1.A pilot study on the safety and efficacy of Abelmoschus Esculentus (Okra) 5% extract in the treatment of non-bullous impetigo among paediatric patients at Jose R. Reyes Memorial Medical Center, Department of Dermatology.
Andrea Marie Bernales-Mendoza ; Daisy King-Ismael
Journal of the Philippine Medical Association 2021;100(1):80-86
INTRODUCTION
Impetigo Is a common, contagious,
superficial skin infection most commonly
presenting as erythematous crusting papules and
pustules on the face and or extremities. The
pathogens usually implicated in this skin disease
are gram- positive organisms including
Staphylococcus aureus, and less frequently, group
A β-hemolytic Streptococcus pyogenes. In
JRRMMC, Department of Dermatology, this disease
always ranks in the top 1 O most common skin
diseases annually. Treatment options for this
disease include topical and oral antibiotics
depending on the condition's severity. Mupirocin
and Fusidic acid are considered as gold standard in
the treatment of impetigo.
2.Unmasking tumors: A case of a CD30-Negative MycosisFungoides masquerading as Erythema NodosumLeprosumin a filipino male.
Ma. Cristina Georgina T. Paloma ; Andrea Marie Bernales-Mendoza
Journal of the Philippine Medical Association 2023;101(2):29-32
Mycosis Fungoides is the most common type of primary
cutaneous lymphoma. Early in its course, it usually
presents as erythematous patches and plaques similar
to a lot of cutaneous conditions. A 68-year-old male
presented with a 13-year history of multiple
erythematous patches and plaques on the arms and
trunk. The lesions were pruritic and chronically relapsing
over the years, temporarily relieved by topical
corticosteroids. Thereafter, there was onset of multiple
nodules on the trunk, extremities and face. Initial biopsy
was done by a different dermatologist, revealed
Hansen’s Disease, Borderline Borderline spectrum.
Fitefaraco stain was positive but no bacillary index was
given. The patient was subsequently started on
rifamcpicin 600mg/capsule once a day, Ofloxacin
400mg/tablet once a day, and Minocycline
100mg/capsule once a day. The lesions were noted to
worsen, eventually developing ulcerations over the trunk
and extremities prompting referral to our institution. The
biopsy results were as follows: Cutaneous T-Cell
Lymphoma, diffuse cluster of differentiation (CD) 3
staining, focal CD20 staining, and negative FiteFaraco
stain. The histopathologic findings combined with the
clinical presentation led to the diagnosis of Mycosis
Fungoides. He was then referred to medical oncology
for proper staging and definitive management. The
prognosisof Mycosis Fungoides is generally dependent
on the stage as determined by the extent of skin
involvement as well as presence of lymph node invasion
and/or metastasis.
Mycosis Fungoides
;
Lymphoma
;
T-Cell
;
Cutaneous
3.Concordance of acid-fast stain result and histopathologic vs clinical diagnosis of leprosy: A three-year retrospective study in a Tertiary Government Hospital and Sanitarium in the Philippines
John Benjamin B. Gochoco ; Andrea Marie Bernales-Mendoza
Acta Medica Philippina 2024;58(Early Access 2024):1-7
Objectives:
In the Philippines, there has been a lack of information on the concordance between classifications
of Hansen’s disease or leprosy clinically, histopathologically, and with AFS results. The study ultimately aimed to
determine the concordance between the clinical diagnosis, histopathological results, and AFS results of patients with leprosy seen at the Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium (DJNRMHS).
Methods
This is a descriptive, retrospective, single-center study conducted at the DJNRMHS, a tertiary government hospital and one of the last remaining sanitaria in the country located in northern Metro Manila in the Philippines. The study reviewed and included all the patient records from the years 2017-2019 which included skin biopsy results and slit-skin smear with AFS. Leprosy patients were then classified based on the following classifications: World Health Organization (WHO) and Ridley-Jopling classifications; and the concordance of clinical diagnosis vs the histopathologic findings and clinical diagnosis vs AFS results were determined using kappa testing.
Leprosy
;
Biopsy