ve To explore the levels of boood lead of preschool children in Harbin and their impacts on the growth and development of children. Methods 310 preschool children aged 4~7 years were selected for measurement of height and weight, and for collection of fasting blood samples, determined for concentrations of lead by ICP/ MS assay. The state of lead poisoning in selected subjects was defined based on the blood lead level of ?100?g/L ruled by the standard of children's lead poisoning established by CDC in 1991 and Health Assessment Scale for Growth and Development of Children set by Academy of Preventive Medicine. Results The prevalance rate of lead poisoning a-mong selected preschool children was 14.9%. Significantly negative correlation was observed between the blood lead levels and heights (H), body weights(BW) in children aged 4~5 years (rBw = -0.158, P