Cardiovascular Diseases ; drug therapy ; Humans ; Platelet Aggregation Inhibitors ; administration & dosage ; adverse effects ; therapeutic use

Asian Continental Ancestry Group ; Cardiovascular Diseases ; ethnology ; prevention & control ; Humans

Objective To compare the effects of two types of peripheral venous insertion of catheter in elderly patients with neurogliocytoma.Methods A total of 336 neurogliocytoma patients received intravenous drug treatment were randomly divided into two groups:midline catheter group (n =168) and periphery catheter group (n=168).The time course of venous insertion of catheter,frequency of insertion,time of catheter reservation,incidence of insertion complications and degree of satisfaction in patients were recorded.Results The time course of venous insertion and the time of catheter reservation were longer in midline group than in periphery group [(25.3±1.8) min vs.(0.8±0.1) min,(27.5±1.0) d vs.(2.9±0.4) d,respectively,both P＜0.05].The frequency of insertion and the incidence of phlebitis were lower in midline group than in periphery group [(1.1±0.3) vs.(12.2±0.4),8 cases (4.8％) vs.51 cases (30.4％),respectively,both P＜0.05].There were no significant differences in catheter occlusion,migration and removal between the two groups (all P＞ 0.05).The degree of satisfaction was higher in midline group than in periphery group (89.0％ vs.63.0％,P ＜ 0.05).Conclusions It is suitable for elderly patients with neurogliocytoma to recieve intravenous drug treatment by midline catheter insertion.Midline catheter insertion can reduce the incidence of phlebitis and puncture damage,and elevate the degree of satisfaction.

Hypoxia-inducible factor-1(HIF-1) is a key factor in hypoxic response of cells.It plays an important role in embryonic development,cerebral infarction,cerebral hemorrhage,hypoxic-ischemic encephalopathy,neurodegenerative diseases,cancers and other physiological or pathological processes.Studies have confirmed that in developing rats,the expression of HIF-1 α mRNA and HIF-1α in hippocampus after status epilepsy enhanced obviously,and it is related to proliferation of neural stem cells.Although some experiments have explored the relationship between certain signaling pathways and HIF-1 α,no experiments come to the signal-regulation in the expression of HIF-1α after epilepsy.

Twenty-one cases of hiccup caused by cerebral vascular accident were treated by synthetically applying auricular acupuncture, acupuncture or cupping therapy, after 3-10 treatment, all the patients were cured.

Objective To explore the value of Sysmex XE 5000 blood cell analyzer in alarm of atypical lymphocytes and basophil.Methods 198 samples of Sysmex XE 5000 blood cell analyzer and suggested that atypical lymphocytes and basophils, 915 copies of the instrument tip shaped specimens.Single lymphocyte increased blood smear microscopy for examination under a microscope to detect atypical lymphocytes as the gold standard and to verify the alarm not exactly.Results The microscopic examination results as the gold standard, and suggested that atypical lymphocytes and basophilia specimens after reinspection, eosinophilic granulocyte alkaline or positive value of 1.8%,in the normal range, the positive rate of atypical lymphocytes (129/198) was 65.2%,but the instrument alone atypical lymphocytes alarm specimens the positive rate of atypical lymphocytes after review of 72.4% microscope (663/915),the former was lower than the latter with significant difference (x2=4.521,P<0.05).Conclusion Sysmex XE 5000 blood cell analyzer at the same time of atypical lymphocyte and basophil alarm, two detection levels of interference, combined with microscope examination can improve detection accuracy, reduce the misdiagnosis rate, and provide reliable data for clinical treatment.

Objective To investigate the effect of auricular point sticking on insomnia in patients undergoing maintenance hemodialysis.Methods Sixty-four patients undergoing maintenance hemodialysis as well as suffering from insomnia were randomly divided into observation group and control group with equal number:The control group were treated by administering 1mg estazolam before going to bed and the observation group by auricular point sticking based on TCM theory.The two groups were compared in terms of score by Pittsburgh sleep quality index(PSQI)as well as the curative effects at weeks 4 and 8,respectively.Results The scores by PSQI in the observation group were significantly lower that those of the control group at the two time points(P<0.05,for both)and the sleep curative effect in the former was significantly better than the latter(P<0.05).Conclusion The auricular point sticking based on TCM theory is more effective than therapy right with western medicine in the treatment of insomnia in patients undergoing maintenance hemodialysis.

Objective:To improve the diagnostic level of lower extremity deep venous thrombosis ( LEDVT ) and decrease the rate of missed diagnosis.Methods:23 clinical cases which admitting diagnosed with LEDVT but final diagnoses weren't LEDVT were retrospectively analyzed in our hospital between 2000 and 2006.Results:Of these 23 cases with missed diagnosed,13 cases were gynecology tumor,1 case was adenomyosis,3 cases were rectal cancer,2 cases were lung cancer,2 cases were carcinoma of bladder,1 case was prostatic carcinoma,and 1 case was malignant lymphoma in ingina.Conclusion:clinicians should pay attention to question the case history when their patients get lower extremity deep venous thrombosis,especially to those whom are inconspicuous predisposing cause.

Objective:To summarize the experience of diagnosis and therapy of cerebral schistomiasis.Method:Clinial data,laboratory examination,CT and MRI results of 16 cases of cerebral schistomiasis were analyzed retrospectively.Results:All the cases were of chronic cerebral schistosomiasis,Conservation treatment was used in 10 cases after aetiological diagnosis and surgical treatment was used in 6 cases misdiagnosed as cerebral tumor.All cases had good recovery.Conclusions:The diagnosis of cerebral schitosomiasis should be made basing on the history,onste symptom,imaging data,examination of aetiology and so on in order to improve the accuracy rate.Pyquiton has the positive effect in treating cerebral schistomiasis.

Objective:We summarized the therapeutic results of 68 differently located urinary fistulae after kidney transplantation in order to approach optimal treatments for them. Methods: Between December 1994 and July 2008, fistulae were observed in 68 of 1263 patients (5.4%) after kidney transplantation,including 26 lower fistulae and 42 upper fistulae. The former included vesical fistulae and stoma fistulae,while the latter included ureter fistulae,pelvis fistulae.The location of fistulae was determined by cystography, magnetic resonance hydrography(MRH) or operation research. In both groups we first adopted conservative treatment which was placing a negative pressure drainage tube draining the wounds and placing a double-J catheter or a urinary canal in,however,if invalid,we resorted to surgical repair. Subsequently, therapeutic efficacies of differently located fistulae observed. Results: Twenty of 26 lower fistulae(76.9%) were cured successfully by conservative treatment For the remaining 6 cases(23.1%),we had to turn to open surgery, among which 5 were cured and 1 underwent nephrectomy because of acute rejection. Only 8 of 42 upper fistula(19.0%)were cured by conservative treatment, but the other 34(81.0%)cases accepted open surgery among which 29 were cured, and 3 underwent nephrectomy owing to acute rejection (1 case)and failure of surgery(2 cases), and 2 died of pulmonary infection. The achievement ratio of conservative treatment in lower fistulae was significantly higher than that of upper fistulae(76.9% vs. 19.0%,P