011;66(5):443-446
The purpose of this retrospective joint rhino-neurosurgical
study from January 1998 until September 2009 is to
document the demographic data, clinical presentations,
radiological findings, approaches and incidence of residual
tumour. Forty-seven patients with pituitary adenoma
underwent trans-sphenoidal hypophysectomy of which 25
patients with complete medical and radiological data were
included in the study. The medical and radiological data
were analyzed. There were 12 males and 13 females with
age ranging from 17 to 76 years old (mean 49.2). Fourteen of the patients were Chinese, eight Malays and three Indians. Twelve of the patients had functioning tumour of which five each presented with acromegaly and Cushing disease respectively and two with amenorrhoea. The rest of 13 patients had non functioning tumour presenting with visual disturbances. Sixteen of the patients had pituitary
macroadenomas and the rest 9 microadenomas. Eighteen
patients had undergone transcollumellar trans-sphenoidal
hypophysectomy and the rest 7 patients had undergone
transnasal transsphenoidal hypophysectomy. About 68.8%
of pituitary macroadenomas had residual tumour, compared
to only 22.2% of patient with pituitary microadenomas.
Radiologically, about 45.5% of residual macroadenoma had
suprasellar extension and the majority had spread to
suprasellar cistern and carvenous sinus (54.5%). About
16.6% of patients had undergone post operative
radiotherapy. In conclusion, this study showed that patient
with pituitary macroadenomas had higher incidence of
residual tumour compared to pituitary microadenomas
4.Caring for the dying in a developing country, how prepared are we?
Hardip Singh Gendeh ; Avinesh Singh Bhar ; Manvin Kaur Gendeh ; Hayati Yaakup ; Balwant Singh Gendeh ; Nik Ritza Kosai ; Ramzisham bin Abdul Rahman
The Medical Journal of Malaysia 2016;71(5):259-263
End of life care is framework to allow for a peaceful,
comfortable and dignified death while considering the
patients’ personal and religious values, bioethics and
knowledge of the disease process. A well planned end of life
pathway should allow for the flexibility to shift from an active
(or aggressive) treatment approach to one of comfort and
care when initial interventions have failed. The need for this
pathway is most apparent in the intensive care setting.
Implementation of a pathway will face various challenges
due to religious and cultural beliefs, education of healthcare
providers to carry out difficult discussions and larger
socioeconomic implications. Clear medico-legal framework
will be required to support this pathway. In conclusion, an
end of life pathway tailored to our local needs is the way
forward in allowing for dignified death of terminally ill
patients; this will require the active participation of medical
societies, religious leaders, healthcare providers, patients
and their care givers.
5.Follicular thyroid cancer with sternal metastasis - challenges and outcomes
Muhammad Adi Syazni ; Hardip Singh Gendeh ; Nik Ritza Kosai ; Mohd Ramzisham Abdul Rahman ; Balwant Singh Gendeh ; Normala Basiron ; Farrah Hani Imran
The Medical Journal of Malaysia 2017;72(1):80-82
Sternal metastasis from differentiated thyroid carcinoma
(DTC) is rare and presents a conundrum for surgeons. We
present a lady diagnosed with follicular thyroid carcinoma
and sternal metastasis who underwent thyroidectomy,
sternectomy and sternoplasty with titanium mesh and
acrylic plate. She developed a surgical site infection, of
which multiple conservative approaches were attempted.
She eventually required removal of the implant. Closure of
sternal defect was completed with bilateral pectoralis major
advancement flaps. This article highlights a series of
complications faced during the course of treatment and how
they were managed in a tertiary healthcare centre.
Adenocarcinoma, Follicular
6.Quality of life and recurrence of disease in patients with eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyposis
Nor Khairina KHAIRUDDIN ; Salina HUSAIN ; Balwant Singh GENDEH ; Aneeza Khairiyah Wan Hamizan ; Valerie LUND
The Medical Journal of Malaysia 2018;73(1):1-6
Objective: To assess the quality of life (QoL) and recurrenceof disease in patients with eosinophilic (ECRSwNP) andnon-eosinophilic chronic rhinosinusitis with nasal polyposis(non-ECRSwNP) post endoscopic sinus surgery (ESS).Methodology: A cross-sectional comparative study wascarried out in the Otorhinolaryngology – HNS Department,Universiti Kebangsaan Malaysia Medical Center (UKMMC).Subjective assessments of nasal symptoms and quality oflife (QoL) using SNOT-22 and Visual Analogue Scale (VAS)and objective endoscopic assessment was undertakenusing a modified Hadley endoscopic examination.Results: There was no significant statistical difference in thequality of life between the ECRSwNP and non-ECRSwNPgroups as evidenced by the SNOT-22 score and the VAScomparison (p>0.05). However, there was a significantdifference in terms of recurrence of disease with thepresence of nasal polyps on endoscopic examination. (p =0.016)Conclusion: In conclusion, we found that there is nosignificant difference in QoL between ECRSwNP and nonECRSwNP.There is higher frequency of recurrence of nasalpolyps amongst ECRSwNP.
