1.A prognostic analysis of paroxetine in treatment patients with poststroke depression and anxiety
Chinese Journal of Primary Medicine and Pharmacy 2010;17(21):2953-2955
Objective To study the efficiency,safety,and its impact on the functional rehabilitation of the selective 5-serotonin reuptake inhibitor(SSRI) drugs paroxetine in treatment patients with poststroke depression and anxiety.Methods The acute stroke patients at our Neurology department and old-age cadres department were selected,in which have 88 cases of poststroke patients with depression and anxiety,which were divided into paroxetine group and the control group.Paroxetine group was given Seroxat 20 ng,1 time/d + conventional treatment of cerebrovascular disease.The control group was gaven conventional treatment of cerebrovascular disease only.After 4 weeks,6 weeks of treatment,we assessed Hamilton Depression Rating Scale(HAMD),Hamilton Anxiety Scale(HAMA),neurological deficit and the state of living ability were assessed.Results There were significant differences in improvenent of depression and anxiety,neurological deficit and the capacity of the state of life between the Paroxetine group and the control group the control group of 4 weeks treatment compared with before treatment(all P<0.05);Compared with before treatment,the control group of 6 weeks treatment compared with before treatment(all P<0.05);Paroxetine group of 4 weeks treatment compared with before treatment(all P<0.05);Paroxetine group of 6 weeks treatment compared with before treatment(all P<0.05),and Paroxetine group control is obvious Improved(all P<0.05).Conclusion Using Paroxetine to treat poststroke patients with depression and anxiety,not only could significantly improve symptoms of depression and anxiety,but also speed up the rehabilitation of limb function,efficacy reliable,and had no significant adverse reactions.So,it was an ideal medcine for poststroke patients with depression and anxiety.
2.Investigation on high-arsenic water:a report of 12 counties in Shaanxi Province in 2006
Chinese Journal of Endemiology 2008;27(3):303-304
Objective To explore the distribution of high-arsenic water in Shaanxi Province in order to provide theoretical basis for the control of arsenism.Methods The contents of arsenic of 4042 water sampled from 1898 nature villages in 12 counties were assessed using semi-quantitative reagent-knit,and the water samples of Shanyang County,the targeted area,was quantified using quantitative atomic fluorescent speemetry.Results The contents of arsenic of 6 water samples in 2 villages exceeded 0.05 mg/L,accounting for 0.15%(6/4042),were 0.46,0.53,0.63,0.69,0.74,1.53 mg/L,respestively,and located in Shanyang County.A crowd of 1146 exposed to hish asenic water.among whom 555 were children.Conclusions Arsenic in drink water in Shanyang County in Shaanxi Province is higher than the standard,to which a large number of people are exposed,water-improving and defluoridotion must be carried out as soon as possible,reduces harm of high arsenic.
3.An investigation on arsenide valence and speciation in urine of people in the endemic arsenism areas in the south of Shaanxi Province
Yue LI ; Guanglu BAI ; Aimei BAI ; Zhongxue FAN
Chinese Journal of Endemiology 2017;36(1):51-55
Objective To investigate the urinary arsenic levels of exposed population in various forms of and total arsenic (TAs) content as well as their relationship with arsenic poisoning in southern Shaanxi arsenic poisoning area.Methods According to the historical data of the investigation on arsenic poisoning,11 disease villages were chosen as survey sites in Ziyang and Pingli counties,Ankang city;three neighbor villages were chosen as control sites in Baihe.Baihe was a non-endemic arsenic poisoning area county,which had the same natural environment and living habits.In the survey sites,people over the age of 40 were selected for epidemiological investigation in both heating and non-heating seasons,and 40 urine samples were collected at each severity levels of the disease and in different seasons.Meantime,20 urine samples of the same age group were collected in the control sites in each season.Hydride generation-atomic fluorescence spectrometry (HG-AFS) was used to determine TAs,liquid chromatography-hydride generation-atomic fluorescence spectrometry (LC-HG-AFS) was used to determine the amount of inorganic trivalent arsenic (As3+),dimethylarsine (DMA),monomethylarsine (MMA) and inorganic pentavalent arsenic (AS5+),and the various forms and TAs were compared between different survey sites,severity levels,ages,sexes,and seasons.Results The medians of TAs,As3+,DMA,primary methylation index (PMI),and secondary methylation index (SMI) in diseased area (35.3,2.2,24.5 μg/L;0.84,0.90) were significantly higher than those of the control group (16.0,0.6,10.3 μg/L;0.78,0.81;Z =-9.069,-7.314,-8.913,-2.183,-3.853,P < 0.01 or < 0.05),and the medians of TAs,As3+,DMA,and SMI (31.6,2.0,23.1 μg/L;0.91) of the normal population in the diseased area were significantly higher than those of the control group (16.0,0.6,10.3 μg/L;0.81;Z =-7.164,-6.136,-7.023,-2.916,all P < 0.01).Illness had positive correlations with TAs,DMA,and ages (r =0.370,0.367,0.594,all P < 0.01).Men arsenic poisoning detection rate,TAs,As3+,and DMA (59.9%,37.4,2.5,25.2 μg/L) were significantly higher than those of women (22.4%,30.0,1.6,20.9 μg/L;x2 =54.878,P < 0.01;Z =-3.332,-4.449,-2.681,all P < 0.01).The medians of As3+,MMA,As5+,PMI,and SMI in the heating season (1.5,2.1,1.4 μg/L;0.87,0.92) were significantly different from those in the non-heating season (2.6,3.3,3.0 μg/L;0.82,0.88;Z =-6.870,-5.512,-8.542,-2.262,-4.544,P < 0.01 or < 0.05).Conclusions The TAs,As3+,and DMA of urine samples are related to local arsenic background,so they have some reference value for determination of diseased areas.Men are more susceptible to arsenic poisoning than women.
