1.Pure Red Cell Aplasia Following Thymothymectomy: A Case Report
Anuradha Ck Rao ; Bhavna Nayal ; Chethan Manohar
Malaysian Journal of Medical Sciences 2013;20(5):83-85
Thymoma, a rare epithelial neoplasm, is the most common anterior-superior mediastinal tumour. Thymoma can occur sporadically or in association with other conditions, such as myasthenia gravis, pure red cell aplasia (PRCA), and hypogammaglobulinemia. Only 5% of thymoma cases develop PRCA; however, 10–50% of patients presenting with PRCA have an associated spindle cell type thymoma. Thymoma complicated by PRCA is associated with a poor outcome. We report the case of a 38-year-old female who presented with chest pain, and was diagnosed with an anterior mediastinal mass. A thymectomy was performed, and histopathological examination revealed mixed thymoma; two months later, the patient developed PRCA. The present case reinforces the need for clinicians to be vigilant with thymoma patients, even following thymectomy.
Erythropoiesis
;
Mediastinum
;
Red-Cell Aplasia, Pure
;
Thymoma
2.Rare Presentation of Pseudomyxoma Retroperitonei: Stretching the Limits
Roumina Hasan ; Sandeep Kumar ; Anuradha ck Rao ; Rajagopal Kadavigere
Malaysian Journal of Medical Sciences 2016;23(4):79-85
A 55-year-old woman presented with a mucopurulent sinusal discharge from the right
supragluteal region, with symptoms over the previous five months. This abscess began as a slowly
swelling growth, which eventually turned into a discharging sinus, and she was diagnosed with a
gluteal abscess. The patient underwent incisional drainage, and intra-operatively, the sinus tract could
be seen extending to the retroperitoneum. A subsequent CT scan and an MRI of the abdomen revealed
a large heterogeneous retroperitoneal cystic mass on the right side of midline, extending inferiorly
into the anterior thigh along the iliopsoas. Superiorly, a tubular projection extended from the lesion,
indenting the ileocaecal junction, while a fluid filled cutaneous fistulous tract was seen, extending
to the right flank. A diagnosis of pseudomyxoma retroperitonei, likely of retrocaecal appendicular
origin, was proposed. An explorative laparotomy with an appendectomy, and the evacuation of the
retroperitoneal collection were completed. The subsequent histopathology confirmed the diagnosis
of appendicular mucinous cystadenoma, with pseudomyxoma retroperitonei.