No abstract available.
Angiokeratoma* ; Hypertrophy*

No abstract available.
Angiokeratoma* ; Fabry Disease*

No abstract available.
Angiokeratoma ; Child ; Humans

Angiokeratomas represent vascular lesions and are histologically characterized by superficial vascular ectasia and overlying acanthosis and/or hyperkeratosis. Angiokeratomas can be classified into five types, with angiokeratoma circumscriptum representing the least common of the five types. Angiokeratoma circumscriptum presents at birth and frequently occurs unilaterally on the leg. Herein, we report a rare case of long term angiokeratoma circumscriptum (twelve years) on the right chest, discovered following the excision of a lipoma from the same area.
Angiokeratoma ; Dilatation, Pathologic ; Leg ; Lipoma ; Parturition ; Thorax

Angiokeratoma is a rare, cutaneous disorder that typically manifests as multiple lesions and is often associated with a number of metabolic disorders. Although solitary cutaneous forms have been reported, localized lesions within the oral tongue have not been described so far. We report a 16-year-old male with a solitary pigmented lesion of his oral tongue tip. The lesion was a mixture of purple and white in color with a granulomatous appearance. Histopathological examination of the lesion obtained by excisional biopsy showed features consistent with angiokeratoma. We report a case of solitary angiokeratoma of the oral tongue tip and review the clinical and pathologic features of this unusual condition.
Adolescent ; Angiokeratoma ; Biopsy ; Humans ; Male ; Tongue

Transepidermal elimination is a well known phenomenon describing cases where foreign materials or altered dermal constituents are removed from dermis through epidermis. The phenomenon of transepidermal elimination may occur as a primary process or as a secondary process. A 36-year-old women presented with three black papules on the ventral side of her right second toe for 1 year. Because of poliomyelitis, the lesion had been irritated repeatedly. The histopathology of the lesion showed solitary papular angiokeratoma with transepidermal elimination. In this case, we postulated that transepidermal elimination of this case could have developed through repetitive physical trauma.
Adult ; Angiokeratoma ; Dermis ; Epidermis ; Female ; Humans ; Poliomyelitis ; Toes

Cutaneous horn is a clinical description for a protruding mass of keratin, which may arise from benign and malignant lesions. There have been 21 cases of cutaneous horns reported in Korea: 19 cases in adults, 2 cases in children, and no case in infants. We report the case of an 8-month-old girl who presented with a pea-sized, hyperkeratotic nodule on the dorsum of the right foot. Histopathologic examination confirmed the nodule to be a cutaneous horn arising from an angiokeratoma.
Adult ; Angiokeratoma* ; Animals ; Child ; Female ; Foot ; Horns* ; Humans ; Infant ; Korea

Scrotal Leiomyoma is an extremely rare benign tumor originating from the tunica dartos muscle. It usually presents as a solitary, painless, unilateral, slow growing mass that is occasionally pedunculated. We report a case of a 31-year-old man, presenting clinically with multiple papules resembling Angiokeratoma of Fordyce but with a histopathologic diagnosis of Scrotal Leiomyoma. Scrotal Leiomyoma has not been reported to present clinically in this manner and our report is probably the first of its kind.

Angiokeratomas are present in approximately 0.16% of the population, with only 14% classified as the Fordyce type. Angiokeratomas of Fordyce are mainly found on the scrotum, with very rare occurrences on the glans penis or penile shaft. Currently, there are no established guidelines in the management of angiokeratomas. Since angiokeratomas are vascular in nature, lasers which target the chromophore oxyhemoglobin can be used, hence the use of the 578-nm yellow laser in this case.

This is a case of a 34-year-old Filipino male with a 22-year history of violaceous papules on the penile shaft gradually increasing in size, with complaints of bleeding from the lesions during coitus, significantly affecting the patient’s quality of life. Physical examination revealed few, well-defined, round, violaceous hyperkeratotic papules on the penile shaft, the largest measuring 4x4x4 mm. Dermoscopy revealed several, well-demarcated, round, erythematous to violaceous lacunae with whitish veil. Histopathology also revealed findings consistent with angiokeratoma.

Non-scrotal or penile angiokeratoma of Fordyce is a very rare benign vascular tumor that can adversely affect patients’ quality of life, particularly due to the potential discomfort brought about by bleeding during coitus. Traditional therapeutic modalities may lead to scarring, hence the emerging trend on the use of vascular lasers. After two sessions of yellow laser, our patient expressed satisfaction with the results with an improved overall quality of life. The effectiveness, minimal scarring potential, and relatively safe side effect profile of these vascular lasers make them a promising treatment option for angiokeratomas.

Acral pseudolymphomatous angiokeratoma of children (APACHE) is a recently recognized, rare clinical entity with only 20 reported cases worldwide. It is characterized by unilateral eruptions of multiple angiomatous papules, mostly on acral areas and mainly in children, although some cases have also been reported with involvement of non-acral areas and occurring in adults. The histopathologic examination revealed diffuse dermal infiltrates of lymphohistiocytes and thick-walled vessels lined with prominent plump endothelial cells. APACHE is a cutaneous pseudolymphoma, rather than a vascular neoplasm, because of distinct histopathologic and immunohistochemical findings. We report a case of a 9-year-old girl who presented with multiple angiomatous papules on her right upper arm. The histopathologic and immunohistochemical findings in our patient were consistent with a diagnosis of APACHE.
Adult ; Angiokeratoma* ; APACHE ; Arm ; Child* ; Diagnosis ; Endothelial Cells ; Female ; Humans ; Pseudolymphoma ; Vascular Neoplasms