4.Effects of stellate ganglion block on the pain and quality of life in patients with lung cancer
Lijun BAI ; Xiaoyan LIU ; Limin YUE
Chinese Journal of Primary Medicine and Pharmacy 2017;24(8):1140-1143
Objective To investigate the effect of stellate ganglion block on the pain and quality of life in patients with lung cancer.Methods 90 patients with lung cancer were divided into observation group and control group according to random number table method.The control group was treated with morphine 10mg,orally,1 time/ 12h.The observation group was treated with stellate ganglion block and morphine.For the patients with poor analgesic effect,50% doses were added gradually.The analgesic effect,quality of life and changes of immune function were compared between the two groups.Results After treatment,the VAS scores of the two groups were significantly decreased.And the VAS score reduction in the observation group was significantly better than that in the control group [(2.5 ± 0.7) points vs.(3.7 ± 0.9) points],the difference was statistically significant (t =7.060,P < 0.05).The analgesic efficacy of the observation group was significantly higher than that of the control group(91.1% vs.75.6%,x2 =3.920,P < 0.05),the duration of analgesia of the observation group was longer than that of the control group (t =20.681,P < 0.05).For the total morphine dosage method,the observation group was significantly lower than the control group[(143.5 ± 21.3) mg vs.(238.7 ± 38.3) mg] (t =14.572,P < 0.05).After treatment,the scores of quality of life of the two groups were significantly improved,and the improvement degree of the observation group was significantly better than that of the control group [(86.5 ± 14.3) vs.(79.6 ± 15.7),t =2.179,P < 0.05].After treatment,the TGF-beta level of the observation group was significantly reduced,which was significantly lower than that of the control group[(215.4 ± 38.7)pg/mL vs.(240.5 ± 41.2)pg/mL],the difference was statistically signifi cant (t =2.979,P < 0.05).Conclusion Stellate ganglion block has good therapeutic effect in the treatment of lung cancer patients with pain.
5.Hygienic Survey of Drinking Water Plants in Shanxi Province
Linkai BAI ; Yijiao DU ; Tao YUE
Journal of Environment and Health 1993;0(01):-
Objective To know the hygienic condition of different kinds of drinking water plants in Shanxi Province.Methods In 2007,422 water plants and 2 083 secondary water supply units were selected and the information and data that provided by all Sanitation Institute for Health Inspection and Supervision in Shanxi Province were analyzed.Results The hygienic conditions of city's municipal administration water supply systems were the best.Total qualified rate of water quality was 97.67%.The hygienic conditions of rural school's homemade water supply systems were the worst,the qualified rates of all items in the program were the lowest.Most of them had no any analyst and laboratory for water quality test.Only 10.2% of them had water disinfection facilities.Total qualified rate of water quality was 75.32%.In most of water plants,the lack of water quality test facilities and disinfection facilities was one important problem in drinking water safety.In addition,the lack of clean and disinfection in secondary water supply systems was another problem.Conclusion The hygienic conditions of drinking water plans are unsatisfactory and should be improved in Shanxi Province.
