1.A trial of Oral Glucocorticoids in the resolution of recurrent Granulomatous Hypophysitis: A case report
Katrina Rodriguez-Asuncion ; Thelma Crisostomo
Journal of the ASEAN Federation of Endocrine Societies 2019;34(2):210-214
Granulomatous hypophysitis is an extremely rare condition, with no established definitive treatment. An elderly Asian woman was diagnosed to have recurrent granulomatous hypophysitis 5 years after transsphenoidal surgery. No other intervention was done post-operatively. Since another surgery was not advisable due to the high probability of recurrence, she was started on a trial of oral glucocorticoids. After 3 months of steroid therapy, complete resolution of symptoms and sellar mass were achieved.
Autoimmune Hypophysitis
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Glucocorticoids
2.Primary hypoparathyroidism and non-functioning pituitary adenoma: An incidental coexistence?
Journal of the ASEAN Federation of Endocrine Societies 2014;29(1):86-89
Primary hypoparathyroidism is caused by a group of heterogeneous conditions in which hypocalcemia and hyperphosphatemia occur as a result of deficient parathyroid hormone (PTH) secretion. The most common cause is surgical excision and damage to the parathyroid gland(s). Nonetheless, autoimmune endocrine disorder of primary hypothyroidism has been well-described in polyglandular autoimmune syndromes (PAS).1 Its association with pituitary lesion may be autoimmune lymphocytic hypophysitis as the cause for pituitary disorder. In this report, we encountered a patient with primary hypoparathyroidism who had a non-functioning pituitary tumour. It was confirmed as pituitary adenoma rather than lymphocytic hypophysitis from the histopathological examination. To our knowledge, this is the first reported case of non-functioning pituitary macroadenoma and primary hypoparathyroidism.
Hypopituitarism
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Autoimmune Hypophysitis
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DiGeorge Syndrome
3.Idiopathic Granulomatous Hypophysitis with Rapid Onset: A Case Report
Hyun Joo PARK ; Sung Hye PARK ; Jung Hee KIM ; Yong Hwy KIM
Brain Tumor Research and Treatment 2019;7(1):57-61
Idiopathic granulomatous hypophysitis (IGH), a rare disease, requires differentiation from more common mass lesions of the sella such as pituitary adenoma, craniopharyngioma, Rathke's cleft cyst, or pituitary tuberculoma. IGH usually presents with an insidious onset of visual defects and headaches. On the other hand, rapid onset of neurologic and visual symptoms in an IGH patient is exceptionally rare. Here, we present a biopsy-proven case of IGH with rapid onset and satisfactory outcome after high dose steroid treatment.
Adult
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Autoimmune Hypophysitis
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Craniopharyngioma
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Endoscopy
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Glucocorticoids
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Hand
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Headache
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Humans
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Pituitary Gland
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Pituitary Neoplasms
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Rare Diseases
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Sella Turcica
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Tuberculoma