China ; Humans ; Occupational Diseases ; prevention & control ; Occupational Health ; legislation & jurisprudence ; Occupational Health Services ; organization & administration ; standards

Endometrial Hyperplasia ; genetics ; pathology ; Female ; Genital Neoplasms, Female ; genetics ; pathology ; Humans ; Tandem Repeat Sequences ; Uterine Cervical Neoplasms ; etiology

The origin and development of "five elements motion and six kinds of qi" acupuncture technique are reviewed, and acupuncture for treatment and prevention of disorders of "five elements motion and six kinds of qi" is summarized. Also its principle is analyzed. Problems such as the inconformity of acupoint selection, lack of systematic theory are discussed. It is pointed out that, instead of indiscriminate copy, treatment should be based on the observation of the transportation and transformation of qi; it is suggested that the classics should be inherited and innovated, combining the tradition with contemporary, and according to a sixty-year cycle, the acupuncture technique of "five elements motion and six kinds of qi" can be improved systematically for promotion and application.
Acupuncture Points ; Acupuncture Therapy ; history ; methods ; Books ; history ; China ; History, Ancient ; Humans ; Medicine in Literature ; Meridians ; Qi ; history

ICU is the important place of ventilator associated pneumonia, the occurrence of fatality rate in patients with ventilator associated pneumonia is higher. In this paper, the cause of the ventilator associated pneumonia in ICU and nursing research progress are summarized, that enhance their awareness of the importance of nursing care and the use of normative evidence-based nursing in clinical practice thinking and nursing process, explore the nursing methods of more appropriate, to reduce the incidence of ventilator associated pneumonia in ICU is of great help.

BACKGROUND:Temperature measure methods of human tissue include destructive measurement and nondestructive measurement. Destructive measurement cannot measure three-dimensional (3D) temperature field and nondestructive measure is stil in the research stage. It is better way to build a mathematical and physical model to predict and simulate femur tumor hyperthermia. OBJECTIVE:To obtain the three-dimensional temperature distribution of femur and its surrounding tissues during tumor hyperthermia. METHODS:3D temperature distribution was obtained by using finite element method on the basis of heat conduction theory, Laplace equation, Pennes bio-heat transfer equation, thermo physical parameters of bone tissues, the boundary condition, and initial conditions. RESULTS AND CONCLUSION:The femur had good hinder effect to heat transfer. Femoral temperature curve in the 3D space showed el ipsoid distribution with heat source as the center;the closer from heat source, the greater the temperature gradient was. The three major diameters of temperature isoline were different at 50℃, which is maximum in cross section and minimum in the sagittal plane. In the three directions of the femur, transfer capability of temperature was different, so the radius of the inactivation of the tumor was also different. Because the 3D temperature space distribution of femur is asymmetry during hyperthermia, the necessary method is to use more than a heat source in order to avoid residual cancer tissue or destructive normal tissue.

BACKGROUND:Under normal physiological conditions, there is a homeostasis between the osteogenic and adipogenic differentiation of human bone marrow mesenchymal stem cel s. Osteogenic differentiation is an important process in the formation of skeleton in which differentiated and mature osteoblasts are indispensable. OBJECTIVE:To explore the role of miR-106a and its target gene, bone morphogenetic protein receptor 2 (BMPR2) in the differentiation of human bone marrow mesenchymal stem cel s into osteoblasts. METHODS:Human bone marrow mesenchymal stem cel s were induced to differentiate into osteoblasts by osteoblast-specific induction medium, and this process was detected by western blot and alkaline phosphatase staining. Overexpression of miR-106a was elicited by transfecting miR-106a mimics and the BMPR2 knockdown achieved by RNA interference. The expression levels of miR-106a and BMPR2 were detected by real-time PCR and western blot, respectively. The interaction of miR-106a and BMPR2 was verified by TargetScan software and dual luciferase report experiment assay. RESULTS AND CONCLUSION:The expression of miR-106a was decreased whereas the expression of BMPR2 increased with the progress of osteogenesis differentiation. When miR-106a was overexpressed, alkaline phosphatase activity was declined and the expressions of runt-related transcription factor 2 and osteocalcin, markers of osteogenesis differentiation, both decreased. The expression of BMPR2 was decreased as wel . BMPR2 was predicted to be the target gene of miR-106a by TargetScan software and this prediction proved by dual luciferase report experiments assay. Additional y, osteogenesis differentiation was inhibited by knocking down the expression of BMPR2. These results indicate that miR-106a regulates the differentiation of bone marrow mesenchymal stem cel s into osteoblasts by targeting BMPR2.

Statin therapy has become a standard method for the prevention of ischemic stroke,and is becoming a treatment option for acute ischemic stroke.The pleiotropic effects of statins which are independent of cholesterol are the main basis of using them in the treatment of ischemic stroke.It is regarded that these pleiotropic effects may have neuroprotective effects,thus improving the neurological functional outcome of patients.At the same time,studies have shown that the therapeutic effect of statins has dose-dependent manner; therefore,we advocate using high-dose statin therapy.However,about whether high-dose statins should be used in patients with ischemic stroke of the different mechanisms remain controversial.

ObjectiveObserving the distribution and the change of the quantity of SP,VIP in the colon tissue of 'cathartic colon'rats.MethodsWe divided the 32 wistar rats weighted (200 ±10)g into 2 groops randomly:the blank group( n =8) and model group( n =8).we induced the 'cathartic colon'rats with the suspension of dahuang.The blank group were given the distilled water for contrast.After one week during the time Dahuang was stopped.We killed them,measured the carbon powder propulsion rates in the intestine and then took Specimen after the 8 rats were fasted 24 hours as well as the blank group,but water were given.We compared the variation of SP,VIP distribution between two groups.ResultsThe carbon powder propulsion rates in the model group were slower than that in the saline control group.The distribution of SP,VIP are all more than that in the blank group.ConclusionThe distribution of SP,VIP are all more than that in the blank group.

ObjectiveTo study and compare the nursing effect of different nursing modes in patients with dysuria after transurethral electrovaporization of the prostate. Methods50 patients with dysuria after transurethral electrovaporization of the prostate from January 2007 to March 2011 were selected as research objects,and they were randomly divided into group A and group B with 25 cases in each group,group A was taken care with routine nursing method,group B adopted evidence-based nursing mode,then the rate of self- maturate,usage rate of catheter,time of indwelling catheter,maximum flow rate,relapse of dysuria,satisfaction degree,treatment compliance and quality of life before and after the nursing of two groups were analyzed and compared. ResultsThe rate of self-maturate and satisfaction degree of group B were higher than those of group A,usage rate of catheter and relapse of dysuria were lower than those of group A,time of indwelling catheter was shorter than that of group A,treatment compliance and quality of life were all better than those of group A,there were significant differences. ConclusionsThe nursing effect of evidence-based nursing mode in patients with dysuria after transurethral electrovaporization of the prostate is good,it can significantly improve the quality of life and is popular among patients.

There are many controversies for how to treat the occurrence of ischemic stroke on the basis of infective endocarditis would be more reasonable,especially there is no consensus on whether to treat with anticoagulants.The article discusses about this.