Changes of cardiac structure and action in elderly led to the arrhythmia such as extrasystole (symptoms, treatment and prognosis), arterial fibrillation (anticoagulation for reduction of the risk of cardiovascular accidents, reduction of ventricular rhythm, normalization of sinal rhythm), sick sinal syndrome and transmission disorders were studied.
Arrhythmia ; aged

Since 1975, lidocaine has been made up in Friendship hospital with the name rythmocardyl as a dissoluble tablet in the bowels. The magistral formula and processing procedures have been studied and tested to reach the VNP II - 1994 and BP-1993 standards. The lethal dosage (LD50), the anti - ventricular fibrillation and anti-arrhythmic effects, the blood concentration of lidocaine taken orally at different times as well as the dissolution of rythmocardyl in the human body have been tested experimentally. The research have proven that lidocaine, taken orally has few side effects and is safe and effective to treat the cardiac arrhythmia, notably the ventricular extrasystoles
Lidocaine ; Arrhythmia ; tablets ; therapeutics

Among 112 patients after myocardial infarction (MI), males account for 94.6% with mean age is 66.47.4 years old. Most of them have complicated ventricular arrhythmia. The grade IV and V of ventricular arrhythmia on Lown classification relate strongly to the increase in left ventricular diameter, volume, weight and muscular mass and to the decrease in left ventricular systolic function. Increasing in left ventricular size (Dd 52mm, Ds 35mm, EDV 125ml, ESV 50ml), left ventricular hypertrophy (LVMI = 130g/m2), decreasing in blood ejective fraction (EF=40%) and ventricular wall distension all increase the risk of complicated and ventricular arrhythmia and grade III, IV and V of this condition according to Lown classification
Myocardial Infarction ; Arrhythmia ; ultrasonography

The signal averaged electrocardiogram was used to analyse about 100 to 300 heart leads. Then the high resolution electrocardiograms were processed to identify the low intensive high-frequency electric signals at the end of QRS complexes that expressed the late potential and were the background of ventricular arrhythmias. There was a strong relationship between the arrythmias that were triggered by programmed physiological electric stimulations and the presence of late potential. The late potential also related to the increase in sudden death frequency of post MI patients. It is a value predictor for arrythmic events
Myocardial Infarction ; Arrhythmia

8 patients (male/female: 1) with ages of 18-63 diagnosed as arrhythmias but not classify the type of arrhythmias who received the transesophageal electrocardiogram. The results have shown that the transesophageal electrocardiogram increased the umplitude and displayed clearly the atriogram which help determined diagnosing, especially differentially diagnosing the ventricular and supraventricular tachycardiac. This was a simple technique that can be applied in the local levels to diagnose some arrhythmias
Echocardiography, Transesophageal ; Electrocardiography ; Arrhythmia ; diagnosis

Propafenone (Rythmonorm) was administered intravenously at a dose of 5mg/kg/3h to treat an atrial fibrillation case. Synal rhythm was restored in 2.30 hours with a QRS complex enlargement. 3 hours later on, a blood pressure drop as well as a cerebral and myocardial ischemia lasting 2 days were noted and were managed effectively with isoproterenol and dopamine. These drugs administered orally in divided doses up to 450 mg/day can put an end to the atrial fibrillation paroxysm while the maintenance dose of 450mg/day in fractional doses can prevent atrial fibrillation recurrence
Anti-Arrhythmia Agents ; Propafenone ; Overdose ; Accidents

40 hypertension patients aged from 45-75 years, with the signs of thickening of left heart ventricle detected by radiography, ECG and ultrasound were enrolled in tis study. The control group includes 35 other patients with the same range of age and the same stage of hypertension without thickening of left heart ventricle. The authors didn’t find any relation between the thickening of left heart ventricle and arrhythmia.
Hypertension ; Arrhythmia ; Antihypertensive Agents ; Electrocardiography ; Radiography ; Ultrasonography

Diabetic polyneuropathy affects millions of people with diabetes. Although, the symptoms may be highly unpleasant, management have concentrated mainly on the disease process and other more visible or devastating secondary complications like diabetic ulcers and cardiac arrhythmia. Glycemic control remains the most important aspect in the management of diabetes that can deter or decelerate subsequent development of diabetic polyneuropathy. However, concentration on this aspect alone veers away from control of symptoms that may improve quality of life of patients.
NEUROPATHY ; CARDIAC ARRHYTHMIA ; PAIN ; INJURY ; NERVE

BACKGROUND/AIMS: Long-term antiarrhythmic drug therapy remains the principal approach for suppressing atrial fibrillation (AF) and maintaining sinus rhythm. In this study, we examined the differing electrophysiological effects of various antiarrhythmic drugs on the cardiac chamber and atrial selectivity in patients with AF. METHODS: We analyzed 134 patients (60.4 +/- 12.5 years, M:F = 1.14:1) who were administered a single antiarrhythmic agent for AF over 6 months: amiodarone (group A), flecainide (group F), or propafenone (group P). The P wave, QRS complex duration and dispersion, and QT interval and its dispersion were evaluated using a standard 12-lead electrocardiogram. RESULTS: There was no significant difference in age, gender ratio, or associated diseases among the three groups. In group A, Pmax, Pmin, P dispersion, QRSmax, QRSmin, and QRS dispersion were shorter than in groups F and P, whereas Pmax/QRSmax was the highest in group A (A = 1.2, F = 0.9, P = 1.0; p < 0.01). QTcmax and QTcmin were longer in group A, whereas QTc dispersion and the QT peak to end (A = 13.3 +/- 11.2, F = 30.7 +/- 24.9, P = 31.8 +/- 21.6; p < 0.01) were shorter in group A than in the other groups. CONCLUSIONS: Amiodarone had a weaker, but more selective, inhibitory effect on intra-atrial conduction, and inhibited ventricular repolarization more effectively and homogenously than flecainide or propafenone. These differing electrophysiological effects may contribute to the superior effectiveness and safety of amiodarone over flecainide or propafenone.
Amiodarone ; Anti-Arrhythmia Agents ; Atrial Fibrillation ; Electrophysiology ; Flecainide ; Humans ; Propafenone

Anti-Arrhythmia Agents ; therapeutic use ; Atrial Fibrillation ; drug therapy ; Humans