1.Effect of aspirin on erythrocyte aggregation.
Journal of Practical Medicine 2002;435(11):10-11
33 patients who were definitely diagnosed with acute myocardial infarction (MI) using WHO criteria were involved in this study. Statistic method of STARTA 95 was used to compare erythrocyte aggregation after and before using aspirin. Aggregation of erythrocyte increased in the acute stage of MI. Oral aspirin with dose of 0.1g per day for 3 days reduced significantly the erythrocyte aggregation in MI patients, compared with baseline.
Aspirin
;
Erythrocyte Aggregation
2.Study on pilot manufacture of aspirine microgelules
Pharmaceutical Journal 2005;0(5):20-24
Announcement of some initial results of making and investigating some particularizes of aspirin microfollicle. Percentage of asprin between theory and reality has remarkable change (+16.57 to -1.37). In generally, the microcapsules sample have low rate of Asp/EC, the aspirin microencapsulated rate is high and vice versa. Parameters of asparin percentage, rate of Asp/EC influence on asparin microencapsulated rate. Asparin capsule with EC box can be made with relatively high microencapsulated rate productivity. Aspirin capsule can last liberation of pharmaceutical material and give long-lasting effect in systems
Aspirin
;
Pharmaceutical Preparations
3.Prevalence and Clinical Characteristics of Aspirin Resistance in the Patients with Type 2 Diabetes.
Korean Diabetes Journal 2008;32(2):171-172
No abstract available.
Aspirin
;
Humans
;
Prevalence
5.Dose Aspirin Inhibit the Expression of Nuclear beta-Catenin In Vivo As It Does In Vitro Studies?.
Intestinal Research 2013;11(4):236-237
No abstract available.
Aspirin*
;
beta Catenin*
6.Electron Microscopic Study of the Renal Proximal and Distal Convuluted Tubular Epithelial and Distal Convoluted Tubular Epithelial Cells after Administration of Aspirin.
Sung Gum HONG ; Cheul Woon BACK ; Im Ju KANG ; Byung Heon KIM ; Dong Koo LEE
Journal of the Korean Pediatric Society 1983;26(6):564-572
No abstract available.
Aspirin*
;
Epithelial Cells*
7.The Effect of Aspirin on Survival in Patients with Mutated-PIK3CA Colorectal Cancers.
Intestinal Research 2013;11(1):71-72
No abstract available.
Aspirin
;
Colorectal Neoplasms
;
Humans
8.Aspirin Resistance in Patients Undergoing Dialysis.
Korean Journal of Nephrology 2011;30(2):131-133
9.Association of long-term oral low-dose aspirin and survival in colorectal cancer: a meta-analysis.
Hua YE ; Ping CHEN ; Wenyu DAI ; Qi ZHENG ; Feng WU
Chinese Journal of Gastrointestinal Surgery 2015;18(6):589-592
OBJECTIVETo examine the association between long-term oral low-dose aspirin and overall survival in colorectal cancer patients after diagnosis.
METHODSThe literature databases, such as PubMed, Embase, Cochrane Library, Web of Science, CBM, CNKI, and Wanfang database, were extensively searched to retrieve the comparative studies about the association between low-dose aspirin use after colorectal cancer diagnosis and overall survival published before June 2014. The state 12.0 version software was used for meta-analysis. The quality of these studies was assessed using the Newcastle-Ottawa scale.
RESULTSThere were eight studies meeting the inclusion criteria for meta-analysis. The total sample size of these studies included 28 103 cases and the score of all the studies was more than 6 points. Meta-analysis of the data using I(2) test showed significant heterogeneity (I(2)=78.2%, P<0.01), therefore, a random effect model was performed. Aspirin use after diagnosis was associated with longer overall survival (HR=0.732, 95% CI:0.613-0.875, P<0.01). There were seven studies with the same design or tumor stage in I-IIII period respectively for sensitivity analysis. The results of studies showed that the sensitivity was low and accurate (HR=0.687, 95% CI: 0.557-0.849, P<0.01; HR=0.682, 95% CI: 0.539-0.864, P<0.01).
CONCLUSIONMeta-analysis shows that long-term oral low-dose aspirin after diagnosis of colorectal cancer is identified as a significant prognostic factor.
Aspirin ; Colorectal Neoplasms ; Humans
10.Cost-effectiveness analysis of first trimester screening for preeclampsia and early initiation of aspirin therapy for prevention of the disease in a private tertiary hospital
Carol Joanna G. Violago ; Irene B. Quinio
Philippine Journal of Obstetrics and Gynecology 2021;45(2):47-54
Background:
Preeclampsia (PE) has significant health and economic burden. Early screening for PE through first trimester screening (FTS) can direct decision-making on early initiation of aspirin (ASA) therapy, which has been known to reduce the incidence of PE.
Objectives:
The objective of the study is to evaluate the cost-effectiveness of FTS and early initiation of ASA for disease prevention.
Methodology:
A population of 1916 women who delivered in a private tertiary hospital from January 2019 to March 2020 was categorized based on the risk of developing PE, results of FTS, initiation of ASA therapy, development of PE, and mode of delivery. Descriptive statistics using counts and percentages were used to summarize the data. Association between ASA therapy and PE was assessed using the Chi-square test. Costs of screening, ASA therapy, inpatient management, and delivery were computed.
Results and Conclusion
Results showed that PE was prevented in 71.4% of those high-risk patients who underwent FTS and started on ASA therapy. Total cost of urgent care of PE and delivery was P119,687.02 to P149,687.02 for early PE, and P103,587.02 to P133,587.02 for late PE. Prevention of early PE and late PE results in net cost savings of P69,694.02 and P53,594.02, respectively, with the investment of P9,993.00 on FTS and ASA therapy. Implementation of FTS and initiation ASA therapy is an effective and cost-saving approach that can prevent PE.
Aspirin
;
Pre-Eclampsia