No Abstract Available.
Anisometropia*

we investigated the effect of spherical lens-induced anisometropia on dynamic stereoacuity. Twenty subjects with normal binocular function without past ophthalmic disease history were examined for the effect of anisometropia on the viasual acuity, static and dynamic stereoacuity created with spherical lenses in 0.5D stepwise manner before dominant eye from -2.0D to +2.0D. Dynamic stereoacuity was measured by new computer program. And we investigated the effect of anisometropia on dynamic stereoacuity as the power of the lenses was increased and the effect of plus lens vs minus lens on the dynamic stereoacuity. As a result, dynamic stereoacuity decreased statistically significantly as the power of the spherical lenses increased. And the plus 1.5D and 2.0D lens showed more deteriorating effects on dynamic stereoacuity than the corresponding minus power lenses, respectively. No statistically significant correlation was found between static and dynamic stereoacuity at each spherical lens diopter.
Anisometropia* ; Telescopes

Objective: To describe the clinical profile of patients with amblyopia seen at a Philippine tertiary hospital. Methodology: This was a cross-sectional study utilizing a chart review of children ages 6 months to 18 years old diagnosed with amblyopia at a Philippine tertiary hospital. Records with complete entry of history and ocular examinations were included. Verbal children with best-corrected visual acuity in both eyes of less than 6/15 or a 2 line difference between eyes were considered amblyopic. Response to alternate occlusion or refixation patterns was used as a basis for diagnosing amblyopia in pre-verbal children. Patients with visual deprivation amblyopia such as from cataract who had undergone lens extraction and optical correction were included. Results: There were 334 patients included in the study. The mean age was 5±3 years with 52% being male. Deprivation type of amblyopia was present in 192 (58%) patients, strabismic type in 81 (24%), and refractive type in 61 (18%). No sex predilection was observed. Majority of the patients were 3-6 years old on initial consult. Cataract was the most common cause of deprivation amblyopia affecting 127 (66%) patients. Strabismic amblyopia was present in 58 patients with 74% being esotropic. Anisometropic refractive amblyopia was more common at 37 (58%) than isometropic refractive amblyopia. Conclusion Visual deprivation amblyopia was the most common cause of amblyopia in a Philippine tertiary hospital.
Amblyopia ; Cataract ; Anisometropia ; Strabismus

Objective: To determine the visual outcome of amblyopia treatment and describe the relationship between age of onset and consult, compliance as measured by a patch diary, amblyopia subtype, and severity with the final visual outcome. Methods: Thirty-two consecutive, newly-diagnosed cases of amblyopia, aged 3-8 years on initial consult, with no history of prior amblyopia treatment, were included. Patching was done based on current AAO recommendations and patients were followed up monthly for 6 months. Treatment success was defined as best corrected visual acuity (BCVA) better than 20/30 (0.17LogMAR), or a 3-line improvement from baseline, or stable isoacuity for at least 3 months. Treatment failure was defined as no improvement of BCVA after 3 months of occlusion therapy or a regression of 2 lines. Descriptive and correlation statistics were performed comparing age of onset and consult, amblyopia subtype, severity, and compliance with the main outcome measure of BCVA at 6 months. Results: Sixteen (50%) attained treatment success. Patients seen earlier (age 2-5 years) had higher rates of success (75%) than those seen later (age 6-8 years) (35%). A moderately strong negative correlation (r=-0.48, p=0.01) existed between severity of amblyopia and final BCVA at 6 months. overall compliance to patching was 88±18%, with good compliance in the success group (92%) compared to fair compliance in the failure group (84%) and a moderate correlation between compliance and BCVA (r=0.37, p=0.05). Conclusion Treatment success was related to severity, compliance, and younger age of treatment. In the presence of good compliance, severity was a strong prognostic variable.
Amblyopia ; Compliance ; Sensory Deprivation ; Anisometropia

PURPOSE: To determine postoperative astigmatic changes after surgery for congenital ptosis and the astigmatic changes depending on surgical method and to discern cases of postoperatively developed anisometropia or amblyopia. METHODS: Fifty-one patients who underwent surgery due to congenital ptosis were reviewed. Refraction or cycloplegic refraction was conducted preoperatively and 3 to 6 months after surgery to measure astigmatic changes. Astigmatic changes in operated eyes were compared to control eyes. Astigmatic changes were compared depending on surgical method. RESULTS: The mean astigmatism was 1.33+/-1.29D preoperatively and 1.48+/-1.13D postoperatively (P=0.10) and the mean astigmatic change in the ptotic and control eye was an increase in cylinder +0.56+/-0.55D and +0.68+/-0.72D (P=0.37). The mean astigmatic change of patients receiving frontalis sling was +0.57+/-0.67D which was similar to those who received levator resection (+0.56+/-0.50D). Newly developed anisometropia was found in three patients postoperatively due to an increase in astigmatism, but newly developed amblyopia was not found. CONCLUSIONS: The increase of astigmatism by ptosis surgery was not statistically significant and there was no statistically significant difference when accounting for surgical method. However, it is necessary to monitor refractive error carefully in younger patients to prevent amblyopia because postoperative increase of astigmatism can cause anisometropia.
Amblyopia ; Anisometropia ; Astigmatism* ; Humans ; Refractive Errors

No abstract available.
Anisometropia* ; Humans ; Myasthenia Gravis* ; Twins, Monozygotic*

