1.Risk factors and complications of acute ischaemic stroke patients at Hospital Universiti Kebangsaan Malaysia (HUKM).
The Medical Journal of Malaysia 2003;58(4):499-505
In Malaysia, there is limited information on the mortality and morbidity after an acute stroke in hospitalised patients. The objective of the study was to identify the type, time of onset, and frequency of medical and neurological complications following an acute ischaemic stroke. Consecutive patients with acute ischaemic stroke who were admitted to Hospital Universiti Kebangsaan Malaysia from June 2000 to January 2001 were observed. The complication rate was 20.9%. The most common individual complication was pneumonia (12.3%), followed by septicaemia (11.0%), urinary tract infection (4.3%), and upper gastrointestinal haemorrhage (3.7%). The overall mean length of stay was 7.48 days. The independent risk factors for complications were diabetes mellitus (OR 2.87; 95%CI 1.06 to 7.78), middle cerebral artery (MCA) infarcts (OR 10.0; 95%CI 4.1 to 24.3), and Glasgow coma score (GCS) less than 9(OR 3.8; 95%CI 1.03 to 14.3). Infection was the commonest complication observed. Patients with diabetes mellitus, poor GCS and large MCA infarcts had a higher risk of developing complications.
Acute Disease
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Cerebrovascular Accident/*complications
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Chi-Square Distribution
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Hospitals, University
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Length of Stay/statistics & numerical data
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Malaysia
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Prospective Studies
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Risk Factors
3.A Rare Case of Traumatic Bilateral Sixth Cranial Nerve Palsy
The International Medical Journal Malaysia 2012;11(2):50-52
Traumatic bilateral sixth cranial nerve palsy is a rare condition which is typically associated with additional
intracranial, skull, and cervical spine injuries. We describe a case of complete bilateral sixth nerve palsy in
a 28-year-old female patient after an alleged motor vehicle accident. She had altered level of consciousness
but no intracranial lesion or associated skull or cervical spine fracture was detected. In this case, we discussed
the differential diagnoses, initial workup, and possible treatment options in cases of traumatic 6th nerve palsy.
4.Predictors of Stroke-associated Pneumonia after the First Episode of Acute Ischaemic Stroke
AT Nor Adina ; MA Ahmad ; A Uduman ; BB Hamidon
Malaysian Journal of Medicine and Health Sciences 2012;8(1):37-43
Objectives: Pneumonia is one of the most common complications of stroke with significant impact on
patients’ outcome. The aim of this study is to look for the predictors of stroke-associated pneumonia
(SAP) and its 30-day mortality and to analyse the survival of ischaemic stroke patients with pneumonia.
Methodology: This is a prospective observational study, involving all acute first time ischaemic stroke
patients admitted to a tertiary hospital that fulfilled the inclusion and exclusion criteria over a 6-month
period. Demographic data were obtained on admission. Patients were reassessed for SAP, on day 5
and day 30. Assessment was done using the National Institutes of Health Stroke Scale (NIHSS) score,
Barthel index and modified Rankin scale (MRS). All patients with pneumonia were assessed with the
pneumonia severity index (PSI) for SAP. Results: One hundred and twenty patients were enrolled
consecutively within the 6-month study period. 15.8% developed SAP. Independent predictors of
SAP were clinical dysphagia (OR 76.32; 95%CI 4.46 to 1307.05), random blood glucose (RBS) on
admission (OR 1.34; 95%CI 1.06 to 1.68) and NIHSS score on admission (OR 1.15; 95%CI 1.02 to
1.30). Independent predictors for 30-day mortality were NIHSS score on day 5 (OR 1.20; 95%CI 1.08
to 1.33) and occurrence of pneumonia (OR 14.90; 95% CI 3.34 to 66.42). There was a significant
difference in mean survival between SAP and non-SAP patients. Conclusions: Clinical dysphagia, RBS
on admission and NIHSS score on admission were independent predictors of SAP. NIHSS score on day
5 and pneumonia were independent predictors of 30-day mortality. SAP patients had shorter survival
time compared to non-SAP patients.