INTRODUCTION: In the modern medical practice of Mongolia, autoimmune diseases have notbeen diagnosed in its early stage. The autoantibodies are useful in the patient’s early diagnosis,prognosing, and treatment of autoimmune diseases.GOAL: The aim of the study was to compare the prevalence and levels of autoantibodies in theserum of patients with autoimmune diseases.MATERIALS AND METHODS: This patient-based descriptive study involved 144 participants, withconfirmed diagnosis of autoimmune disease and glomerulonephritis (GN). Face to face interviewwas used to obtain necessary information followed by the physical examination and autoantibodies(anti-SS-A/Ro, anti-SS-B/La, anti-SCL-70, c/p-ANCA, anti-GBM, anti-Sm) measured by Enzyme-Linked Immunosorbent Assay (ELISA).RESULTS: The prevalence of anti-SS-A/Ro 38.6%, anti-Sm 25.7%, anti-SS-B/La 8.6%, c-ANCA7.14%, anti-SCL-70 1.4% were positive in autoimmune disease group (secondary GN), theprevalence of anti-SS-A/Ro 6.8%, anti-Sm 2.7%, anti-SS-B/La 2.7%, c-ANCA 1.4% were positivein primary GN group. A higher frequency of anti-SS-A/Ro 66.4%, anti-SS-B/La 22.8%, and anti-Sm38.4% was observed in the SLE group.CONCLUSIONS: Patients with autoimmune disease was significantly higherly younger and female.SLE associated with several auto antibodies (anti-SS-A/Ro, anti-SS-B/La, and anti-Sm) and eachof which are very useful in distinguishing patients with SLE from other autoimmune diseases.

BACKGROUND: Microtia is often associated with hearing loss and patients typically require treatment for hearing impairment and surgical ear reconstruction. The occurrence of microtia is of public health importance in part due to the psychosocial sequelae, including the stigma associated with malformations of the ear and the burden of undergoing multiple surgeries In addition, greater than 90% of individuals with microtia experience conductive hearing loss on the affected side. Although children with microtia-anotia are at a greater risk of delayed language development and attention deficit disorders. METHODS: Our study has a 173 childrens from the UB city and countryside. 23 children has a bilateral microtia and anotia. 6 patient wearing BAHA soft band from 6 months age. 150 patients have an unilateral microtia. Microtia was found more commonly in males, unilateral and right sided. Even children with bilateral microtia may have wearing BAHA soft band before 6 months age. RESULTS: External ear malformations are more commonly found in males. Sex ratio 2:1. From other studies right ear malformations are more common in male children. In our study children who have bilateral ear abnormalities wearing BAHA softband and language therapy from 6 months age to able to have normal language development. Children who had surgical treatment and using hearing aid can have normal social life and increased quality of life. CONCLUSION: Early screening in children who have external ear malformation, monitoring language development, wearing BAHA softband from 2 months age who have bilateral ear malformation and one ear affected other one is normal children wear BAHA softband increases children speech and language development.

BACKGROUND. Over 5% of the world’s population or 466 million people have disabling hearing loss (432 million adults and 34 million children). Profound sensorineural hearing loss and deafness can be treated successfully with a cochlear implant. A cochlear implant (CI) stimulates the auditory nerve, bypassing the defective cochlea, and provides auditory information to the developing brain, thus improving oral language. Children, who receive an early diagnosis of deafness and proper speech rehabilitation, and undergo early cochlear implantation, are able to develop auditory and linguistic skills at par with their hearing peers. METHOD. 6 deaf patients who underwent unilateral Cochlear Implantation at the NCMCH from January 2017 to June 2018 were included in the study. Participants were divided into 3 groups on the basis of age at which participants underwent implantation. RESULTS. Pre-op average MAIS was 1,6/40, Category of Auditory Performance (CAP) - 0,77 and SIR - 0,7/5 in all implanted age groups. Score increased over time to attain average score MAIS -29.6/40, CAP- 3.3/7 SIR-2.7/5 in all implanted groups at one year after implantation. CONCLUSION. There is a need for more research on patient age and gender composition, and outcomes of cochlear implantation and hearing devices in this study population. A robust set of study measures would provide statistical significance. Parent-child relationships affect hearing and speech therapy results, so there’s a need to improve parents’ knowledge regarding these therapies.