No abstract available.
Meningitis, Bacterial*

No abstract available.
Vaginosis, Bacterial*

No abstract available.
Meningitis, Bacterial*

Aims: This study aims to investigate the phylogroups, antibiotics susceptibility and biofilm formation among CVEC isolated from female with bacterial vaginosis. Methodology and results: High vaginal swab from girl with age (18-60 years) were collected and cultured on MacConkey agar, EMB agar and UTI chromogenic medium to recover CVEC and only the confirmed Escherichia coli will pass through rest of the assays like phylogrouping (by PCR), antibiotics susceptibility test and biofilm formation. The results revealed that only 32 (20.38%) of CVEC were recovered and among them only 3 (9.375%) of CVEC belong to intestinal subgroup A1 and the rest 29 (90.625%) assigned to extraintestinal phylogenetic group B2. CVEC isolates belong to B1 and D groups not reported. Antibiotics resistance results shown that, 32 (100%) for cefazolin, cephalothin, cefoxitin and metronidazole, 31 (96.9%) for erythromycin, 24 (75%) for fosfomycin, 20 (62.5%) for cefotaxime, 16 (50%) for ceftazidime, 14 (43.75%) for cefepeim, (28.1%) for aztreonam, 7 (21.9%) for streptomycin, 6 (18.75%) for meropenem, 5 (15.6%) for both imipenem and gentamicin, 2 (6.25%) for both ciprofloxacin and norfloxacin, amikacin 1 (3.1%) and no resistance stated for nitrofurantion (0.00%). TCP methods results display that 12 (37.5%) of CVEC were biofilm former while 20 (62.5%) were non biofilm former. Conclusion, significance and impact of study: This study concluded that, most of the CVEC belong to highly virulent phylogroup B2 and have the ability to resist multiple antibiotics and the ciprofloxacin, norfloxacin, amikacin and nitrofurantion still the best choice for treatment and CVEC have the ability to form biofilm which make the infection ruthless and hard to cure.
Vaginosis, Bacterial

INTRODUCTION: This study aimed to determine the in vitro susceptibility of standard isolates of common pathogens causing bacterial conjunctivitis to non-fluoroquinolone antimicrobial ophthalmic medications. METHODS: This is a single-blind experimental study which compared the in vitro susceptibility of Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa and Staphylococcus epidermidis to locally available non-fluoroquinolone ophthalmic medications, specifically chloramphenicol, tobramycin, fusidic acid, gentamicin sulfate, sulfacetamide and polymyxin-neomycin. Utilizing the disk diffusion method, zones of inhibition in millimeters for each bacterial isolate was recorded and tabulated. Kruskal-Wallis test was used to determine statistical differences. RESULTS: Both Staphylococci were sensitive to all antibiotics except sulfacetamide. Only chloramphenicol showed activity against all four isolates. Tobramycin showed the largest zone of inhibition against Pseudomonas aeruginosa. There was statistically significant difference in the median zone of inhibition in each antimicrobial medication against Staphylococcus aureus (p = 0.002) and Staphylococcus epidermidis (p < 0.001) with the largest mean zone of inhibition by fusidic acid of 34 and 38 millimeters, respectively. Streptococcus pneumoniae was least susceptible to antibiotics tested; only chloramphenicol and fusidic acid showed activity. There were also significant differences in the median zones of inhibition across the isolates. CONCLUSION The standard isolates are susceptible to at least one non-fluoroquinolone ophthalmic medication. The antibiotics tested showed differences in activity against the four isolates. The findings of this study may be used as a basis to review local practice patterns or/and initiate revisions in the guidelines for prescribing initial treatment of bacterial conjunctivitis.
Conjunctivitis, Bacterial ; Anti-Bacterial Agents

The entry of gastric carcinoma cells ASG via the interaction of the vesicles of Helicobacter pylori VNH-85 strain was studied. The results showed that: The vesicles of Helicobacter pylori contained many protein toxins such formed from the outer membrane of bacterium H. pylori. The entry of them into gastric carcinoma cells ASG C120 led to increased synthesis of interleukin IL-8. So that, protein CagA could enter into gastric epithelium cells via interaction of bacteria, into gastric epithelium cells, protein CagA increased synthesis of interleukin IL-8 over 8 times.
Helicobacter pylori ; Cells ; Antigens, Bacterial ; Bacterial Proteins

Study was performed on 100 serum samples of patients (15-70 aged) treated of gastro-duodenal diseases and 31 healthy persons by Immunoblot assay. The results showed that: the prevalence of H.pylori positive in patients with gastric ulcer, duodenal ulcer and gastritis was 76.5, 95.8 and 73%, respectively. The prevalence of H. pylori seropositive was found 64.5% in healthy persons. The prevalence of anti-CagA and anti-VacA antibodies was 86.2% and 60.6% (respectively) in patients and was 70% and 40% (respectively) in healthy person.
Antigens, Bacterial ; Bacterial Proteins ; Helicobacter pylori ; Antibodies ;

No abstract available.
Anti-Bacterial Agents*

No abstract available.
Anti-Bacterial Agents* ; Phagocytosis*

Target controlled infusion(TCI) is an infusion system which allows the anesthetist to select the target blood concentration required for a particular effect and then to control the depth of anaesthesia by adjusting the requested target concentration, which includes the instantaneous calculation of the infusion rate necessary to obtain and maintain a given therapeutic blood concentration of drug based on average pharmacokinetic parameters. We can apply this concept of infusion system not only to anesthetics but also to any kinds of intravenous drug infusion including antibiotics in the future.
Anesthetics ; Anti-Bacterial Agents