Introduction: Non-Hodgkin’s lymphomas (NHLs) are a varied group of malignancy originating in the lymphatic system. As a subset of lymphomas, primary spinal epidural lymphomas are diagnosed when there are no other recognizable sites of lymphomas at the time of diagnosis. It mimics other spinal diseases making the diagnosis difficult to establish as well as in obtaining tissue diagnosis. We present an atypical case of a 45-year-old female who presented initially with back pain then eventual loss of sensory and motor function of the lower extremities, further work up showed primary spinal epidural NHL. Case: This is a case of a 45-year-old female with chief complaint of back pain. Magnetic resonance imaging (MRI) of the thoracic spine showed nonspecific epidural soft tissue mass at T5 to T6 level compressing the spinal cord. Operative procedure was done with histopathology of the epidural lesion consistent of NHL. Immunohistochemical staining showed CD20 (+), thus a diagnosis of diffuse large B cell lymphoma (DLBCL) was made. Patient underwent six cycles of cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) regimen. Conclusion Signs and symptoms of primary spinal epidural NHL often overlaps its manifestations with other spinal diseases. A high index of clinical suspicion warrants inclusion of such neoplastic condition in determining the exact and definitive diagnosis of cases manifesting spinal compression.
Back Pain

Low back pain is an extremely common symptom. Approximately 80% of the general population experience a memorable episode of back pain in their lives. The patients suffering from chronic low back pain have a poor prognosis, with only 20~40% of them improve with multiple treatment trials. Chronic low back pain has various underlying causes, and about 40% are discogenic. The vast majority of patients are treated successfully with nonsteroidal anti-inflammatory medications and physical therapy. However, the number of the minority of patients who fail to respond to these conservative measures is still substantial. When conservative managements fail after a period of months, surgical treatment options should be considered.
Back Pain ; Humans ; Low Back Pain ; Prognosis

Low back pain is an extremely common symptom. Approximately 80% of the general population experience a memorable episode of back pain in their lives. The patients suffering from chronic low back pain have a poor prognosis, with only 20~40% of them improve with multiple treatment trials. Chronic low back pain has various underlying causes, and about 40% are discogenic. The vast majority of patients are treated successfully with nonsteroidal anti-inflammatory medications and physical therapy. However, the number of the minority of patients who fail to respond to these conservative measures is still substantial. When conservative managements fail after a period of months, surgical treatment options should be considered.
Back Pain ; Humans ; Low Back Pain ; Prognosis

BACKGROUND: Low back pain (LBP) is a major problem for office workers. Individuals adopting poor postures during prolonged sitting have a considerably increased risk of experiencing LBP. This study aimed to investigate seat pressure distribution characteristics, i.e., average pressure, peak pressure ratio, frequency of postural shift, and body perceived discomfort (BPD), during 1 hour of sitting among office workers with and without chronic LBP. METHODS: Forty-six participants (chronic LBP = 23, control = 23) typed a standardized text passage at a computer work station for an hour. A seat pressure mat device was used to collect the seat pressure distribution data. Body discomfort was assessed using the Body Perceived Discomfort scale. RESULTS: Office workers with chronic LBP sat significantly more asymmetrically than their healthy counterparts. During 1-hour sitting, all workers appeared to assume slumped sitting postures after 20 minutes of sitting. Healthy workers had significantly more frequent postural shifts than chronic LBP workers during prolonged sitting. CONCLUSION: Different sitting characteristics between healthy and chronic LBP participants during 1 hour of sitting were found, including symmetry of sitting posture and frequency of postural shift. Further research should examine the roles of these sitting characteristics on the development of LBP.
Low Back Pain* ; Posture

No abstract available.
Diagnosis* ; Low Back Pain*

No abstract available.
Leg* ; Low Back Pain*

No abstract available.
Incidence* ; Low Back Pain*

No abstract available.
Animals ; Back Pain* ; Lordosis*

No abstract available.
Back Pain* ; Cysticercosis*

No abstract available.
Humans ; Low Back Pain*