7.Five cases of iatrogenic cerebrospinal fluid (CSF) rhinorrhoea: Early management is crucial
Aidayanti DAUD ; Salina HUSAIN ; Balwant Singh GENDEH ; Farah Dayana ZAHEDI ; Faizah Mohd ZAKI
The Medical Journal of Malaysia 2018;73(4):249-252
Endoscopic sinus surgery (ESS) is a standard treatment forrhinosinusitis, which failed optimum medical therapy.Iatrogenic cerebrospinal fluid (CSF) rhinorrhoea can occurduring ESS warrants early repair of the leakage. Thecommon sites for CSF leakage are cribriform plate, foveaethmoidalis, and anterior ethmoid sinuses. We present fivecases of iatrogenic CSF rhinorrhoea due to ESS and itsmanagement.
8.Tube extrusion and cheese wiring five years post dacryocystorhinostomy.
Khairullah Bin Anuar ; Balwant Singh Gendeh
Philippine Journal of Otolaryngology Head and Neck Surgery 2011;26(2):25-27
OBJECTIVE: Dacrocystorhinostomy (DCR) with silicone tube stenting is a common procedure for congenital nasolacrimal duct obstruction (NLDO). The incidence of congenital NLDO is about 6% in the newborn. The duration the tube is left in place varies depending on surgeon preference. Cheese wiring is one of the tube-related complications when the tube is left behind for a long duration. The term cheese wiring refers to the silicone stent or tubing cutting through soft tissue close to the punctum or canaliculi like wire cuts through cheese. We present a case of tube extrusion with cheese wiring five years post DCR.
METHODS:
Design: Case report
Setting: Tertiary Referral Center
Patient: One
RESULTS: A 16-year-old Indian male with congenital bilateral NLDO underwent right and left DCR at ages 9 and 11, respectively. The patient presented with smelly nasal discharge five years later to the ENT clinic. On initial examination the right tube was in place but the left tube was not visualized. Nasal endoscopy however revealed that both tubes were still there and were subsequently removed.
CONCLUSION: DCR with silicone intubation is a common practice. Early follow up is essential to prevent complications. If tube extrusion is suspected, early endoscopic examination is essential to confirm it.
Human ; Male ; Adolescent ; Infant Newborn ; Nasal Obstruction ; Lacrimal Duct Obstruction ; Dacryocystorhinostomy ; congenital ; Stents ; complications ; Endoscopy
9.Respiratory epithelial adenomatoid hamartoma of the nasal septum
Siti Zulaili Zulkepli ; Salina Husain ; Balwant Singh Gendeh
Philippine Journal of Otolaryngology Head and Neck Surgery 2012;27(1):28-30
Objective:
Hamartomas are relatively uncommon, non-neoplastic malformations indigenous to the involved anatomic site. Respiratory epithelial adenomatoid hamartoma (REAH) is a subset
of hamartoma characterized by prominent glandular proliferation lined by ciliated epithelium originating from the surface epithelium. Their location in the nasal cavity is rare and when present, mostly associated with the posterior nasal septum. We present such a case arising from the anterior nasal septum.
Methods:
Design: Case report
Setting: Tertiary University Referral Center
Patient: One
Results:
A 32-year-old lady who presented with a long-standing nasal block was found to have a broad-based nasal mass arising from the left anterior nasal septum. The lesion was histologically
diagnosed as respiratory epithelial adenomatoid hamartoma following surgical excision.
Conclusion
Respiratory epithelial adenomatoid hamartoma although rare must be taken into
consideration in the differential diagnosis of nasal lesions.
Human
;
Female
;
Adult
;
HAMARTOMA
;
NEOPLASMS
;
NASAL SEPTUM
;
Nasal Obstruction
;
DIAGNOSIS
;
nose
;
respiratory system
10.Extramedullary plasmacytoma of the nasopharynx: A rare tumour with 7-year follow up
Mawaddah Azman ; Balwant Singh Gendeh ; Siti Aishah Mat Ali
Philippine Journal of Otolaryngology Head and Neck Surgery 2011;26(1):27-30
Objective:
To report a case of extramedullary plasmacytoma, a rare localized tumour involving the head and neck region in a 56-year -old gentleman.
Methods:
Design: Case Report
Setting: Tertiary University Referral Center
Patient: One
Result:
The patient presented with a 5-month history of right-sided nasal obstruction and intermittent epistaxis in 2003. Nasal endoscopy revealed a friable, dark red mass arising from the roof of the nasopharynx, occluding the right choana. No invasion of adjacent tissues or cervical lymphadenopathy was evident. A biopsy of the mass was diagnosed as plasmacytoma. Serum and urine electrophoresis failed to detect any monoclonal bands. All other screening tests to rule out multiple myeloma were negative. These findings confirmed the diagnosis of extramedullary plasmacytoma. He recieved radiotherapy to the nasopharynx of 50 Gy for a total of 23 fractions. No recurrence was noted at 7-year follow-up.
Conclusion
Extramedullary plasmacytoma of the nasopharynx represents a tumour with good prognosis but requires long term follow up in anticipation of local recurrence and progression to Multiple Myeloma.
Plasmacytoma
;
Nasopharynx