Background: The coexistence of acute kidney injury (AKI) in sepsis contributes significantly to morbidity and mortality rates. Traditional diagnostic markers still pose variable limitations in early AKI prediction. The use of renal angina index (RAI) as a clinical predictive tool for AKI is an emerging concept. Objectives: To determine the diagnostic accuracy of RAI in predicting AKI in patients with sepsis Methodology This is a five-year retrospective cohort study conducted at the Philippine General Hospital (PGH). Records of eligible patients with sepsis were reviewed. RAI was calculated based on the composite of risk factors and clinical evidence of injury on day 0 of admission stratifying subjects into two groups: RAI (-) and RAI (+) for those with scores ≥ 8. Prediction of AKI with the RAI was analyzed.
Acute Kidney Injury ; Sepsis

Introduction: Urinary tract infection (UTI) is a common reason for outpatient consults. It is almost always in the Top Ten consults at the sick-child clinic of a tertiary hospital. However, a study concerning the incidence and clinical and laboratory profiles of UTI in the Philippines has yet to be documented. Objectives: To determine the incidence rate and clinical and laboratory profiles of UTI among patients who consulted at the pediatric outpatient clinic of a tertiary hospital. Methods: All patients 0 to 12 years, who were UTI suspects and consulted at the Sick-Child Clinic of a tertiary hospital from January to December 2006 were included in the study. Patients who had recurrent UTI or history of previous UTI and those with co-morbidities such as anatomic and/or functional problems involving the urinary tract were excluded. Chart review was done and the following were noted: demographics and clinical and laboratory characteristics. Results: Four hundred twenty three patients were included in the study. The incidence rate was 30 per 1000 persons (95% CI). 54% percent were female. The majority of the patients were between 7 to 12 years of age. The most common presenting symptoms were fever, abdominal pain, vomiting, and dysuria. Only 25 patients had urine culture done and only 8 had positive results, mostly with E. coli. The most common antibiotics used were Cotrimoxazole, Cefuroxime, and Amoxicillin. Conclusion: The incidence rate is higher compared to other studies done in general practice. The presenting signs and symptoms were however similar. Important to note is the high incidence of patients who did not follow up. It is also noted that the gold standard for the diagnosis of UTI, which is the urine culture is very seldom requested. This may lead to the over- or maybe under-diagnosis of UTI and its eventual mismanagement. Therefore, it is recommended that the approach to the diagnosis and management of UTI in children should be reviewed.
Human ; Male ; Female ; Child ; Child Preschool ; Infant ; Infant Newborn ; URINARY TRACT INFECTIONS ; INCIDENCE ; DIAGNOSIS

A 14 year old male from Quezon City Manila was admitted due to oliguria. He presented with 7 days of intermittent fever associated with malaise, photophobia with redness of the eyes. A few hours before admission, he developed repetitive vomiting with decreased urine output. He denied any muscle pain, change in his sensorium or seizure episode. He had a history of wading in flooded waters.
Oliguria ; Fever ; Photophobia