Objective:To explore the relationship between the latent classes of online emotion regulation among college students and the distribution difference of different types on variables such as gender,grade,ages of surfing the net and so on.Methods:Totally 421 college students were assessed with Online Emotion Regulation Questionnaire (OERQ).Latent class analysis was used to identify online emotion regulation classes,and then analyzed the distribution of latent classes among different genders,grades and ages of surfing the net.Results:Two latent classes of online emotion regulation were identified,including online emotion inhibiting/ignoring class (37.6％) and online emotion venting class (62.4％).The prevalence of online emotion venting class among girls (56.6％ vs.3.8％),sophomores (36.3％ vs.11.9％),juniors (23.4％ vs.3.1％),those with more than 36 months of surfing the net (31.6％ vs.18.8％) were significantly higher than the other of the respective kind.Whereas,the rate of inhibiting/ignoring class among boys (32％ vs.7.6％),freshmen (20％ vs.5％) were significantly higher.Conclusion:It suggests that online emotion regulation could be divided into two different latent classes and prevalence of each class is significantly different in different genders,grades,and ages of surfing the net.

Objective To investigate the clinical efficacy of acupuncture in treating subhealth.Methods One hundred and fifty-four patients with subhealth were allocated, using a random number table, to observation and control groups, 77 cases each. The control group received basic treatment by diet, exercise, rest and rest and psychological intervention and the observation group, acupuncture therapy in addition. Subhealth scale subscores and the 36-Item Short-Form Health Survey (SF-36) subscore were recorded and blood biochemical indicators were measured in the two groups before and after treatment. the clinical therapeutic effects were compared between the two groups.Results The total efficacy rate was 96.1% in the observation group and 83.1% in the control group; there was a statistically significant difference between the two groups (P<0.05). There were statistically significant pre-/post-treatment differences in subhealth scale subscores in the two groups (P<0.05). After treatment, sleep, digestion, urination, positive emotion, ability and social relation subscores were higher, and fatigue, discomfort and negative emotion subscores were lower in the observation group than in the control group (both P<0.05). There were statistically significant pre-/post-treatment differences in blood biochemical indicators in the two groups (P<0.05). After treatment, blood uric acid (UA), total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) were significantly lower and high-density lipoprotein cholesterol (HDL-C) was significantly higher in the observation group than in the control group (both P<0.05). The 36-Item Short-Form Health Survey (SF-36) subscore were higher in thetwo groups after treatment than before treatment (P<0.05). After treatment, physiological function, role-physical, role-emotional, body pain and general health subscore were significantly higher in the observation group than in the control group (P<0.05).Conclusions Acupuncture helps to improve subhealth status in population, regulate blood biochemical indicators and enhance the clinical therapeutic effect to raise the quality of life in the patients.

Objective:To explore the correlation between fibrinogen levels and chemotherapy effect of platinum drugs in ovarian cancer patients. Methods:Totally 91 ovarian cancer patients and 95 patients with benign ovarian tumor were involved in our retrospec-tive study, and the associations between preoperative fibrinogen levels and clinic pathologic parameters in the patients were analyzed. Results:High fibrinogen levels were observed in 36.26％ (33/91) of the patients with ovarian cancer ( >4.0 g·L-1), which was significantly higher than that in the patients with benign tumor(P<0. 05). The high fibrinogen levels in ovarian cancer patients were associated with the higher FIGO stage and poor chemo-response, while were not associated with the patients' age, CA-125 levels and histological type and grade (P>0. 05). More importantly, no correlation was observed between high blood fibrinogen and CA-125 lev-els (P>0.05). Chemotherapy resistance was more in the patients with high fibrinogen levels than that in the other patients(P <0. 05). The OR value of high fibrinogen levels was 3. 571, 95％ CI was 1. 276-10. 000, which suggested high fibrinogen level is a dangerous factor for chemotherapy resistance. Conclusion:The study suggested that elevated fibrinogen level was a dangerous factor for chemotherapy response, which has a potential role in the poor prognosis of ovarian cancer patients independent of CA-125.

