1.In vitro susceptibility of bacterial conjunctivitis standard isolates to non-fluoroquinolone ophthalmic medications
Moses Job D. Dumapig ; Eric Constantine Valera
Health Sciences Journal 2021;10(1):25-34
INTRODUCTION:
This study aimed to determine the in vitro susceptibility of standard isolates of common pathogens causing bacterial conjunctivitis to non-fluoroquinolone antimicrobial ophthalmic medications.
METHODS:
This is a single-blind experimental study which compared the in vitro susceptibility of Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa and Staphylococcus epidermidis to locally available non-fluoroquinolone ophthalmic medications, specifically chloramphenicol, tobramycin, fusidic acid, gentamicin sulfate, sulfacetamide and polymyxin-neomycin. Utilizing the disk diffusion method, zones of inhibition in millimeters for each bacterial isolate was recorded and tabulated. Kruskal-Wallis test was used to determine statistical differences.
RESULTS:
Both Staphylococci were sensitive to all antibiotics except sulfacetamide. Only chloramphenicol showed activity against all four isolates. Tobramycin showed the largest zone of inhibition against Pseudomonas aeruginosa. There was statistically significant difference in the median zone of inhibition in each antimicrobial medication against Staphylococcus aureus (p = 0.002) and Staphylococcus epidermidis (p < 0.001) with the largest mean zone of inhibition by fusidic acid of 34 and 38 millimeters, respectively. Streptococcus pneumoniae was least susceptible to antibiotics tested; only chloramphenicol and fusidic acid showed activity. There were also significant differences in the median zones of inhibition across the isolates.
CONCLUSION
The standard isolates are susceptible to at least one non-fluoroquinolone ophthalmic medication. The antibiotics tested showed differences in activity against the four isolates. The findings of this study may be used as a basis to review local practice patterns or/and initiate revisions in the guidelines for prescribing initial treatment of bacterial conjunctivitis.
Conjunctivitis, Bacterial
;
Anti-Bacterial Agents
2.Investigation of lactic acid bacteria’s abilities of transfering the anti-antibiotic gene by conjugation
Journal Ho Chi Minh Medical 2005;9(1):35-38
Isolate, purify, and identify bacteria from probiotic supplement. Results: 5 strains of lactic bacteria were determined, including: Steptococus feacalis; Streptococcus lactic; Bifidobacterium bifidum; Lactobaccillus acidophilus; Lactobacillus casei. Study the sensitivity of these bacteria with antibiotics, results showed that these bacteria were resistant to many antibiotics, especially oral antibiotics. Conjugative trial between Streptoccocus feacalis, Streptococus lactic, Bifidobacterium bifidum, lactobacillus acidophilus casei and E.coli K12, and conjugative trial of lactic bacteria together showed negative results. Therefore, probiotic product contained many lactic bacteria can be used concomitant with some oral antibiotics to prevent or treat digestive disorders
Anti-Bacterial Agents
;
Bacteria
3.Oral antibiotics.
Journal of the Korean Academy of Family Medicine 1998;19(10):757-765
No abstract available.
Anti-Bacterial Agents*
4.Effectiveness of Immediate Antibiotics Treatment after Provoking Intrauterine Infection in Pregnant Rabbit.
Gil Sang EUN ; Kyo Hoon PARK ; Bo Hyun YOON ; Am KIM ; Jin Yong LEE
Korean Journal of Obstetrics and Gynecology 1997;40(12):2780-2792
No abstract available.
Anti-Bacterial Agents*
5.Efficacy of Preoperative Topical Fluoroquinolone Antibiotics in Intraocular Surgery.
Journal of the Korean Ophthalmological Society 2012;53(5):740-741
No abstract available.
Anti-Bacterial Agents
6.Predictive factors and initial selection of antibiotics in neonatal sepsis.
Dong Chul PARK ; Chul LEE ; Kook In PARK ; Ran NAMGUNG ; Dong Gwan HAN
Journal of the Korean Pediatric Society 1991;34(6):755-762
No abstract available.
Anti-Bacterial Agents*
;
Sepsis*
7.The effects of antibiotics on phagocytosis and bacterial morphology.
Duk Han KIM ; Mi Gyeong KIM ; Min Jung KIM ; So Gyem YOON ; Yung Bu KIM ; Yang Hyo OH
Journal of the Korean Society for Microbiology 1993;28(3):183-192
No abstract available.
Anti-Bacterial Agents*
;
Phagocytosis*
8.Target Controlled Infusion.
Journal of the Korean Medical Association 2003;46(5):454-460
Target controlled infusion(TCI) is an infusion system which allows the anesthetist to select the target blood concentration required for a particular effect and then to control the depth of anaesthesia by adjusting the requested target concentration, which includes the instantaneous calculation of the infusion rate necessary to obtain and maintain a given therapeutic blood concentration of drug based on average pharmacokinetic parameters. We can apply this concept of infusion system not only to anesthetics but also to any kinds of intravenous drug infusion including antibiotics in the future.
Anesthetics
;
Anti-Bacterial Agents
9.Target Controlled Infusion.
Journal of the Korean Medical Association 2003;46(5):454-460
Target controlled infusion(TCI) is an infusion system which allows the anesthetist to select the target blood concentration required for a particular effect and then to control the depth of anaesthesia by adjusting the requested target concentration, which includes the instantaneous calculation of the infusion rate necessary to obtain and maintain a given therapeutic blood concentration of drug based on average pharmacokinetic parameters. We can apply this concept of infusion system not only to anesthetics but also to any kinds of intravenous drug infusion including antibiotics in the future.
Anesthetics
;
Anti-Bacterial Agents
10.Prophylactic antibiotics administration in acute appendicitis.
Chang Beom CHO ; Kyung Hwan PARK
Journal of the Korean Surgical Society 1991;41(5):662-666
No abstract available.
Anti-Bacterial Agents*
;
Appendicitis*