4.Progress on proteome of rheumatoid arthritis
International Journal of Pediatrics 2010;37(3):240-242
Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting joints. Proteomics is a new field of studying the protein and its dynamic axiom of transmutation in cells. Two-dimensional gel electrophoresis, mass spectrometry and bioinformatics are the three major technology. Recently,the research in rheumatoid arthritis proteomics has made great progress. Application of proteomics technology is designed to study the pathogenesis from the proteins levels,finding out the marker proteins in order to improue RA diagnosis, treatment and prognosis.
5.Combined use of duodenoscopy and laparoscopy for treatment of calculus of extrahepatic bile duct
Chinese Journal of General Surgery 2000;0(12):-
Objective To discuss the clinical effect of combined use of duodenoscopy and laparoscopy for treatment of cholecystolithiasis complicated by choledocholithiasis.Methods The clinical data of 106 cases of cholecystolithiasis with cholelcoholithiasis in our department during 7 years were analyzed.Endoscopic sphincteromy (EST) and endoscopic nasobiliary drainage (ENBD), followed by laparoscopic cholecystectomy(LC) was employed. Results In 101 cases(95.3 %) stones were removed by EST successfully. Complicated with postoperative pancreatitis in 11cases(10.4 %), bleeding in 1 case (0.9 %), and acute cholangitis in 2 cases (1.9 %). All of the patients recovered and discharged. Eighty-five cases were followed up for average 3.1 years. Of them, 5 cases had choledocholithiasis recurrence, 1 had papillary re-stenosis, 2 had bile duct carcinoma, and 2 died of other caused.Conclusions Combined use of EST and LC for treatment of calculus of extrahepatic bile duct is a safe and effective mini-intrusive operation.
6.Strategy of differently located urinary fistulae after kidney transplantation
Journal of Chongqing Medical University 2007;0(09):-
Objective:We summarized the therapeutic results of 68 differently located urinary fistulae after kidney transplantation in order to approach optimal treatments for them. Methods: Between December 1994 and July 2008, fistulae were observed in 68 of 1263 patients (5.4%) after kidney transplantation,including 26 lower fistulae and 42 upper fistulae. The former included vesical fistulae and stoma fistulae,while the latter included ureter fistulae,pelvis fistulae.The location of fistulae was determined by cystography, magnetic resonance hydrography(MRH) or operation research. In both groups we first adopted conservative treatment which was placing a negative pressure drainage tube draining the wounds and placing a double-J catheter or a urinary canal in,however,if invalid,we resorted to surgical repair. Subsequently, therapeutic efficacies of differently located fistulae observed. Results: Twenty of 26 lower fistulae(76.9%) were cured successfully by conservative treatment For the remaining 6 cases(23.1%),we had to turn to open surgery, among which 5 were cured and 1 underwent nephrectomy because of acute rejection. Only 8 of 42 upper fistula(19.0%)were cured by conservative treatment, but the other 34(81.0%)cases accepted open surgery among which 29 were cured, and 3 underwent nephrectomy owing to acute rejection (1 case)and failure of surgery(2 cases), and 2 died of pulmonary infection. The achievement ratio of conservative treatment in lower fistulae was significantly higher than that of upper fistulae(76.9% vs. 19.0%,P
7.Hypopharynx and cervical esophagus reconstruction with remaining larynx and pharynx after operation on the advanced pyriform sinus cancer
Journal of Chongqing Medical University 2003;0(06):-
Objective:To evaluate the outcome of hypopharynx reconstruction using remaining larynx and pharynx in patients after hemipharyngectomy,partial laryngectomy and cervical esophagectomy.Methods:Twelve patients with advanced pyriform sinus cancer underwent hemipharyngectomy and partial laryngectomy.Two patients underwent cervical esophagectomy at the same time.All cases were reconstructed by the remaining larynx.Results:All cases were successful.Only one patient suffered from postoperative pharyngocutaneous fistulas,who had had perioperative radiotherapy.Patients could swallow ordinary foods and had no strictures after operation.Up to now,patients have been followed over 2 years,and two-year survival rate was 75%.One case has survived over 5 years. Conclusion:The hypopharynx reconstruction with remaining larynx and pharynx is simple and convenient.It is less invasive and has less complication.
8.Several suggestions on upgrading management for accelerating Chinese materia medica internationalization
Chinese Traditional and Herbal Drugs 1994;0(02):-
With a global attempt of regressing into the natural field, natural medicine has the best future after the chemical and biological medicine, all countries pay more attention to it.Japan and Germany represent the higher level of modernization of plant medicine with taking the lead of natural medicine.Traditional Chinese medicine possesses the advantages, such as several thousand year culture and a great deal of clinic experiences.Moreover, our herbal enterprises are also on the way to the world.While the inter- nationalization is facing multiform barriers and various problems in our running.The management and actuality of herbal medicine in Japan and Germany and the existing problems of Chinese materia medica management have been reviewed in this paper, so as to put forward some advices for the management reform adapting to the internationalization of Chinese materia medica industry.
9.Analysis of the Sysmex XE 5000 blood cell analyzer for the analysis of abnormal lymphocytes and basophils
Chinese Journal of Primary Medicine and Pharmacy 2017;24(10):1560-1562
Objective To explore the value of Sysmex XE 5000 blood cell analyzer in alarm of atypical lymphocytes and basophil.Methods 198 samples of Sysmex XE 5000 blood cell analyzer and suggested that atypical lymphocytes and basophils, 915 copies of the instrument tip shaped specimens.Single lymphocyte increased blood smear microscopy for examination under a microscope to detect atypical lymphocytes as the gold standard and to verify the alarm not exactly.Results The microscopic examination results as the gold standard, and suggested that atypical lymphocytes and basophilia specimens after reinspection, eosinophilic granulocyte alkaline or positive value of 1.8%,in the normal range, the positive rate of atypical lymphocytes (129/198) was 65.2%,but the instrument alone atypical lymphocytes alarm specimens the positive rate of atypical lymphocytes after review of 72.4% microscope (663/915),the former was lower than the latter with significant difference (x2=4.521,P<0.05).Conclusion Sysmex XE 5000 blood cell analyzer at the same time of atypical lymphocyte and basophil alarm, two detection levels of interference, combined with microscope examination can improve detection accuracy, reduce the misdiagnosis rate, and provide reliable data for clinical treatment.
10.The Influences of Anxiety on Foreign Language Study
Chinese Journal of Medical Education Research 2006;0(10):-
The author thinks the causes of foreign language anxiety includes the imbalance between input and output,the neglect of individual differences because of the teacher-centered input model and the passive affects of dull classroom environment etc. Meanwhile,from the author's point of view,teachers should realize the passive affects of foreign language anxiety,and try to overcome it in the teaching process.