PURPOSE: To evaluate the effects of occlusion therapy on anisometropic amblyopia and investigate the factors that influence on the final vision. METHODS: Fifty two patients with anisometropic amblyopia, whose age ranged from 3 to 12 years, were treated with full and partial occlusion therapy. RESULTS: The degree of anisometropia was 3.23+/-1.99 D in hyperopia group and 2.00+/-0.98 D in myopia group. The best corrected visual acuity and final vision were 0.29+/-0.14 and 0.52+/-0.22 in hyperopia group, while 0.34+/-0.16 and 0.63+/-0.16 in myopia group. But statistically significant difference was not found between two groups. The best corrected visual acuity was significantly correlated with the degree of anisometropia. The final vision was also significantly correlated with the degree of anisometropia. As expected, the final visual acuity was strongly correlated with the best corrected visual acuity. But no statistically differences were found based on the age of initial treatment and sexual difference. CONCLUSIONS: The severity of amblyopia and the effect of occlusion therapy were more correlated with the degree of anisometropia than the age of initial treatment and the type of anisometropia.
Amblyopia* ; Anisometropia ; Humans ; Hyperopia ; Myopia ; Visual Acuity

PURPOSE: The Frisby Davis Distance (FD2) Stereotest has been introduced to measure distance stereoacuity. The purpose of this study is to establish the range of normal distance stereoacuity responses on the FD2 Stereotest in a normal population. METHODS: This study comprised 65 subjects. All had best corrected vision of 20/25 or better in each eye at distance, 1.0 diopters or less of anisometropia, 8 prism diopters or less of phoria on alternate cover test at both distance and near, binocular fusion on the Worth four dot test and stereopsis on Titmus test. Distance stereoacuity was measured using the FD2 stereotest. RESULTS: The mean age of the subjects was 18.6 years (range, 3 to 59). The mean stereoacuity for distance was 15.61+/-10.41 sec (seconds of arc), and the mean stereoaucity of the subject over 10 years old was 12.98+/-6.86 sec. Results of the test-retest variability as well as of different test distances revealed no statistically significant differences. Of 60 subject with one eye closed, 11 (18.3%) of them detected the disparity of 200 sec but none could detect smaller disparity except one. CONCLUSIONS: The FD2 Stereotest is reliable test without test distance variance. The results of this study can be used as a normative data of distance stereoacuity by FD2.
Anisometropia ; Child ; Depth Perception ; Humans ; Strabismus ; Telescopes

To determine and compare the AC/A ratio in normal subjects, the AC/A ratio was measured by three different methods;near gradient method, distant gradient method and heterophoric method. The 33 normal subjects were enrolled in this study. All of them met the following criteria:(1)no known ocular disorders such as anisometropia, strabismus, and amblyopia.;(2)refractive error under -4D and corrected visual acuity more than 0.9.;(3)stereoacuity of 40 arc sec on Titmus test. The AC/A ratio was measured under full correction of the refractive error. Ages ranged from 6 to 25 years with a mean age of 16 years. The mean refractive error of the subjects was -1.33 D in right eye and -1.38 D in left eye. The near gradient method showed a mean AC/A ratio of 3.36:1 ranging from 1.33 to 4.67 ;the distance gradient method showed a mean ratio of 1.79:1 ranging from 0.67 to 3 ;and the heterophoric method showed a mean ratio of 5.71:1 ranging from 4.13 to 9. There was no significant difference in the AC/A ratio between the sexes and in the AC/A ratio between ages less than 11 years and more than 11 years. Different AC/A ratio values were obtained using three different methods. Among the three methods, the heterophoric method tended to give a higher value than the gradient method, and the near gradint method tended to give a higher value than the distance gradient method.
Anisometropia ; Refractive Errors ; Strabismus ; Visual Acuity

PURPOSE: To investigate the change of refractive error between the full-correction and under-correction treatment groups of myopic anisometropic patients. METHODS: This study included 36 patients who had no amblyopia with myopic anisometropia > 3.00 diopters (D) and less than 6.00 D using the cycloplegic refraction test. The patients were divided into two groups involving the full-correction of both eyes (group 1) or full-correction on the less myopic eye and under-correction with −0.50 D of the more myopic eye (group 2). We monitored refractive changes every 6 months for 24 months. RESULTS: At the first visit, the mean refractive error of the less myopic eye was −0.68 ± 0.54 D and that of the more myopic eye was −4.22 ± 0.77 D in group 1. The mean refractive error of the less myopic eye was −0.75 ± 0.58 D and that of the more myopic eye was −4.36 ± 0.73 D in group 2. There was no significant difference between the groups (p = 0.713 and p = 0.585, respectively). At 24 months, the mean refractive errors of group 1 were −1.27 ± 0.54 D and −4.88 ± 0.81 D, respectively, and that of group 2 were 1.38 ± 0.54 D and −5.59 ± 1.01 D, respectively. The mean refractive error of the less myopic eyes showed no significant difference between both groups (p = 0.555), but that of the more myopic eyes was significantly different (p = 0.027). Between both groups, the degree of anisometropia at 24 months was 3.61 ± 0.60 in group 1 and 4.20 ± 0.86 in group 2. Group 2 showed a significant difference and more severe anisometropic changes (p = 0.022). CONCLUSIONS: Full correction of myopic anisometropia without amblyopia is a better method for reducing the progression of anisometropia.
Amblyopia ; Anisometropia ; Humans ; Methods ; Myopia ; Refractive Errors