With the improvement of the therapy and the drugs we known more results in a therapeutic ambitious goals of juvenile idiopathic arthritis.Selection of individualized sequential therapy is beneficial to the recovery of the disease.

OBJECTIVE: To study the protective effects of nimesulide, a COX- 2 selective inhibitor on experimental gastric ulcer in rats. METHODS: The gastric ulcer model was established in rats by intragastric administration them with indometacin, 5 min later, which were assigned to receive nimesulide at different dosages ( 200, 100, and 50mg? kg- 1) , 6h later, all the rats were sacrificed. The primary outcome measures were the area of ulcer, levels of SOD, MDA, and GSH in sera and gastric mucosa. RESULTS: As compared with model group, in nimesulide ( at different dosage) groups, the area of ulcer was markedly decreased, level of MDA was decreased while activities of SOD and GSH were increased ( P

目的观察重组人表皮生长因子与生理盐水湿敷对脑卒中患者Ⅱ～Ⅲ期压疮的临床效果，总结护理措施。方法将60例脑卒中Ⅱ～Ⅲ期压疮患者分为观察组和对照组。观察组30例采用重组人表皮生长因子及生理盐水湿敷换药；对照组采用常规护理方法。比较7 d后的愈合率及有效率及总愈合时间。结果观察组与对照组比较，愈合时间缩短，7 d愈合率及有效率提高（P＜0.05）。结论重组人表皮生长因子与生理盐水湿敷对治疗脑卒中患者Ⅱ～Ⅲ期压疮效果显著。

AIM: To establish a RP HPLC method for the determination of 4′ O ? D glycosyl 5 O methylvisamminol in Jingfuzhiyang Granules (Herba Schizonepetae, Fructus kochiae, Radix Saposhnikoviae, Fructus Crataegi, etc.). METHODS: The sample was separated on Turnner Kromasil C 18 column (4.6mm?200mm,5?m) with mobile phase of methanol 0.05mol?L -1 potassium dihydrogen phosphate acetic acid isopropyl alcohol (85∶170∶4∶4,v/v). The detection wavelength was set at 254nm and the flow rate was 1.0mL?min -1 . The column temperature was 30℃. RESULTS: The calibration curve was linear in the range of 0.0606～0.606?g (r=0.9994). The average recovery was 92.2%. CONCLUSION: This method proves to be relatively simple and accurate, and available for the quality control of Jingfuzhiyang Granules

In this article,the author introduced their experiences,investigated the importance,connotation,and strategy of aesthetic education to the medical students and put forward some suggestions on aesthetic education in medical education in order to cultivate multiple qualifications of medical students.

The impact of market economy and the pressure of professional title upgrading have posed an effect on the psychology and behavior of clinic research personnel in their research activities.Clinic research personnel should positively modify their think- ing,regulate their scientific behavior and recognize correctly the guidance of their research in medical field so as to play and im- portant role as a motivation to the improvement of medical level and the whole development of the science.

This article discusses the basic content and the origin of life education,the urgency of life education in college,the implementation ways of life education,in order to effectively reduce and prevent negative phenomena.

In view of the origin of doctor-patient relations,the rights and obligations of the parties,and their corresponding legal responsibilities,doctor-patient relations may be divided into three categories,namely,medical contract relationship,undefined medical management relationship,and forced medical relationship.Of these three,the first two are civil relationships while the last an administrative one.This paper deals in depth with the legal nature and character of three types of doctor-patient relations,based on principles of civil and administrative laws.

Humanity quality is the essential manifestation of general characters such as hu-man knowledge and human spirit.In this article,we investigated the importance,meanings and measures of the education of humanity quality in medical teaching in order to reinforce the education of humanity quality of medical students and train excellent medical talents with advanced professional technology,magnificent professional ethics and healthy mental quality.

Dr. Rachel Yudkowsky et. al. have published the paper in Academic Medicine [2008,83 (10 Suppl):S13–S16] demonstrating a reformed Angoff method in which items were assigned to "Yes/No/Maybe" three-level categories for judges to estimate whether a borderline students would or would not accomplish each item,compared with "Yes/No" two-level categories. Five judges were provided three-level Angoff ratings for seven checklists used in a clini-cal skills exam for fourth-year students. 45% of 121 items had at least one "Maybe" rating. About 10% of all ratings were in the "Maybe" category. Case failure rates varied considerably depending on the simulated severity of ratings. Overall failure rates were not substantially impacted. The three-level Angoff retains the cognitive simplicity of the Yes/No Angoff while addressing the challenge of items midrange for the borderline candidate and avoids the potential bias.