6.The Survey of Arsenic and Fluoride Levels in Coal from Coal Mines in South of Shaanxi
Yue LI ; Aimei BAI ; Changan MA
Journal of Environment and Health 2007;0(11):-
Objective Identify the arsenic and fluorin contents in coal from major producing coal mines in south of Shaanxi,providing a scientific foundation for the formulation of the prevention strategy.Methods In the 6 major coal mine areas governed by Ankang and Hanzhong city,the 62 mines with comparatively large production scales and sales locally,which may have some effective forces on the causing of the local arsenic and fluorin poisoning,were inveatigated,on-the-spot sampling are carried out,the fluorine in coal was determined by the combustion-hydrolysis/fluoride-ion selective electrode method and the arsenic in coal was determined by the atomic fluorescence.Results The maximum of the fluoride content in coal from the 62 investigated coal mines was 3 053.04 mg/kg,and the minimum was 6.58 mg/kg;the arithmetic mean was 1 034.30 mg/kg;the geometric mean was 656.85 mg/kg;The maximum of arsenic content in coal was 484.71mg/kg,and the minimum was 29.64 mg/kg;the arithmetic mean was 197.64 mg/kg,the geometric mean was 174.29 mg/kg.Conclusion The contents of fluoride and arsenic are seriously exceeded the standard limits in the 62 investigated coal mines,especially in stone coal mines.
7.Analyses on Non-Technical Medical Factors in the Physician-Patient Conflict
Ning BAI ; Changhong YUE ; Zhonghua LI
Chinese Medical Ethics 1996;0(01):-
Relations between doctors and patients are the most basic and important human relations in medical practice.Some reports indicate that non-technical medical factors result in most cases of physician-patient conflicts.In this paper we analyzed non-technical medical factors from the fields of society,ethics and mentality,and concluded main reasons for physician-patient conflicts are the lack of "being discreet when alone",the absence of "patients-oriented service concept",the ignorance of responsibility of "life-saving",and the missing of humanity care.
8.Endoscopic mucosal resections and follow-up study for 8 patients with colonic laterally spreading tumors with early carcinomatous change
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
Objective To eraluate the methods and results of endoscopic mucosal resections for colonic laterally spreading tumors with early malignant degeneration. Methods The pit pattern was studied with magnitying colonoscopy and mucosal staining technique for colonic laterally spreading tumors (LST) undergoing early earcinatous degeneration. They were removed with endoscopic mucosal resection techniques. A follow-up study was made. Results Eight patients suffering from early carcinoma on top of colonic laterally spreading tumors were followed-up. ① 75% of the lesions were situated in the rectum, sigmoid colon and decending colon. ② 75% of the lesions were larger than 30mm in diameter. ③ 75% of the lesions belonged to Ⅳpit pattern. ④ 62.5% of the lesions were Villous adenomas and 75% of the onalignant change involved the mucosa only. ⑤ All the lesions were completely removed by EMR, ⑥ No local residual lesion, recurrence or metastasis was discovered in all the patients after a mean follow-up period of 20.7 months. Conclusions Most of the early carcinomas originated from colonic LST involved the mucosa only. Endoscopic mucosal resection may be a curative method for the early cancer arising from colonic LST.
9.Survey and intervention into rural doctors' knowledge on the spread of HIV via blood collection and supply
Chinese Journal of Hospital Administration 1996;0(10):-
Objective To find out about rural doctors' knowledge on the basic facts about AIDS and the spread of HIV via illegal blood collection and supply and explore viable intervention methods in AIDS prevention and treatment in rural areas. Methods All the rural doctors in a certain township where the epidemic of HTV being spread via blood collection and supply was pretty serious were selected for the survey and data were collected by combining qualitative and quantitative studies. Results The survey of 33 doctors was effective( 100% ) ; above 95% had a correct understanding of the spread of AIDS through sex and blood as well as its contagiousness; 50% did not possess the knowledge that HIV could be spread to the baby by the mother but could not be spread through saliva, sweat, mosquito bites or sharing of bathtubs or toilets; above 80% knew about the objective of the blood organizers in their villages, the peak time of blood selling by the villagers, and the risks of diseases being spread via blood, and were opposed to blood selling; 27.3% once in a while used disposable syringes, and 15.2% discarded or sold used disposable syringes. Conclusion There are severe lurking perils of iatrogenic cross infection in rural areas. Rural doctors are in dire need of formal training in AIDS prevention and treatment knowledge and could be expected to become the key force in AIDS prevention and treatment in rural areas.
10.Analysis on the Present Situation and the Restricting Factors of Relique Donation in China
Ning BAI ; Fuchuan SUN ; Changhong YUE
Chinese Medical Ethics 1995;0(04):-
Donation of relique is important to not only medicine development,but the social civilization also.But the development of it is late and laggard in China.According to investigation and analysis in some regions,we find several factors restricting the donation of relique such as the obstacle of morals,the lag of legislation,lack of the humanistic care.These are the keys for us to change the behindhand situation of relique donation in China.