Objective To explore the effect of treadmill training on expression of glial fibrillary acidic protein (GFAP) and brain-derived neurotrophic factor (BDNF) after cerebral ischemia-reperfusion in rats. Methods 30 male Wistar rats were randomly divided into sham group, model group and treadmill training group, with 10 rats in each group. The latter 2 groups were modeled with middle cerebral artery occlusion for 2 hours and reperfusion. The treadmill training group underwent treadmill exercise on the 3rd day after modeling for 12 days. Neurological function was evaluated with modified Neurological Severity Scores (mNSS). The neuronal pathological change in ischemic cortex was observed with HE staining. The expressions of GFAP and BDNF in cortex were determined by Western blotting. Results Com-pared with the model group, the mNSS scores decreased in the treadmill training group (F=9.931, P<0.01), the pathological damage in the ischemia cortex significantly lessened, and the expressions of GFAP (t=6.73) and BDNF (t=3.78) increased (P<0.05). Conclusion Treadmill training may increase the expression of GFAP and BDNF after cerebral ischemia-reperfusion in rats, and promote the recovery of neurologi-cal function.

Anesthesia machine is an important equipment of clinical surgery. This paper introduces several abnormal conditions of the anesthesia machine, especially the judgment and the common fault check of the tidal volume for reference.
Anesthesia ; methods ; Anesthesiology ; instrumentation ; Humans ; Tidal Volume

ObjectiveTo analyse the prognostic factors of acute respiratory distress syndrome (ARDS) of children by comparing mortality in ARDS. MethodARDS type ,treatment process if there were multiple organ dysfunction syndrome (MODS), and whether family members actively cooperated with the treatment factors in 38 children with ARDS were analyzed. ResultsARDS of the original mortality of sepsis was the highest[ 66.67％ ( 14/21 )]; treatment process combined with MODS in 8 cases, 6 died, the mortality up to 75.00％ (6/8), significantly higher than combined without MODS [40.00％ (12/30)],there was significant difference (P ＜ 0.05); family members actively cooperated with the treatment could reduce mortality of children (P ＜0.05); PaO2 and PaO2/FiO2 value:pulmonary-exterior type was lower than pulmonary-interior type, combined with MODS was lower than combined without MODS, family members actively cooperated with the treatment was lower than family members inactively cooperated with the treatment (P ＜ 0.05 );PaCO2 value:pulmonary- exterior type was lower than pulmonary-interior type, family members actively cooperated with the treatment was lower than family members inactively cooperated with the treatment (P ＜ 0.05 ) ; pH: pulmonary-exterior type was higher than pulmonary-interior type, combined with MODS was higher than combined without MODS, family members actively cooperated with the treatment was higher than family members inactively cooperated with the treatment (P ＜0.05);the critical illness score in family members with a positive attitude was higher than that in family members with a negative attitude (P ＜ 0.05).ConclusionThe primary disease of sepsis, associated with MODS, the family members with a negative attitude toward the treatment affect the prognosis of children with ARDS.

ObjectiveTo investigate the clinical manifestation and therapy method of hyperthyroidism accompanied by liver damage. MethodsTo analyze the clinical data of 38 cases those with hyperthyroidism accompanied by liver damage and divide them by damage degree into two groups,one of which contains mild impairment of 26 cases and the other one contains severe impairment of 12 cases. Then make a analysis about the comparison of the two groups on the level of thyroid disorders and the correlation with liver damage. ResultsOf all the 38 cases 26 (68. 4％ ) cases have slight liver damage and 12(31.6％ ) cases have severe liver damage. The symptom:26 cases have abdominal distension in different degree, weakness, sickness, port colored urine, aurigo and so on. 2 cases have hepatomegaly. 10 cases have no obvious symptoms of liver damage. The FT3 and FT4 in the severely liver-impaired group is obviously higher than the slightly liver-damaged group( (t =3.16,3.27, allP ＜ 0. 05 ) ,while the TSH is obviously lower( t =3.09 ,P ＜ 0.05 ). 38 cases are all healed and the symptom of hyperthyroidism has got under control. The cases of ATD therapy or 131 I therapy are not any aggravated in liver damage. ConclusionHyperthyroidism may lead to liver damage whose level is directly proportional to the level of thyroid dysfunction. And the result can be different, even no any symptom.

