1.Antitumor action of methylene blue
Qitai XU ; Gangjun DU ; Baiquan CHEN ;
Chinese Pharmacological Bulletin 1987;0(03):-
2.Application of VPN technology to PACS
Weijiang ZHAO ; Lixin CHEN ; Baiquan ZHENG ; Jufeng SHEN
Chinese Medical Equipment Journal 1993;0(06):-
Objective To explore the application of the virtual private network(VPN) to picture archiving and communication system(PACS) for the remote access and management of PACS.Methods The client-ports(namely the remote computers) were connected to Internet by broadband such as ADSL,and the web server of PACS was connected to Internet by broadband router with VPN function so that the remote computers could access the web server of PACS remotely.By the VPN technology,the system administrators of PACS could diagnose and maintain the general malfunctions of the radiology's local network,and thus the remote management came true.Results The remote access and management of PACS had been available in our hospital for half a year since the application of the VPN technology in PACS.By more convenient medical services the work efficiency had been greatly improved.Conclusion The application of VPN technology to PACS,which is characterized by low expense,dependable performance,simple maintenance,can realize remote access and management of PACS.
3.The influence of insulin resistance and insulin secretion in women with glucose intolerance during late pregnancy
Yuzhu YIN ; Jianhui FAN ; Xiaowei CHEN ; Hongying HOU ; Baiquan JIANG
Journal of Chinese Physician 2001;0(09):-
Objective To investigate the relationship of insulin resistance and secretion during late pregnancy in women with glucose intolerance.Methods Immunoenzymetric assay was used to measure the fasting serum insulin levels in 122 pregnant women which including of 36 pregnant women with gestational diabetes mellitus(GDM),34 pregnant women with gestational impaired glucose tolerance(GIGT),and 52 pregnant women with normal glucose tolerance(NGT).The fasting plasma glucose levels were measured by glucose oxidase method.The insulin sensitivity index(ISI) and islet secretive function index(IFI) were compared between the three groups.Results ISI had an increasing trend from NGT group,GIGT group to GDM group(P
4.Effect of lacidophilus exopolysaccharides on immunity
Qitai XU ; Yu ZHANG ; Gangjun DU ; Baiquan CHEN ; Cuiping BAO
Chinese Pharmacological Bulletin 2003;0(12):-
Aim To study the effect of Lacidophilus exopolysaccharides(LAEPS) on immunity. Methods Effects of LAEPS on immunity were investigated by delayed type hypersensitivity reaction, haemolytic plaque assay and macrophage function assay in mice. Results LAEPS ip 7~8 day promoted delayed type hypersensitivity reaction, increased haemolytic plaque and enhanced macrophage function in a dose-dependent manner.Conclusion LAEPS is able to enhances immunity.
5.Alpha-glucosidase inhibitory active constituents contained in nutshell of Trapa acornis.
Baiquan CHEN ; Qian ZHANG ; Wei WANG ; Huan HUANG ; Wenyi KANG
China Journal of Chinese Materia Medica 2012;37(10):1408-1411
OBJECTIVETo study chemical constituents in nutshell of Trapa acornis and in vitro inhibitory activity against alpha-glucosidase.
METHODEtOAC and n-butanol extractive fractions were separated by chromatography and their structures were identified by multiple spectroscopic techniques.
RESULTNine compounds were separated, they were 4,23,24-trimethylcholest-22-en-3-ol (1), stigmasterol (2), alpha-amyrin (3), (+)-nyasol (4), oleanolic acid (5), ursolic acid (6), hederagenin (7), 3,23-dihydroxy-12-ursen-28-oic acid (8) and beta-daucosterol (9). Total extracts from T. acornis nutshells, petroleum ether fractions, acetic ether fractions and normal butanol fractions showed inhibitory activity against alpha-glucosidase. Compound 5 (IC50 2.88 mg x L(-1)) and 6 (IC50 4.42 mg L(-1)) showed stronger inhibitory activity against alpha-glucosidase.
CONCLUSIONAll compounds except compound 2 were separated from the genus for the first time, and compound 1-9 were separated from this plant for the first time.
Enzyme Inhibitors ; chemistry ; Glycoside Hydrolase Inhibitors ; Lythraceae ; chemistry