1.Infective Endocarditis and Chronic Kidney Disease: How to Deal with Complications
Yusra Habib Khan ; Azmi Sarriff ; Amer Hayat Khan ; Azreen Syazril Adnan ; Tauqeer Hussain Mallhi
Malaysian Journal of Medical Sciences 2015;22(4):73-75
Infective endocarditis (IE) is the one of the most important causes of increased mortality and morbidity among haemodialysis patients. The reason for this increasing prevalence of infection among these patients is the use of haemodialysis catheters during dialysis, as these patients are highly susceptible to infections that are easily transmitted via blood access points.
The present case was a geriatric end stage renal disease (ESRD) patient who was readmitted to the hospital two days after her scheduled haemodialysis session with symptoms of nosocomial endocarditis. Her concurrent medical complications were hypertension, non-insulin dependent diabetes mellitus, and ischemic heart disease. Based on her previous medical history and current examination, the patient was suspected to have IE due to catheter related infection.
The goal of therapy is to manage the comorbidities and infection by provision of appropriate treatment based on close monitoring of the patient condition.
2.Periodontal Health of Pre-Dialysis Chronic Kidney Disease Patients in a Northeast Peninsular Malaysia Tertiary Hospital
Hanim Afzan Ibrahim ; Nur Karyatee Kassim ; Fatimah Zahra Jamsari ; Siti Lailatul Akmar Zainuddin ; Muhammad Hafiz Hanafi ; Azreen Syazril Adnan
Malaysian Journal of Medical Sciences 2020;27(1):106-114
Introduction: Chronic kidney disease (CKD) is associated with periodontal disease due to
its hyperinflammatory state. Limited studies have explored the prevalence of periodontal disease
among CKD patients in Malaysia.
Objective: To assess the periodontal status of pre-dialysis CKD patients in Hospital
Universiti Sains Malaysia.
Methods: A total of 46 pre-dialysis CKD patients who attended the nephrology clinic
at Hospital Universiti Sains Malaysia were enrolled in this study. Periodontal examination was
performed using the periodontal probing depth (PPD), clinical attachment loss (CAL) and plaque
index.
Results: The majority of the CKD patients were Malay (95.7%) and 80.4% were males.
The mean age of the patients was 58.5 years. Using PPD measurement, 37 (74.0%) of the patients
had mild periodontitis, 9 (20.0%) had moderate periodontitis and 3 (6.0%) had no periodontitis.
Based on CAL measurement, 12 (26%) patients had mild periodontitis, 29 (63.0%) had moderate
periodontitis and 5 (11%) had severe periodontitis. The mean (standard deviation [SD]) value
of mild and moderate-to-severe periodontitis by PPD measurement were 4.26 (0.26) and 5.24
(0.36), respectively. The mean of mild and moderate-to-severe periodontitis by CAL measurement
were 2.66 (0.62) and 4.98 (0.73), respectively. There was no correlation between the periodontal
parameters and estimated glomerular filtration rate (PPD: r = −0.160, P = 0.914; CAL: r = −0.135,
P = 0.372; plaque index: r = 0.005, P = 0.974).
Conclusion: This study revealed a greater prevalence and severity of chronic periodontitis
among CKD patients. Thus, the periodontal health of CKD patients’ needs to be screened and
monitored.