BACKGROUND The effect of lipid-regulating therapy has been affirmed definitely in the first and second grade prevention of coronary arteriosclerotic cardiopathy, and Ginkgo biloba extract has a certain effect to lower blood lipid.OBJECTIVE: To investigate the effect of new Ginkgo biloba extract recipe (NGBR) on the blood-lipid level and the degree of hepa tic fatty degeneration in experimental hyperlipidemic rats. DESIGN:A randomized and controlled trial.SETTING: Department of Cardiology , Jinshan Hospital of Fudan University; Suzhou Institute of Traditional Chinese Medicine, Department of Pharmacology, Soochow University,MATERIALS: A total of 60 SD rats of clean grade, after one week adaptive feeding, were randomly divided into six groups: normal control group, hyperlipidemic model group, NGBR 20 mg/(kg·d), 40 mg/(kg·d)and 80 mg/(kg·d) groups, as well as lipanthyl 25 mg/(kg·d)group, with 10 in each group. 10METHODS: The rats in lipanthyl 25 mg/(kg·d), NGBR 20 mg/(kg·d), 40 mg/(kg·d) and 80 mg/(kg·d) groups were by gavage administrated 10 mL/kg, at 9:00-10:00 every morning; while the rats in normal control group and hyperlipidemic model group were given distilled water of the same volume. Except for the rats in normal control group, the rats in other five groups were by gavage given fatty emulsion 10 mL/kg, at 1:00-2:00every afternoon for 28 days consecutively. On the 29th day, all the rats were tested on serum total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), apolipoprotein AI (apoAI) and apolipoprotein B (apoB); at the same time the lives of the rats were taken out for pathological.examination of the degree of hepatic fatty degeneration. MAIN OUTCOME MEASURES:The blood-lipid changes and the degree of hepatic fatty degeneration of rats in each group RESULTS:Totally 60 rats involved all entered the final result analysis. ① Comparison of blood-lipid changes of rats in each group: The levels of TC and low density lipoprotein cholesterol (LDL-C) in hyperlipidemic model group were obviously increased, HDL-C level was decreased, as compared with those in normal control group there was a significant difference (P < 0.01); but the TG level was only slightly increased (P > 0.05). In the three NGBR groups the levels of TC, TG and LDL-C were obviously decreased(P < 0.05 or 0.01 ), and the levels of HDL-C, apoAI and apoB were increased to a certain grade, with in the NGBR 80 mg/(kg·d)group the difference being obvious(P < 0.05). ② Comparison of the degree of hepatic fatty degeneration of rats in each group: In pathological examination, the liver of rats in hyperlipidemic model group presented diffuse fat vacuoles; in NGBR 40 and 80 mg/(kg·d)groups, the degeneration levels reduced to a given degree, especially obvious in NGBR 80 mg/(kg· d)group. CONCLUSION:NGBR can effectively correct the lipid metabolism in hyperlipidemia, with a good preventive role to hyperlipidemia induced by feeding fatty emulsion.

Kawasaki disease(KD) is an acute,systemic vasculitis syndrome that primarily affects coronary arteries.The long-term prognosis depends on the severity of coronary artery leisions(CAL).Treatment with high-dose intravenous immunoglobulin(IVIG) within 10 days of the onset of fever is proven to decrease the incidence of CAL.Patients with IVIG resistance is at a high risk to be affected by CAL.How to predict IVIG resistance and CAL in the early stage is helpful for improving the outcome of Kawasaki disease.Thus,predictors of IVIG resistance and CAL for KD were reviewed in this article.

The human Dab2 gene has a variety of physiological functions,and plays important roles in various signal transduction pathways.Researches have shown that reduced expression of Dab2 was closely related to the occurrence and development in many malignant cancers,and Dab2 has been regarded as a tumor suppressor.This paper reviewed about multiple researches on the structure and functions of Dab2,and explored the specific mechanisms in oncogenesis.