1.Prevalence of nasopharyngeal carcinoma among patients with nasopharyngeal mass in a Philippine tertiary training hospital.
Hasmin Hannah R. Lara ; Angelo Monroy
Philippine Journal of Otolaryngology Head and Neck Surgery 2016;31(1):35-38
OBJECTIVES: To determine the prevalence and identify the types of Nasopharyngeal Carcinoma (NPCA) among patients with nasopharyngeal mass seen at a tertiary university training hospital in the Philippines from January 2006 - July 2012 and identify possible factors associated with nasopharyngeal carcinoma.
METHODS: A retrospective cross-sectional study was performed at a tertiary university training hospital among cases (n=179) seen with nasopharyngeal mass at the ENT outpatient department. Histopathology results and patient medical charts were collected and reviewed after IRB approval. The age at diagnosis, sex, place of residence, occupation and chief complaint was compared among patients with positive histopathology of NPCA only.
Design: Retrospective, cross sectional study
Setting: Tertiary Private University Training Hospital
Participants: One hundred seventy nine (179) patients with nasopharyngeal mass
RESULTS: Ninety six (54%) cases with nasopharyngeal mass seen at the ENT outpatient department were positive for nasopharyngeal malignancy. The remaining 83 (46%) cases with nasopharyngeal mass had a benign histopathology. NPCA was more common among males (58%) than females (42%). The most common form of NPCA was non-keratinizing undifferentiated NPCA (47%) followed by poorly differentiated squamous cell carcinoma in 18 (19%). The most common chief complaint was a neck mass, followed by decreased hearing.
CONCLUSION: There was a higher proportion of nasopharyngeal malignancy among male patients with nasopharyngeal mass, and the most common chief complaint was a neck mass. Future research should integrate data with other hospital institutions to obtain more accurate demographic data of the local prevalence of NPCA. A detailed record of the ethnicity, diet, occupation, smoking history and family history of cases should be obtained to correlate possible risk factors of NPCA among patients with nasopharyngeal mass in our setting.
Human ; Male ; Female ; Middle Aged ; Adult ; Young Adult ; Carcinoma ; Epidemiology ; Prevalence
2.Kikuchi-Fujimoto Disease in a Filipino Boy: A Case Report.
Jenina Rachel D. J. ESCALDERON ; Angelo A MONROY
Philippine Journal of Otolaryngology Head and Neck Surgery 2019;34(2):35-38
OBJECTIVE: To report a case of a 12-year-old boy with Necrotizing Lymphadenitis (Kikuchi-Fujimoto disease) presenting as lymphadenitis secondary to multiple diagnosis.
METHODS:
Design : Case Report
Setting: Tertiary Private Hospital
Patient: One
RESULTS: A 12-year-old boy consulted for two-month history of cervical lymphadenopathy with the underlying cause remaining unclear despite multiple consults, diagnosis and medical treatment. Lymphoma was considered and excision biopsy with further investigations confirmed a diagnosis of Kikuchi-Fujimoto disease. Supportive management was given with no recurrence of symptoms noted on 18 months of follow up.
CONCLUSION: Kikuchi-Fujimoto disease in this case was a diagnosis of exclusion. Even with a proper history and physical examination, experts in otolaryngology can be misled to manage this case as malignant. Awareness of the disease and appropriate examinations including immunohistochemistry are important for a timely diagnosis and proper intervention.
KEYWORDS: lympadenitis; Kikuchi-Fujimoto disease; lymphoma; cervical lymph nodes
Human ; Male ; Child Preschool (a Child Between The Ages Of 2 And 5) ; Histiocytic Necrotizing Lymphadenitis ; Lymphoma