To implant a drain tube or stent into bile tract during operation plays an important role in biliary surgery. In recent years, a variety of biomaterials have been employed in this procedure and scored manifold results in biological basic research. The progresses in nonmetallic biomaterials mainly included exploring the image compatibility of silicone itself, investigating bilolgical effects of silastic surface chemical modification, and preparing new bioabsorbable biliary stents. The focus of studyies on metallic ones was on the biocompatibility evaluations of cytotoxicity, genotoxicity and histo to xicity of nickel, titanium and Ni-Ti alloy, as well as the influence of on biocompatibility and hemocompatibility of Ni-Ti shape memory surgical alloy.